SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 ALA A 196
VAL A 198
TRP A 169
 None
 0.80A 1av2C-3s51A:
undetectable
1av2D-3s51A:
undetectable		 1av2C-3s51A:
1.35
1av2D-3s51A:
1.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 8 PHE A 385
SER A 361
ILE A 364
LEU A 365
 None
 0.76A 1eupA-3s51A:
1.0		 1eupA-3s51A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 GLN A 325
ILE A 272
HIS A 377
 None
 0.68A 1fm9A-3s51A:
undetectable		 1fm9A-3s51A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 6 LYS A 197
LEU A 193
ALA A 196
SER A 225
 None
 0.88A 1ictB-3s51A:
undetectable		 1ictB-3s51A:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 GLN A 325
ILE A 272
HIS A 377
 None
 0.68A 1k74A-3s51A:
undetectable		 1k74A-3s51A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 11 GLU A 909
PHE A 915
GLY A 910
ARG A 990
LEU A 919
 None
 1.28A 1mjqA-3s51A:
undetectable
1mjqB-3s51A:
undetectable		 1mjqA-3s51A:
6.57
1mjqB-3s51A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 ALA A 196
VAL A 198
TRP A 169
 None
 0.85A 1nt6A-3s51A:
undetectable		 1nt6A-3s51A:
1.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 ALA A 196
VAL A 198
TRP A 169
 None
 0.85A 1nt6B-3s51A:
undetectable		 1nt6B-3s51A:
1.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 7 PHE A 958
GLU A 977
TYR A 884
LEU A 908
 None
 1.19A 1rmtB-3s51A:
undetectable		 1rmtB-3s51A:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 LEU A 908
LEU A 905
SER A 902
 None
 0.62A 1tlmA-3s51A:
undetectable		 1tlmA-3s51A:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 12 LEU A 108
LEU A 105
ILE A  68
ILE A 132
LEU A 129
 None
 0.87A 1tw4A-3s51A:
undetectable		 1tw4A-3s51A:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 12 LEU A 108
LEU A 105
ILE A  68
ILE A 132
LEU A 129
 None
 0.93A 1tw4B-3s51A:
undetectable		 1tw4B-3s51A:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 ASP A  28
ARG A  64
ASP A  26
 None
 0.92A 1vptA-3s51A:
undetectable		 1vptA-3s51A:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 ALA A 196
VAL A 198
TRP A 169
 None
 0.79A 1w5uC-3s51A:
undetectable
1w5uD-3s51A:
undetectable		 1w5uC-3s51A:
1.35
1w5uD-3s51A:
1.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 TRP A 169
ALA A 196
VAL A 198
 None
 0.69A 2izqA-3s51A:
undetectable
2izqB-3s51A:
undetectable		 2izqA-3s51A:
1.35
2izqB-3s51A:
1.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 12 LEU A 330
GLY A 381
ILE A 319
ILE A 272
VAL A 326
 None
 0.93A 2nnkB-3s51A:
undetectable		 2nnkB-3s51A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 12 LEU A 933
PHE A 929
ILE A 876
SER A 961
LEU A 981
 None
 1.23A 2po7B-3s51A:
undetectable		 2po7B-3s51A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 7 ILE A 849
ILE A 903
LEU A 873
LEU A 812
 None
 0.74A 3adxA-3s51A:
undetectable		 3adxA-3s51A:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 6 THR A1006
ILE A 982
SER A1023
LEU A1024
 None
 0.96A 3deuB-3s51A:
undetectable		 3deuB-3s51A:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 12 ALA A  42
ASP A   2
LEU A   3
LYS A   4
SER A   7
 None
 0.88A 3hj3B-3s51A:
undetectable		 3hj3B-3s51A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 ALA A 196
VAL A 198
TRP A 169
 None
 0.69A 3l8lA-3s51A:
undetectable
3l8lB-3s51A:
undetectable		 3l8lA-3s51A:
1.35
3l8lB-3s51A:
1.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 ALA A 196
VAL A 198
TRP A 169
 None
 0.81A 3l8lC-3s51A:
undetectable
3l8lD-3s51A:
undetectable		 3l8lC-3s51A:
1.35
3l8lD-3s51A:
1.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 7 LEU A 353
LEU A 350
SER A 347
VAL A1039
 None
 0.96A 3ozkB-3s51A:
undetectable		 3ozkB-3s51A:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 TYR A 173
LEU A 199
LYS A 197
 None
 0.79A 3sueD-3s51A:
undetectable		 3sueD-3s51A:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 12 PHE A 525
GLY A 595
LEU A 594
GLN A 596
PHE A 608
 None
 1.34A 3tbgA-3s51A:
2.2		 3tbgA-3s51A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 7 LEU A  32
GLY A  40
GLU A  88
ALA A  42
 None
 1.01A 3tehB-3s51A:
undetectable		 3tehB-3s51A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 12 ILE A 210
GLU A 247
TYR A 265
HIS A 266
VAL A 271
 None
 1.15A 4a97B-3s51A:
5.3
4a97C-3s51A:
4.9		 4a97B-3s51A:
12.18
4a97C-3s51A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 7 GLU A 247
TYR A 265
HIS A 266
VAL A 271
 None
 1.10A 4a97D-3s51A:
4.9		 4a97D-3s51A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 5 GLU A 750
PHE A 808
TYR A 840
HIS A 839
 None
 1.46A 4a97J-3s51A:
3.0		 4a97J-3s51A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 4 LEU A 121
ILE A  73
GLY A 124
PHE A 112
 None
 0.84A 4dc3A-3s51A:
undetectable		 4dc3A-3s51A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 8 ASP A 328
VAL A 360
PHE A 385
LEU A 389
 None
 1.07A 4f8hA-3s51A:
undetectable
4f8hB-3s51A:
undetectable		 4f8hA-3s51A:
13.42
4f8hB-3s51A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 8 ASP A 328
VAL A 360
PHE A 385
LEU A 389
 None
 1.09A 4f8hC-3s51A:
undetectable
4f8hD-3s51A:
undetectable		 4f8hC-3s51A:
13.42
4f8hD-3s51A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 8 ASP A 328
VAL A 360
PHE A 385
LEU A 389
 None
 1.08A 4f8hD-3s51A:
undetectable
4f8hE-3s51A:
undetectable		 4f8hD-3s51A:
13.42
4f8hE-3s51A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 6 ILE A1135
TYR A1181
TYR A1180
PHE A1177
 None
 1.13A 4g10A-3s51A:
4.3		 4g10A-3s51A:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 12 LEU A  32
ALA A  49
ILE A  89
GLY A  44
GLY A  40
 None
 1.27A 4hfpB-3s51A:
undetectable		 4hfpB-3s51A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 7 LYS A 197
LEU A 193
THR A 200
ALA A 196
 None
 0.96A 4ik7A-3s51A:
undetectable		 4ik7A-3s51A:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 LYS A 197
LEU A 193
ALA A 196
 None
 0.59A 4ikiA-3s51A:
undetectable		 4ikiA-3s51A:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MF6_A_BEZA303_0
(GLUTATHIONE
S-TRANSFERASE DOMAIN)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 5 THR A1194
PRO A1192
PHE A1177
TYR A1181
 None
 1.38A 4mf6A-3s51A:
2.9		 4mf6A-3s51A:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 ASP A 241
LEU A 240
PHE A 237
 None
 0.70A 4pthA-3s51A:
undetectable		 4pthA-3s51A:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 6 LEU A 344
LEU A 353
VAL A 354
PHE A 349
 None
 1.22A 4uswA-3s51A:
undetectable		 4uswA-3s51A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 7 VAL A 334
ILE A 425
ARG A 318
ILE A 383
 None
 0.77A 4uxqA-3s51A:
undetectable		 4uxqA-3s51A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_A_ACTA202_0
(NITROGEN REGULATORY
PROTEIN P-II)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 4 VAL A  43
GLY A  44
ARG A  41
VAL A  85
 None
 1.36A 5d4nA-3s51A:
undetectable
5d4nB-3s51A:
undetectable		 5d4nA-3s51A:
6.00
5d4nB-3s51A:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 ASP A 610
ASN A 615
PHE A 546
 None
 0.54A 5dsgB-3s51A:
undetectable		 5dsgB-3s51A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 8 MET A 623
LEU A 626
LEU A 667
LEU A 674
 None
 0.84A 5dxeA-3s51A:
undetectable		 5dxeA-3s51A:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 12 LEU A 930
TYR A 884
ILE A 903
LEU A 980
PHE A 958
 None
 1.21A 5eshA-3s51A:
undetectable		 5eshA-3s51A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 6 CYH A1081
LEU A1154
HIS A1050
LEU A1149
 None
 1.01A 5hpuC-3s51A:
undetectable
5hpuD-3s51A:
undetectable		 5hpuC-3s51A:
3.24
5hpuD-3s51A:
3.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 12 LEU A 460
PHE A 463
LEU A 506
THR A 483
LEU A 520
 None
 1.29A 5ienA-3s51A:
undetectable		 5ienA-3s51A:
7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 8 ILE A 456
MET A 390
ILE A 466
LEU A 490
 None
 0.96A 5ieoA-3s51A:
undetectable		 5ieoA-3s51A:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 7 LEU A 630
TYR A 634
ASP A 639
LEU A 667
 None
 0.80A 5jq7B-3s51A:
0.6		 5jq7B-3s51A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 ASP A 610
ASN A 545
GLN A 503
 None
 0.80A 5k7uA-3s51A:
undetectable		 5k7uA-3s51A:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 THR A 452
SER A 454
ASP A 391
 None
 0.82A 5kvaA-3s51A:
undetectable		 5kvaA-3s51A:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 THR A 452
SER A 454
ASP A 391
 None
 0.81A 5kvaB-3s51A:
undetectable		 5kvaB-3s51A:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_2
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 5 LEU A 498
VAL A 502
MET A 512
CYH A 477
 None
 1.34A 5te0A-3s51A:
undetectable		 5te0A-3s51A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 6 ILE A1191
LEU A1274
HIS A1277
PHE A1177
 None
 1.08A 5vkqA-3s51A:
3.2
5vkqB-3s51A:
3.2		 5vkqA-3s51A:
21.75
5vkqB-3s51A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 6 PHE A1177
ILE A1191
LEU A1274
HIS A1277
 None
 1.07A 5vkqA-3s51A:
3.2
5vkqD-3s51A:
3.2		 5vkqA-3s51A:
21.75
5vkqD-3s51A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 12 LEU A 313
VAL A 326
SER A 333
PHE A 385
VAL A 367
 None
 1.45A 6a94A-3s51A:
2.2		 6a94A-3s51A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		3 / 3 HIS A  98
HIS A  99
ARG A  65
 None
 0.69A 6b58A-3s51A:
6.2		 6b58A-3s51A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		4 / 8 MET A 623
LEU A 626
LEU A 667
LEU A 674
 None
 0.84A 6cbzA-3s51A:
undetectable		 6cbzA-3s51A:
5.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 10 LEU A 218
SER A 221
ILE A 233
SER A 228
GLY A 232
 None
 1.09A 6dlzA-3s51A:
undetectable
6dlzD-3s51A:
3.0		 6dlzA-3s51A:
6.07
6dlzD-3s51A:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 10 ILE A 233
SER A 228
GLY A 232
LEU A 218
SER A 221
 None
 1.09A 6dlzB-3s51A:
2.9
6dlzC-3s51A:
undetectable		 6dlzB-3s51A:
6.07
6dlzC-3s51A:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 10 LEU A 218
SER A 221
ILE A 233
SER A 228
GLY A 232
 None
 1.09A 6dm1A-3s51A:
undetectable
6dm1D-3s51A:
3.0		 6dm1A-3s51A:
6.07
6dm1D-3s51A:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 10 ILE A 233
SER A 228
GLY A 232
LEU A 218
SER A 221
 None
 1.10A 6dm1B-3s51A:
2.9
6dm1C-3s51A:
undetectable		 6dm1B-3s51A:
6.07
6dm1C-3s51A:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG
(Mus
musculus) 		5 / 11 VAL A 219
LEU A 218
ALA A 235
PHE A 202
VAL A 198
 None
 1.20A 6dryA-3s51A:
undetectable		 6dryA-3s51A:
15.89