SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s5c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3s5c LINA
(uncultured
organism) 		4 / 5 TYR B  68
LEU B  64
VAL B  24
VAL B  94
 None
 1.20A 2m56A-3s5cB:
undetectable		 2m56A-3s5cB:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 3s5c LINA
(uncultured
organism) 		5 / 12 GLY B 131
ASN B 130
ILE B 109
HIS B  73
THR B  71
 None
 1.11A 3eeyC-3s5cB:
undetectable		 3eeyC-3s5cB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 3s5c LINA
(uncultured
organism) 		5 / 12 GLY B 131
ASN B 130
ILE B 109
HIS B  73
THR B  71
 None
 1.12A 3eeyE-3s5cB:
undetectable		 3eeyE-3s5cB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 3s5c LINA
(uncultured
organism) 		3 / 3 GLU B  45
GLY B  48
THR B  49
 None
 0.50A 3iazA-3s5cB:
undetectable		 3iazA-3s5cB:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3s5c LINA
(uncultured
organism) 		4 / 6 ILE B  72
VAL B  24
LEU B  32
ILE B  22
 None
 0.88A 4asdA-3s5cB:
undetectable		 4asdA-3s5cB:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 3s5c LINA
(uncultured
organism) 		5 / 12 LEU B  64
LEU B 100
ILE B 109
ILE B  47
ILE B  44
 None
 0.99A 4odrA-3s5cB:
undetectable
4odrB-3s5cB:
undetectable		 4odrA-3s5cB:
18.99
4odrB-3s5cB:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 3s5c LINA
(uncultured
organism) 		4 / 7 GLY B  98
GLN B  20
TYR B 113
ASP B  25
 None
 1.00A 5vlmE-3s5cB:
undetectable		 5vlmE-3s5cB:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 3s5c LINA
(uncultured
organism) 		4 / 7 GLY B  98
GLN B  20
TYR B 113
ASP B  25
 None
 1.13A 5vlmG-3s5cB:
undetectable		 5vlmG-3s5cB:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 3s5c LINA
(uncultured
organism) 		4 / 7 GLY B  55
ALA B  56
VAL B  24
LEU B  64
 None
 0.85A 6dwnB-3s5cB:
undetectable		 6dwnB-3s5cB:
17.61