SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s5p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 3s5p RIBOSE 5-PHOSPHATE
ISOMERASE
(Giardia
intestinalis) 		5 / 12 ALA A 105
GLY A 107
ILE A  62
ALA A 103
ILE A  69
 None
 1.10A 1ve3B-3s5pA:
undetectable		 1ve3B-3s5pA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 3s5p RIBOSE 5-PHOSPHATE
ISOMERASE
(Giardia
intestinalis) 		4 / 6 LEU A  14
MET A  16
GLY A  10
LEU A  18
 None
 0.95A 3aiaA-3s5pA:
3.2		 3aiaA-3s5pA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3s5p RIBOSE 5-PHOSPHATE
ISOMERASE
(Giardia
intestinalis) 		5 / 12 PHE A 123
LEU A  85
ALA A  84
ALA A 101
VAL A  53
 None
 1.22A 3cwkA-3s5pA:
undetectable		 3cwkA-3s5pA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_B_SALB201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3s5p RIBOSE 5-PHOSPHATE
ISOMERASE
(Giardia
intestinalis) 		5 / 9 ARG A  96
ALA A  22
VAL A   3
MET A   1
ILE A  62
 None
 1.37A 3retB-3s5pA:
undetectable		 3retB-3s5pA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 3s5p RIBOSE 5-PHOSPHATE
ISOMERASE
(Giardia
intestinalis) 		4 / 5 PHE A  45
ILE A  71
GLY A  70
THR A  67
 None
SO4  A 146 (-4.0A)
SO4  A 146 (-3.3A)
SO4  A 146 (-3.9A)
 1.01A 4ejjC-3s5pA:
undetectable		 4ejjC-3s5pA:
16.63