SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s5q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DV4_A_NMYA601_2 (CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE)	3s5q	PUTATIVE GLYCOSYLHYDROLASE (Parabacteroides distasonis)	3 / 3	GLU A 103 TRP A 121 ASN A 84	None	1.02A	5dv4A-3s5qA: undetectable	5dv4A-3s5qA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGT_A_ERYA402_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	3s5q	PUTATIVE GLYCOSYLHYDROLASE (Parabacteroides distasonis)	5 / 12	HIS A 129 ALA A 168 VAL A 166 GLY A 153 THR A 198	None None EDO A 303 ( 4.4A) EDO A 308 ( 4.3A) EDO A 308 (-3.0A)	1.02A	5igtA-3s5qA: undetectable	5igtA-3s5qA: 19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_C_CVIC301_1 (REGULATORY PROTEIN TETR)	3s5q	PUTATIVE GLYCOSYLHYDROLASE (Parabacteroides distasonis)	4 / 7	GLN A 60 ILE A 98 TRP A 63 TYR A 127	None	1.09A	5vlmC-3s5qA: undetectable	5vlmC-3s5qA: 22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_F_CVIF301_1 (REGULATORY PROTEIN TETR)	3s5q	PUTATIVE GLYCOSYLHYDROLASE (Parabacteroides distasonis)	4 / 8	TRP A 121 ARG A 122 GLN A 105 TYR A 127	None	1.14A	5vlmF-3s5qA: undetectable	5vlmF-3s5qA: 22.55

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5DV4_A_NMYA601_2","CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE","3s5q","PUTATIVE GLYCOSYLHYDROLASE","Parabacteroides distasonis",3,"GLU A 103;TRP A 121;ASN A  84","None","1.02A","5dv4A-3s5qA:undetectable","5dv4A-3s5qA:20.16"],["5IGT_A_ERYA402_0","MACROLIDE 2'-PHOSPHOTRANSFERASE","3s5q","PUTATIVE GLYCOSYLHYDROLASE","Parabacteroides distasonis",5,"HIS A 129;ALA A 168;VAL A 166;GLY A 153;THR A 198","None;None;EDO A 303 ( 4.4A);EDO A 308 ( 4.3A);EDO A 308 (-3.0A)","1.02A","5igtA-3s5qA:undetectable","5igtA-3s5qA:19.74"],["5VLM_C_CVIC301_1","REGULATORY PROTEIN TETR","3s5q","PUTATIVE GLYCOSYLHYDROLASE","Parabacteroides distasonis",4,"GLN A  60;ILE A  98;TRP A  63;TYR A 127","None","1.09A","5vlmC-3s5qA:undetectable","5vlmC-3s5qA:22.55"],["5VLM_F_CVIF301_1","REGULATORY PROTEIN TETR","3s5q","PUTATIVE GLYCOSYLHYDROLASE","Parabacteroides distasonis",4,"TRP A 121;ARG A 122;GLN A 105;TYR A 127","None","1.14A","5vlmF-3s5qA:undetectable","5vlmF-3s5qA:22.55"]]