SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s5u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDR_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.01A 1ddrB-3s5uA:
undetectable		 1ddrB-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.96A 1drbB-3s5uA:
undetectable		 1drbB-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.09A 1drfA-3s5uA:
undetectable		 1drfA-3s5uA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.04A 1dyiA-3s5uA:
undetectable		 1dyiA-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.06A 1dyiB-3s5uA:
undetectable		 1dyiB-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.00A 1jolA-3s5uA:
undetectable		 1jolA-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.00A 1jolB-3s5uA:
undetectable		 1jolB-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.01A 1ra2A-3s5uA:
undetectable		 1ra2A-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.01A 1rb2A-3s5uA:
undetectable		 1rb2A-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.00A 1rd7A-3s5uA:
undetectable		 1rd7A-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.03A 1re7B-3s5uA:
undetectable		 1re7B-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.00A 1rx2A-3s5uA:
undetectable		 1rx2A-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.93A 1rx3A-3s5uA:
undetectable		 1rx3A-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.97A 1rx8A-3s5uA:
undetectable		 1rx8A-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.02A 1tdrA-3s5uA:
undetectable		 1tdrA-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 6 ILE A  35
ILE A  65
TYR A 172
LEU A  31
 None
 1.16A 3adsA-3s5uA:
undetectable		 3adsA-3s5uA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_1
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.08A 3ia4D-3s5uA:
undetectable		 3ia4D-3s5uA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.98A 3ql0A-3s5uA:
undetectable		 3ql0A-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 LEU A 119
HIS A 115
MET A 117
 None
 0.93A 3thrD-3s5uA:
undetectable		 3thrD-3s5uA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 SER A 159
ASP A  82
ASP A  89
 None
 0.73A 3uj7A-3s5uA:
undetectable		 3uj7A-3s5uA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.99A 4ej1A-3s5uA:
undetectable		 4ej1A-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.10A 4ej1B-3s5uA:
undetectable		 4ej1B-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.00A 4fhbA-3s5uA:
undetectable		 4fhbA-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.00A 4kjjA-3s5uA:
undetectable		 4kjjA-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.99A 4kjkA-3s5uA:
undetectable		 4kjkA-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.98A 4kjlA-3s5uA:
undetectable		 4kjlA-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 SER A 159
ASP A  82
ASP A  89
 None
 0.73A 4mwzA-3s5uA:
undetectable		 4mwzA-3s5uA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 9 ILE A  65
ILE A 167
THR A 152
ILE A 185
VAL A 181
 None
 1.05A 4nptA-3s5uA:
undetectable		 4nptA-3s5uA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.94A 4p3qA-3s5uA:
undetectable		 4p3qA-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.98A 4p3rA-3s5uA:
undetectable		 4p3rA-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.95A 4pssA-3s5uA:
undetectable		 4pssA-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.97A 4psyA-3s5uA:
undetectable		 4psyA-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.02A 4qleA-3s5uA:
undetectable		 4qleA-3s5uA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 11 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.00A 4qlfA-3s5uA:
undetectable		 4qlfA-3s5uA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.03A 4qlgA-3s5uA:
undetectable		 4qlgA-3s5uA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.99A 4qlgB-3s5uA:
undetectable		 4qlgB-3s5uA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RGC_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.95A 4rgcA-3s5uA:
undetectable		 4rgcA-3s5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.00A 4x5fA-3s5uA:
undetectable		 4x5fA-3s5uA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.00A 4x5fB-3s5uA:
undetectable		 4x5fB-3s5uA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.02A 4x5gA-3s5uA:
undetectable		 4x5gA-3s5uA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5H_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.04A 4x5hA-3s5uA:
undetectable		 4x5hA-3s5uA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.01A 5e8qB-3s5uA:
undetectable		 5e8qB-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.01A 5eajB-3s5uA:
undetectable		 5eajB-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 LEU A 158
TYR A  68
SER A  72
 None
 0.80A 5iktA-3s5uA:
undetectable		 5iktA-3s5uA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.00A 5ujxB-3s5uA:
undetectable		 5ujxB-3s5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.99A 5z6jA-3s5uA:
undetectable		 5z6jA-3s5uA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 0.99A 5z6kA-3s5uA:
undetectable		 5z6kA-3s5uA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3s5u PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 135
ALA A 132
PHE A 130
ILE A  97
LEU A  87
 None
 1.06A 7dfrA-3s5uA:
undetectable		 7dfrA-3s5uA:
22.27