SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s6c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 3s6c BETA-2-MICROGLOBULIN
, T-CELL SURFACE
GLYCOPROTEIN CD1E,
MEMBRANE-ASSOCIATED
(Homo
sapiens) 		4 / 7 TRP A  49
GLY A  52
PHE A  45
HIS A  34
 None
 1.09A 2ackA-3s6cA:
undetectable		 2ackA-3s6cA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3s6c BETA-2-MICROGLOBULIN
, T-CELL SURFACE
GLYCOPROTEIN CD1E,
MEMBRANE-ASSOCIATED
(Homo
sapiens) 		3 / 3 PHE A  70
SER A  12
GLN A  10
 None
 0.93A 3smtA-3s6cA:
undetectable		 3smtA-3s6cA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3s6c BETA-2-MICROGLOBULIN
, T-CELL SURFACE
GLYCOPROTEIN CD1E,
MEMBRANE-ASSOCIATED
(Homo
sapiens) 		3 / 3 PHE A  70
SER A  22
GLN A  10
 None
 0.82A 3smtA-3s6cA:
undetectable		 3smtA-3s6cA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3s6c BETA-2-MICROGLOBULIN
, T-CELL SURFACE
GLYCOPROTEIN CD1E,
MEMBRANE-ASSOCIATED
(Homo
sapiens) 		3 / 3 ARG A  44
TRP A  36
GLY A  41
 None
 0.86A 4e7cA-3s6cA:
undetectable		 4e7cA-3s6cA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3s6c BETA-2-MICROGLOBULIN
, T-CELL SURFACE
GLYCOPROTEIN CD1E,
MEMBRANE-ASSOCIATED
(Homo
sapiens) 		5 / 12 LEU A 154
HIS A  34
MET A   8
LEU A  28
GLY A 165
 None
 1.12A 5d4uA-3s6cA:
undetectable		 5d4uA-3s6cA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 3s6c BETA-2-MICROGLOBULIN
, T-CELL SURFACE
GLYCOPROTEIN CD1E,
MEMBRANE-ASSOCIATED
(Homo
sapiens) 		4 / 4 VAL A 198
GLY A 187
ASP A1098
ASP A1100
 None
 0.86A 6cjkC-3s6cA:
10.7		 6cjkC-3s6cA:
16.58