SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s6f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		4 / 4 GLY A  88
SER A  91
VAL A  80
LEU A   6
 GLY  A  88 (-0.0A)
SER  A  91 (-0.0A)
VAL  A  80 (-0.6A)
LEU  A   6 ( 0.5A)
 1.29A 1yajB-3s6fA:
undetectable		 1yajB-3s6fA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		3 / 3 TRP A  40
ALA A  21
VAL A  18
 TRP  A  40 ( 0.5A)
ALA  A  21 ( 0.0A)
VAL  A  18 ( 0.5A)
 0.94A 2izqC-3s6fA:
undetectable
2izqD-3s6fA:
undetectable		 2izqC-3s6fA:
7.87
2izqD-3s6fA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		3 / 3 TRP A  40
ALA A  21
VAL A  18
 TRP  A  40 ( 0.5A)
ALA  A  21 ( 0.0A)
VAL  A  18 ( 0.5A)
 0.99A 3l8lA-3s6fA:
undetectable
3l8lB-3s6fA:
undetectable		 3l8lA-3s6fA:
7.87
3l8lB-3s6fA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		3 / 3 TRP A  40
ALA A  21
VAL A  18
 TRP  A  40 ( 0.5A)
ALA  A  21 ( 0.0A)
VAL  A  18 ( 0.5A)
 0.93A 3l8lC-3s6fA:
undetectable
3l8lD-3s6fA:
undetectable		 3l8lC-3s6fA:
7.87
3l8lD-3s6fA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		5 / 11 LEU A  39
LEU A  23
LEU A  43
ALA A  52
LEU A  51
 LEU  A  39 ( 0.5A)
LEU  A  23 ( 0.6A)
LEU  A  43 ( 0.6A)
ALA  A  52 ( 0.0A)
LEU  A  51 ( 0.5A)
 1.09A 4wg0B-3s6fA:
undetectable
4wg0C-3s6fA:
undetectable
4wg0D-3s6fA:
undetectable		 4wg0B-3s6fA:
8.62
4wg0C-3s6fA:
8.62
4wg0D-3s6fA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		5 / 11 LEU A  39
LEU A  23
LEU A  43
ALA A  52
LEU A  51
 LEU  A  39 ( 0.5A)
LEU  A  23 ( 0.6A)
LEU  A  43 ( 0.6A)
ALA  A  52 ( 0.0A)
LEU  A  51 ( 0.5A)
 1.11A 4wg0D-3s6fA:
undetectable
4wg0E-3s6fA:
undetectable
4wg0F-3s6fA:
undetectable		 4wg0D-3s6fA:
8.62
4wg0E-3s6fA:
8.62
4wg0F-3s6fA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		5 / 11 LEU A  39
LEU A  23
LEU A  43
ALA A  52
LEU A  51
 LEU  A  39 ( 0.5A)
LEU  A  23 ( 0.6A)
LEU  A  43 ( 0.6A)
ALA  A  52 ( 0.0A)
LEU  A  51 ( 0.5A)
 1.11A 4wg0F-3s6fA:
undetectable
4wg0G-3s6fA:
undetectable
4wg0H-3s6fA:
undetectable		 4wg0F-3s6fA:
8.62
4wg0G-3s6fA:
8.62
4wg0H-3s6fA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		5 / 11 LEU A  39
LEU A  23
LEU A  43
ALA A  52
LEU A  51
 LEU  A  39 ( 0.5A)
LEU  A  23 ( 0.6A)
LEU  A  43 ( 0.6A)
ALA  A  52 ( 0.0A)
LEU  A  51 ( 0.5A)
 1.13A 4wg0H-3s6fA:
undetectable
4wg0I-3s6fA:
undetectable
4wg0J-3s6fA:
undetectable		 4wg0H-3s6fA:
8.62
4wg0I-3s6fA:
8.62
4wg0J-3s6fA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		5 / 11 ALA A  52
LEU A  51
LEU A  43
LEU A  39
LEU A  23
 ALA  A  52 ( 0.0A)
LEU  A  51 ( 0.5A)
LEU  A  43 ( 0.6A)
LEU  A  39 ( 0.5A)
LEU  A  23 ( 0.6A)
 1.11A 4wg0G-3s6fA:
undetectable
4wg0H-3s6fA:
undetectable
4wg0I-3s6fA:
undetectable		 4wg0G-3s6fA:
8.62
4wg0H-3s6fA:
8.62
4wg0I-3s6fA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		5 / 11 LEU A  39
LEU A  23
LEU A  43
ALA A  52
LEU A  51
 LEU  A  39 ( 0.5A)
LEU  A  23 ( 0.6A)
LEU  A  43 ( 0.6A)
ALA  A  52 ( 0.0A)
LEU  A  51 ( 0.5A)
 1.11A 4wg0J-3s6fA:
undetectable
4wg0K-3s6fA:
undetectable
4wg0L-3s6fA:
undetectable		 4wg0J-3s6fA:
8.62
4wg0K-3s6fA:
8.62
4wg0L-3s6fA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		5 / 11 ALA A  52
LEU A  51
LEU A  43
LEU A  39
LEU A  23
 ALA  A  52 ( 0.0A)
LEU  A  51 ( 0.5A)
LEU  A  43 ( 0.6A)
LEU  A  39 ( 0.5A)
LEU  A  23 ( 0.6A)
 1.13A 4wg0I-3s6fA:
undetectable
4wg0J-3s6fA:
undetectable
4wg0K-3s6fA:
undetectable		 4wg0I-3s6fA:
8.62
4wg0J-3s6fA:
8.62
4wg0K-3s6fA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		5 / 11 ALA A  52
LEU A  51
LEU A  43
LEU A  39
LEU A  23
 ALA  A  52 ( 0.0A)
LEU  A  51 ( 0.5A)
LEU  A  43 ( 0.6A)
LEU  A  39 ( 0.5A)
LEU  A  23 ( 0.6A)
 1.11A 4wg0K-3s6fA:
undetectable
4wg0L-3s6fA:
undetectable
4wg0M-3s6fA:
undetectable		 4wg0K-3s6fA:
8.62
4wg0L-3s6fA:
8.62
4wg0M-3s6fA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		4 / 6 LEU A  66
ASN A  64
PRO A  76
ARG A 134
 LEU  A  66 ( 0.5A)
ASN  A  64 ( 0.6A)
PRO  A  76 ( 1.1A)
ARG  A 134 ( 0.6A)
 1.27A 4yv5B-3s6fA:
undetectable		 4yv5B-3s6fA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		4 / 6 LEU A  66
ASN A  64
PRO A  76
ARG A 134
 LEU  A  66 ( 0.5A)
ASN  A  64 ( 0.6A)
PRO  A  76 ( 1.1A)
ARG  A 134 ( 0.6A)
 1.27A 4yv5A-3s6fA:
undetectable		 4yv5A-3s6fA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 3s6f HYPOTHETICAL
ACETYLTRANSFERASE
(Deinococcus
radiodurans) 		5 / 9 LEU A  78
LEU A  89
GLY A  90
LEU A  93
ALA A  52
 LEU  A  78 (-0.5A)
LEU  A  89 (-0.5A)
GLY  A  90 (-0.0A)
LEU  A  93 ( 0.6A)
ALA  A  52 ( 0.0A)
 0.96A 5dqfA-3s6fA:
undetectable		 5dqfA-3s6fA:
12.90