SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s6i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DYR_A_TOPA407_1 (DIHYDROFOLATE REDUCTASE)	3s6i	DNA-3-METHYLADENINE GLYCOSYLASE 1 (Schizosaccharomy ces pombe)	5 / 11	ILE A 71 ALA A 100 ILE A 108 PHE A 103 ILE A 90	None	1.01A	1dyrA-3s6iA: undetectable	1dyrA-3s6iA: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXF_A_DZPA2001_1 (SERUM ALBUMIN)	3s6i	DNA-3-METHYLADENINE GLYCOSYLASE 1 (Schizosaccharomy ces pombe)	5 / 12	LEU A 54 LEU A 155 GLU A 136 LEU A 137 ARG A 140	None	1.21A	2bxfA-3s6iA: undetectable	2bxfA-3s6iA: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MBG_A_ACTA207_0 (FAD-LINKED SULFHYDRYL OXIDASE ALR)	3s6i	DNA-3-METHYLADENINE GLYCOSYLASE 1 (Schizosaccharomy ces pombe)	4 / 7	LEU A 193 ASP A 169 ARG A 149 ALA A 168	None	1.30A	3mbgA-3s6iA: undetectable 3mbgB-3s6iA: undetectable	3mbgA-3s6iA: 20.51 3mbgB-3s6iA: 20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G08_A_Z80A1187_1 (FREQUENIN 2)	3s6i	DNA-3-METHYLADENINE GLYCOSYLASE 1 (Schizosaccharomy ces pombe)	4 / 6	ILE A 71 PHE A 75 THR A 151 TRP A 150	None	1.32A	5g08A-3s6iA: undetectable	5g08A-3s6iA: 21.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DYR_A_TOPA407_1","DIHYDROFOLATE REDUCTASE","3s6i","DNA-3-METHYLADENINE GLYCOSYLASE 1","Schizosaccharomyces pombe",5,"ILE A  71;ALA A 100;ILE A 108;PHE A 103;ILE A  90","None","1.01A","1dyrA-3s6iA:undetectable","1dyrA-3s6iA:20.77"],["2BXF_A_DZPA2001_1","SERUM ALBUMIN","3s6i","DNA-3-METHYLADENINE GLYCOSYLASE 1","Schizosaccharomyces pombe",5,"LEU A  54;LEU A 155;GLU A 136;LEU A 137;ARG A 140","None","1.21A","2bxfA-3s6iA:undetectable","2bxfA-3s6iA:17.39"],["3MBG_A_ACTA207_0","FAD-LINKED SULFHYDRYL OXIDASE ALR","3s6i","DNA-3-METHYLADENINE GLYCOSYLASE 1","Schizosaccharomyces pombe",4,"LEU A 193;ASP A 169;ARG A 149;ALA A 168","None","1.30A","3mbgA-3s6iA:undetectable;3mbgB-3s6iA:undetectable","3mbgA-3s6iA:20.51;3mbgB-3s6iA:20.51"],["5G08_A_Z80A1187_1","FREQUENIN 2","3s6i","DNA-3-METHYLADENINE GLYCOSYLASE 1","Schizosaccharomyces pombe",4,"ILE A  71;PHE A  75;THR A 151;TRP A 150","None","1.32A","5g08A-3s6iA:undetectable","5g08A-3s6iA:21.95"]]