SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s6o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 ALA A  64
ASN A  43
PRO A  50
ALA A  51
 None
 0.91A 2ejfA-3s6oA:
undetectable		 2ejfA-3s6oA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		3 / 3 GLY A 167
ARG A 168
TYR A 165
 None
 0.80A 2opxA-3s6oA:
undetectable		 2opxA-3s6oA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_GLYA502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 HIS A 263
HIS A 127
TYR A 215
TYR A 190
 None
 1.27A 2vmyA-3s6oA:
undetectable
2vmyB-3s6oA:
undetectable		 2vmyA-3s6oA:
23.44
2vmyB-3s6oA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 ALA A  64
ASN A  43
PRO A  50
ALA A  51
 None
 0.87A 2zgwA-3s6oA:
undetectable		 2zgwA-3s6oA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		4 / 6 ALA A  64
ASN A  43
PRO A  50
ALA A  51
 None
 0.87A 2zgwB-3s6oA:
undetectable		 2zgwB-3s6oA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 LEU A 267
GLY A 268
ALA A 116
PHE A  91
LEU A 120
 None
 1.15A 3vywC-3s6oA:
undetectable		 3vywC-3s6oA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 HIS A 127
LEU A  56
ASN A 220
LEU A 217
GLY A 167
 None
 1.20A 4qckA-3s6oA:
undetectable		 4qckA-3s6oA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 ARG A 272
PHE A 101
TYR A 215
TYR A  37
LEU A  35
 None
 1.01A 5czyA-3s6oA:
undetectable		 5czyA-3s6oA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_1
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 SER A 187
TYR A 215
PHE A 101
HIS A 263
 None
 1.44A 5dlvB-3s6oA:
undetectable		 5dlvB-3s6oA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		3 / 3 GLY A 182
GLY A 181
GLN A 210
 None
 0.47A 5imsA-3s6oA:
undetectable		 5imsA-3s6oA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		3 / 3 GLU A  39
ARG A 265
TYR A  76
 None
 0.62A 5trqB-3s6oA:
undetectable		 5trqB-3s6oA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		5 / 10 ILE A 283
LEU A 280
PHE A 279
ASN A 220
LEU A  35
 None
 1.20A 5y7pB-3s6oA:
undetectable		 5y7pB-3s6oA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		5 / 10 ILE A 283
LEU A 280
PHE A 279
ASN A 220
LEU A  35
 None
 1.20A 5y7pD-3s6oA:
undetectable		 5y7pD-3s6oA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 3s6o POLYSACCHARIDE
DEACETYLASE FAMILY
PROTEIN
(Burkholderia
pseudomallei) 		3 / 3 HIS A 263
ASN A  36
LEU A  35
 None
 0.84A 6f7lB-3s6oA:
undetectable		 6f7lB-3s6oA:
23.01