SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s7i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		4 / 8 SER A 272
VAL A 247
LEU A 264
PRO A 267
 None
 0.95A 1fduB-3s7iA:
undetectable		 1fduB-3s7iA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		4 / 7 LEU A 433
MET A 431
LEU A 429
MET A 290
 None
 1.13A 1linA-3s7iA:
undetectable		 1linA-3s7iA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		5 / 12 VAL A 247
ILE A 274
LEU A 283
ILE A 238
ILE A 217
 None
 1.06A 1oipA-3s7iA:
undetectable		 1oipA-3s7iA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		3 / 3 ASP A 300
ARG A 185
ASP A 231
 None
 0.91A 1vptA-3s7iA:
undetectable		 1vptA-3s7iA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		5 / 12 GLY A 241
LEU A 258
GLU A 260
ILE A 274
VAL A 285
 None
 0.95A 2oxtC-3s7iA:
undetectable		 2oxtC-3s7iA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		3 / 3 ASN A 538
ALA A 535
LYS A 451
 None
 0.90A 3runA-3s7iA:
undetectable		 3runA-3s7iA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		3 / 3 HIS A 229
SER A 289
ASN A 293
 None
 0.81A 3s8pB-3s7iA:
undetectable		 3s8pB-3s7iA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		3 / 3 PHE A 301
VAL A 215
ILE A 193
 None
 0.54A 4emaA-3s7iA:
undetectable		 4emaA-3s7iA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		5 / 11 GLU A 466
ALA A 519
LEU A 504
LEU A 526
LEU A 528
 None
 0.83A 4wg0I-3s7iA:
undetectable
4wg0J-3s7iA:
undetectable
4wg0K-3s7iA:
undetectable		 4wg0I-3s7iA:
3.41
4wg0J-3s7iA:
3.41
4wg0K-3s7iA:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		5 / 11 ILE A 235
PHE A 531
ILE A 398
VAL A 285
VAL A 215
 None
 1.29A 5jkwA-3s7iA:
undetectable		 5jkwA-3s7iA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		5 / 9 ARG A 185
ILE A 238
ILE A 266
VAL A 215
ILE A 217
 None
 1.15A 5kr2D-3s7iA:
undetectable		 5kr2D-3s7iA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		5 / 12 ILE A 266
ASP A 300
VAL A 215
LEU A 264
LEU A 258
 None
 1.08A 6b54A-3s7iA:
undetectable		 6b54A-3s7iA:
20.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CB4_A_BEZA501_0
(CANAVALIN)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		4 / 8 HIS A 447
ASN A 449
VAL A 454
ARG A 540
 CL  A   1 (-4.3A)
CL  A   1 ( 4.4A)
None
CL  A   1 (-4.5A)
 0.37A 6cb4A-3s7iA:
46.2		 6cb4A-3s7iA:
39.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CB4_A_BEZA501_0
(CANAVALIN)		 3s7i ALLERGEN ARA H 1,
CLONE P41B
(Arachis
hypogaea) 		4 / 8 LEU A 528
HIS A 447
ASN A 449
VAL A 454
 None
CL  A   1 (-4.3A)
CL  A   1 ( 4.4A)
None
 0.70A 6cb4A-3s7iA:
46.2		 6cb4A-3s7iA:
39.70