SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s7z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		5 / 9 GLY A 192
THR A 194
ALA A  86
THR A 127
THR A 124
 None
SIN  A 300 (-3.3A)
None
None
SIN  A 300 (-4.0A)
 0.95A 1gtfD-3s7zA:
undetectable
1gtfE-3s7zA:
undetectable		 1gtfD-3s7zA:
12.92
1gtfE-3s7zA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		5 / 10 GLY A 192
THR A 194
ALA A  86
THR A 127
THR A 124
 None
SIN  A 300 (-3.3A)
None
None
SIN  A 300 (-4.0A)
 1.02A 1gtfJ-3s7zA:
undetectable
1gtfK-3s7zA:
undetectable		 1gtfJ-3s7zA:
12.92
1gtfK-3s7zA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		5 / 12 GLY A 192
THR A 194
ALA A  86
THR A 127
THR A 124
 None
SIN  A 300 (-3.3A)
None
None
SIN  A 300 (-4.0A)
 0.99A 1gtnL-3s7zA:
undetectable
1gtnV-3s7zA:
undetectable		 1gtnL-3s7zA:
12.92
1gtnV-3s7zA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		5 / 10 ALA A  86
THR A 127
THR A 124
GLY A 192
THR A 194
 None
None
SIN  A 300 (-4.0A)
None
SIN  A 300 (-3.3A)
 0.99A 1utdH-3s7zA:
undetectable
1utdI-3s7zA:
undetectable		 1utdH-3s7zA:
12.92
1utdI-3s7zA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		5 / 12 ALA A  86
THR A 127
THR A 124
GLY A 192
THR A 194
 None
None
SIN  A 300 (-4.0A)
None
SIN  A 300 (-3.3A)
 0.99A 1utdL-3s7zA:
undetectable
1utdM-3s7zA:
undetectable		 1utdL-3s7zA:
12.92
1utdM-3s7zA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		5 / 11 ALA A  86
THR A 127
THR A 124
GLY A 192
THR A 194
 None
None
SIN  A 300 (-4.0A)
None
SIN  A 300 (-3.3A)
 0.96A 1utdP-3s7zA:
undetectable
1utdQ-3s7zA:
undetectable		 1utdP-3s7zA:
12.92
1utdQ-3s7zA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		5 / 11 ALA A  86
THR A 127
THR A 124
GLY A 192
THR A 194
 None
None
SIN  A 300 (-4.0A)
None
SIN  A 300 (-3.3A)
 0.98A 1utdS-3s7zA:
undetectable
1utdT-3s7zA:
undetectable		 1utdS-3s7zA:
12.92
1utdT-3s7zA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		5 / 11 GLY A 192
THR A 194
ALA A  86
THR A 127
THR A 124
 None
SIN  A 300 (-3.3A)
None
None
SIN  A 300 (-4.0A)
 1.00A 1utdL-3s7zA:
undetectable
1utdV-3s7zA:
undetectable		 1utdL-3s7zA:
12.92
1utdV-3s7zA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		4 / 8 GLY A 165
THR A 168
ALA A 169
ALA A 170
 None
 0.49A 2ej3A-3s7zA:
undetectable		 2ej3A-3s7zA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		5 / 12 VAL A 155
LEU A 174
ILE A 178
ILE A 189
ALA A 186
 None
 1.18A 2gj5A-3s7zA:
undetectable		 2gj5A-3s7zA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		4 / 6 LEU A 218
THR A 215
PHE A  23
LEU A  26
 None
 1.12A 2wm3A-3s7zA:
3.2		 2wm3A-3s7zA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		5 / 12 ALA A 170
ILE A 178
VAL A 200
HIS A 203
ILE A 207
 None
 0.89A 4ax8A-3s7zA:
undetectable		 4ax8A-3s7zA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		5 / 12 ALA A 170
ILE A 178
VAL A 200
HIS A 203
ILE A 207
 None
 0.92A 4azvA-3s7zA:
undetectable		 4azvA-3s7zA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 3s7z PUTATIVE ASPARTATE
RACEMASE
(Salmonella
enterica) 		4 / 5 LEU A  53
ASP A  48
ARG A  49
ILE A  46
 None
None
SIN  A 300 (-3.8A)
None
 1.33A 4mwrA-3s7zA:
undetectable		 4mwrA-3s7zA:
20.78