SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)
3s84 APOLIPOPROTEIN A-IV
(Homo
sapiens)
4 / 4 LEU A 238
SER A 222
LEU A 329
LEU A 325
None
1.10A 1yajA-3s84A:
undetectable
1yajA-3s84A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)
3s84 APOLIPOPROTEIN A-IV
(Homo
sapiens)
4 / 5 LEU A 238
SER A 222
LEU A 329
LEU A 325
None
1.08A 1yajD-3s84A:
undetectable
1yajD-3s84A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)
3s84 APOLIPOPROTEIN A-IV
(Homo
sapiens)
4 / 5 ASP A 206
THR A 202
GLU A 250
LYS A 209
None
1.03A 4a3pA-3s84A:
undetectable
4a3pA-3s84A:
20.79