SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s8i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3s8i PROTEIN DDI1 HOMOLOG
1
(Homo
sapiens) 		5 / 10 ALA A 263
LEU A 329
MET A 328
ILE A 246
LEU A 335
 None
 1.41A 1a52A-3s8iA:
undetectable		 1a52A-3s8iA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 3s8i PROTEIN DDI1 HOMOLOG
1
(Homo
sapiens) 		5 / 10 ALA A 263
LEU A 329
MET A 328
ILE A 246
LEU A 335
 None
 1.45A 1qkuA-3s8iA:
undetectable		 1qkuA-3s8iA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 3s8i PROTEIN DDI1 HOMOLOG
1
(Homo
sapiens) 		5 / 10 ALA A 263
LEU A 329
MET A 328
ILE A 246
LEU A 335
 None
 1.44A 1qkuB-3s8iA:
undetectable		 1qkuB-3s8iA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 3s8i PROTEIN DDI1 HOMOLOG
1
(Homo
sapiens) 		5 / 10 ALA A 263
LEU A 329
MET A 328
ILE A 246
LEU A 335
 None
 1.46A 1qkuC-3s8iA:
undetectable		 1qkuC-3s8iA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 3s8i PROTEIN DDI1 HOMOLOG
1
(Homo
sapiens) 		4 / 6 SER A 319
ILE A 298
ALA A 290
ALA A 263
 None
 0.95A 1w0gA-3s8iA:
undetectable		 1w0gA-3s8iA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3s8i PROTEIN DDI1 HOMOLOG
1
(Homo
sapiens) 		5 / 12 GLY A 252
VAL A 302
SER A 269
MET A 328
LEU A 255
 None
 1.25A 4a83A-3s8iA:
undetectable		 4a83A-3s8iA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 3s8i PROTEIN DDI1 HOMOLOG
1
(Homo
sapiens) 		3 / 3 SER A 319
MET A 265
ASP A 323
 None
 0.98A 4mm4B-3s8iA:
undetectable		 4mm4B-3s8iA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3s8i PROTEIN DDI1 HOMOLOG
1
(Homo
sapiens) 		5 / 12 PHE A 318
ALA A 305
LEU A 281
MET A 279
LEU A 255
 None
 1.05A 5m24A-3s8iA:
undetectable		 5m24A-3s8iA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 3s8i PROTEIN DDI1 HOMOLOG
1
(Homo
sapiens) 		5 / 10 ALA A 263
LEU A 329
MET A 328
ILE A 246
LEU A 335
 None
 1.44A 6cbzB-3s8iA:
undetectable		 6cbzB-3s8iA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 3s8i PROTEIN DDI1 HOMOLOG
1
(Homo
sapiens) 		4 / 5 ILE A 246
GLN A 357
THR A 358
LEU A 344
 None
 1.05A 6f3mD-3s8iA:
undetectable		 6f3mD-3s8iA:
16.51