SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s8m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		4 / 8 LEU A 317
GLY A 264
LEU A 135
TYR A 318
 None
 0.96A 1jlbA-3s8mA:
undetectable		 1jlbA-3s8mA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.76A 1muiB-3s8mA:
undetectable		 1muiB-3s8mA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 11 GLN A 179
ILE A 231
ALA A 167
VAL A 284
VAL A 355
 None
 1.16A 1n4hA-3s8mA:
undetectable		 1n4hA-3s8mA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 ALA A  62
GLY A  64
ILE A  28
ALA A  98
PHE A  94
 None
 1.20A 1ve3A-3s8mA:
6.0		 1ve3A-3s8mA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 ALA A  62
GLY A  64
ILE A  28
ALA A  98
PHE A  94
 None
 1.14A 1ve3B-3s8mA:
6.2		 1ve3B-3s8mA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 10 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.86A 2aquA-3s8mA:
undetectable		 2aquA-3s8mA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 11 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.87A 2aquB-3s8mA:
undetectable		 2aquB-3s8mA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.74A 2avvB-3s8mA:
undetectable		 2avvB-3s8mA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 9 LEU A 209
ARG A 118
LEU A  45
LEU A  70
ALA A 117
 None
 1.31A 2bxeA-3s8mA:
undetectable		 2bxeA-3s8mA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.77A 2fxeA-3s8mA:
undetectable		 2fxeA-3s8mA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 11 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.86A 2fxeB-3s8mA:
undetectable		 2fxeB-3s8mA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1291_1
(FICOLIN-2)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		4 / 4 ASP A 115
LEU A 147
GLY A 149
ARG A 145
 None
 1.44A 2j2pD-3s8mA:
undetectable
2j2pE-3s8mA:
undetectable		 2j2pD-3s8mA:
18.10
2j2pE-3s8mA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.81A 2o4kB-3s8mA:
undetectable		 2o4kB-3s8mA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.80A 2r5pD-3s8mA:
undetectable		 2r5pD-3s8mA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 11 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.88A 2r5qB-3s8mA:
undetectable		 2r5qB-3s8mA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		4 / 8 GLY A  87
ILE A 306
VAL A 274
SER A  91
 None
 0.90A 2yoeB-3s8mA:
undetectable
2yoeC-3s8mA:
undetectable		 2yoeB-3s8mA:
21.23
2yoeC-3s8mA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.89A 2z54B-3s8mA:
undetectable		 2z54B-3s8mA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 11 LEU A 135
ALA A  67
ALA A  61
VAL A 222
LEU A 312
 None
 1.30A 3bszE-3s8mA:
undetectable		 3bszE-3s8mA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.87A 3bvbA-3s8mA:
undetectable		 3bvbA-3s8mA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 10 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.90A 3ekyA-3s8mA:
undetectable		 3ekyA-3s8mA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		4 / 8 LEU A 312
GLY A  64
ALA A  62
THR A  69
 None
 0.79A 3jusA-3s8mA:
undetectable		 3jusA-3s8mA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		4 / 8 LEU A 312
GLY A  64
ALA A  62
THR A  69
 None
 0.79A 3jusA-3s8mA:
undetectable		 3jusA-3s8mA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.88A 3jw2A-3s8mA:
undetectable		 3jw2A-3s8mA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.82A 3lzsA-3s8mA:
undetectable		 3lzsA-3s8mA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.84A 3lzuA-3s8mA:
undetectable		 3lzuA-3s8mA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.82A 3pwmA-3s8mA:
undetectable		 3pwmA-3s8mA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A  54
GLY A  87
GLN A  27
VAL A  24
PHE A  73
 None
 1.23A 3qowA-3s8mA:
3.8		 3qowA-3s8mA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		4 / 6 SER A 105
LEU A 103
THR A  69
ARG A  58
 None
 1.39A 3thrB-3s8mA:
5.8		 3thrB-3s8mA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.82A 3tkwA-3s8mA:
undetectable		 3tkwA-3s8mA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.71A 4hlaA-3s8mA:
undetectable		 4hlaA-3s8mA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 11 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.72A 4hlaB-3s8mA:
undetectable		 4hlaB-3s8mA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		3 / 4 SER A 279
GLY A 304
GLU A  26
 None
 0.57A 4juoA-3s8mA:
undetectable
4juoC-3s8mA:
2.5		 4juoA-3s8mA:
22.82
4juoC-3s8mA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		4 / 6 GLU A 326
ARG A 334
ASP A 337
ASP A 336
 None
 1.30A 4kcnA-3s8mA:
undetectable		 4kcnA-3s8mA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		4 / 6 GLU A 326
ARG A 334
ASP A 337
ASP A 336
 None
 1.28A 4kcnB-3s8mA:
undetectable		 4kcnB-3s8mA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 VAL A 268
ASN A 267
ARG A 220
TYR A 318
LEU A 312
 None
 1.29A 4po0A-3s8mA:
undetectable		 4po0A-3s8mA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		4 / 5 PRO A 283
ALA A 169
ALA A 180
ILE A 178
 None
 0.80A 5jncD-3s8mA:
undetectable		 5jncD-3s8mA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 LEU A 317
LEU A 333
LEU A 135
ALA A 252
LEU A 259
 None
 1.14A 5og9B-3s8mA:
undetectable		 5og9B-3s8mA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		4 / 8 GLY A  71
ILE A 108
ASP A  95
ASP A 397
 None
 0.94A 6ag0A-3s8mA:
undetectable		 6ag0A-3s8mA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.87A 6dgxA-3s8mA:
undetectable		 6dgxA-3s8mA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		5 / 12 GLY A 213
ALA A 212
ILE A 206
VAL A 121
ILE A 122
 None
 0.81A 6dj1A-3s8mA:
undetectable		 6dj1A-3s8mA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3s8m ENOYL-ACP REDUCTASE
(Xanthomonas
oryzae) 		4 / 5 ILE A 289
ALA A 278
LEU A 376
LYS A  12
 None
 0.90A 6dwnA-3s8mA:
undetectable		 6dwnA-3s8mA:
11.69