SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s97'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3s97 CONTACTIN-1
(Homo
sapiens) 		4 / 6 LEU C 266
PRO C 271
ALA C 312
ALA C 293
 None
 0.98A 2vcvK-3s97C:
undetectable		 2vcvK-3s97C:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 3s97 CONTACTIN-1
(Homo
sapiens) 		5 / 12 ILE C 218
PRO C 165
LEU C 135
LEU C 168
VAL C 213
 None
 1.26A 5im2A-3s97C:
undetectable		 5im2A-3s97C:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 3s97 CONTACTIN-1
(Homo
sapiens) 		3 / 3 LYS C 133
SER C 215
SER C 217
 None
 0.84A 6gbfA-3s97C:
undetectable		 6gbfA-3s97C:
20.61