SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		3 / 3 TRP A 143
TYR A 171
LEU A 108
 NAG  A 307 (-4.1A)
None
None
 0.96A 1kxhA-3s98A:
undetectable		 1kxhA-3s98A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 7 LYS A 220
LEU A 219
GLN A 263
LEU A 278
 None
 1.07A 1v55C-3s98A:
undetectable
1v55J-3s98A:
undetectable		 1v55C-3s98A:
20.62
1v55J-3s98A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		5 / 7 LYS A 220
LEU A 219
GLN A 263
LEU A 278
PHE A 297
 None
 1.20A 2dysC-3s98A:
undetectable
2dysJ-3s98A:
undetectable		 2dysC-3s98A:
20.62
2dysJ-3s98A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 7 LYS A 220
LEU A 219
GLN A 263
LEU A 278
 None
 1.05A 2dysP-3s98A:
undetectable
2dysW-3s98A:
undetectable		 2dysP-3s98A:
20.62
2dysW-3s98A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 7 LYS A 220
LEU A 219
GLN A 263
LEU A 278
 None
 1.09A 2eimC-3s98A:
undetectable
2eimJ-3s98A:
undetectable		 2eimC-3s98A:
20.62
2eimJ-3s98A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		5 / 7 LYS A 220
LEU A 219
GLN A 263
LEU A 278
PHE A 297
 None
 1.20A 2zxwC-3s98A:
undetectable
2zxwJ-3s98A:
undetectable		 2zxwC-3s98A:
20.62
2zxwJ-3s98A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_A_9PLA1_1
(CYTOCHROME P450 2A13)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		5 / 9 PHE A 266
PHE A 297
ASN A 269
PHE A 271
THR A 299
 None
 1.30A 3t3sA-3s98A:
undetectable		 3t3sA-3s98A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 8 PHE A 266
PHE A 297
ASN A 269
PHE A 271
 None
 0.87A 3t3sF-3s98A:
undetectable		 3t3sF-3s98A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 4 PHE A  96
VAL A  69
ALA A  99
PHE A  62
 None
 1.28A 4f3tA-3s98A:
undetectable		 4f3tA-3s98A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 5 PHE A  96
VAL A  69
ALA A  99
PHE A  62
 None
 1.28A 4w5oA-3s98A:
undetectable		 4w5oA-3s98A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 4 PHE A  96
VAL A  69
ALA A  99
PHE A  62
 None
 1.27A 4w5qA-3s98A:
undetectable		 4w5qA-3s98A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 4 PHE A  96
VAL A  69
ALA A  99
PHE A  62
 None
 1.28A 4w5rA-3s98A:
undetectable		 4w5rA-3s98A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 4 PHE A  96
VAL A  69
ALA A  99
PHE A  62
 None
 1.29A 4w5tA-3s98A:
undetectable		 4w5tA-3s98A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 5 PHE A  96
VAL A  69
ALA A  99
PHE A  62
 None
 1.28A 4z4cA-3s98A:
undetectable		 4z4cA-3s98A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 5 PHE A  96
VAL A  69
ALA A  99
PHE A  62
 None
 1.29A 4z4dA-3s98A:
undetectable		 4z4dA-3s98A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 5 PHE A  96
VAL A  69
ALA A  99
PHE A  62
 None
 1.29A 4z4eA-3s98A:
undetectable		 4z4eA-3s98A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 4 PHE A  96
VAL A  69
ALA A  99
PHE A  62
 None
 1.27A 4z4gA-3s98A:
undetectable		 4z4gA-3s98A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3s98 INTERFERON
ALPHA/BETA RECEPTOR
1
(Homo
sapiens) 		4 / 4 PHE A  96
VAL A  69
ALA A  99
PHE A  62
 None
 1.27A 5ki6A-3s98A:
undetectable		 5ki6A-3s98A:
15.85