SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 3s9f TRYPAREDOXIN
(Leishmania
major) 		3 / 3 TRP A  70
ALA A  99
VAL A  97
 None
 0.95A 1c4dA-3s9fA:
undetectable
1c4dB-3s9fA:
undetectable		 1c4dA-3s9fA:
4.85
1c4dB-3s9fA:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3s9f TRYPAREDOXIN
(Leishmania
major) 		4 / 6 ILE A  66
THR A  20
PHE A  77
TYR A  81
 None
None
MG  A 147 ( 4.9A)
None
 1.25A 3elzB-3s9fA:
undetectable		 3elzB-3s9fA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 3s9f TRYPAREDOXIN
(Leishmania
major) 		4 / 8 ARG A  15
SER A  69
PHE A  91
ASP A  76
 MG  A 147 (-4.4A)
None
None
None
 1.25A 3jq7B-3s9fA:
undetectable		 3jq7B-3s9fA:
26.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 3s9f TRYPAREDOXIN
(Leishmania
major) 		4 / 6 ARG A  15
SER A  69
PHE A  91
ASP A  76
 MG  A 147 (-4.4A)
None
None
None
 1.24A 3jqaA-3s9fA:
undetectable		 3jqaA-3s9fA:
26.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 3s9f TRYPAREDOXIN
(Leishmania
major) 		4 / 6 ARG A  15
SER A  69
PHE A  91
ASP A  76
 MG  A 147 (-4.4A)
None
None
None
 1.24A 3jqaB-3s9fA:
undetectable		 3jqaB-3s9fA:
26.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 3s9f TRYPAREDOXIN
(Leishmania
major) 		4 / 6 ARG A  15
SER A  69
PHE A  91
ASP A  76
 MG  A 147 (-4.4A)
None
None
None
 1.28A 3jqaC-3s9fA:
undetectable		 3jqaC-3s9fA:
26.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 3s9f TRYPAREDOXIN
(Leishmania
major) 		4 / 6 ARG A  15
SER A  69
PHE A  91
ASP A  76
 MG  A 147 (-4.4A)
None
None
None
 1.29A 3jqaD-3s9fA:
undetectable		 3jqaD-3s9fA:
26.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 3s9f TRYPAREDOXIN
(Leishmania
major) 		4 / 6 LEU A  14
LEU A  12
ASN A  93
ILE A  96
 None
None
MG  A 148 (-4.2A)
MG  A 148 (-4.5A)
 0.89A 4ww7A-3s9fA:
undetectable		 4ww7A-3s9fA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3s9f TRYPAREDOXIN
(Leishmania
major) 		3 / 3 GLY A  28
THR A  30
ASN A  62
 None
 0.60A 5odiG-3s9fA:
undetectable		 5odiG-3s9fA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3s9f TRYPAREDOXIN
(Leishmania
major) 		3 / 3 LEU A 131
GLN A  49
LYS A  61
 None
 0.61A 6exiB-3s9fA:
undetectable		 6exiB-3s9fA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 3s9f TRYPAREDOXIN
(Leishmania
major) 		3 / 3 LEU A 131
GLN A  49
LYS A  61
 None
 0.60A 6exiA-3s9fA:
undetectable		 6exiA-3s9fA:
22.22