SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 3s9x ASCH DOMAIN
(Vibrio
cholerae) 		4 / 8 GLU A 109
PHE A 126
PHE A 127
HIS A 123
 None
 0.99A 1ax9A-3s9xA:
undetectable		 1ax9A-3s9xA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 3s9x ASCH DOMAIN
(Vibrio
cholerae) 		5 / 11 LEU A  74
TYR A 153
PHE A   8
LEU A   9
GLU A  89
 None
 1.34A 3bgrA-3s9xA:
undetectable
3bgrB-3s9xA:
undetectable		 3bgrA-3s9xA:
13.39
3bgrB-3s9xA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IEO_A_AMJA300_0
(CARBONIC ANHYDRASE 2)		 3s9x ASCH DOMAIN
(Vibrio
cholerae) 		4 / 4 ILE A  88
GLN A  75
VAL A  77
PHE A 149
 None
 1.18A 3ieoA-3s9xA:
undetectable		 3ieoA-3s9xA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_1
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 3s9x ASCH DOMAIN
(Vibrio
cholerae) 		4 / 4 SER A  28
GLU A 147
GLU A 109
ASP A  30
 None
 0.99A 4pclB-3s9xA:
undetectable		 4pclB-3s9xA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 3s9x ASCH DOMAIN
(Vibrio
cholerae) 		5 / 12 LEU A  74
TYR A 153
PRO A  84
PHE A   8
LEU A   9
 None
 1.35A 6eliA-3s9xA:
undetectable		 6eliA-3s9xA:
16.88