SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3saj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		5 / 12 MET A  52
TYR A  71
THR A  75
LEU A  79
PHE A  90
 None
 1.49A 2mjiA-3sajA:
undetectable		 2mjiA-3sajA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1161_1
(ALLERGEN ARG R 1)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		4 / 4 VAL A 232
TYR A 210
VAL A 199
SER A 228
 None
 1.47A 2x45B-3sajA:
undetectable		 2x45B-3sajA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		3 / 3 TYR A 167
VAL A 157
THR A 163
 None
 0.89A 2ygnA-3sajA:
undetectable		 2ygnA-3sajA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		5 / 12 ALA A 246
GLY A 330
GLY A 333
ARG A 247
ASP A 242
 None
 1.08A 3m6vA-3sajA:
3.6		 3m6vA-3sajA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		5 / 12 ALA A 246
GLY A 330
GLY A 333
ARG A 247
ASP A 242
 None
 1.09A 3m6vB-3sajA:
2.0		 3m6vB-3sajA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		6 / 12 LEU A 289
GLY A 316
GLY A  63
VAL A  64
PRO A   4
ILE A 296
 None
 1.32A 3nu5A-3sajA:
undetectable		 3nu5A-3sajA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		5 / 12 GLY A  69
PHE A  90
ASN A  45
MET A  78
LEU A  79
 None
None
NAG  A 600 (-1.9A)
None
None
 1.47A 4a83A-3sajA:
undetectable		 4a83A-3sajA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		4 / 7 VAL A 281
MET A 282
ALA A 285
PHE A 286
 None
 0.91A 4lb2A-3sajA:
undetectable		 4lb2A-3sajA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		3 / 3 ASP A 185
ASN A 158
SER A 188
 None
 0.78A 4obwA-3sajA:
4.0		 4obwA-3sajA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		4 / 5 LEU A 212
PHE A 235
ILE A 211
ILE A 118
 None
 1.09A 5dzk4-3sajA:
undetectable
5dzkg-3sajA:
undetectable
5dzkm-3sajA:
undetectable
5dzkn-3sajA:
undetectable		 5dzk4-3sajA:
4.76
5dzkg-3sajA:
20.58
5dzkm-3sajA:
19.49
5dzkn-3sajA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		5 / 10 GLY A 278
ALA A 285
VAL A 281
GLU A 284
ILE A  91
 None
 1.04A 5i3cB-3sajA:
undetectable		 5i3cB-3sajA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		5 / 11 GLY A 278
ALA A 285
VAL A 281
GLU A 284
ILE A  91
 None
 1.17A 5i3cC-3sajA:
undetectable		 5i3cC-3sajA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		4 / 8 THR A 347
TYR A 346
ARG A 327
GLN A 336
 None
None
NAG  A 800 ( 3.1A)
NAG  A 800 (-3.1A)
 1.20A 5tzoB-3sajA:
undetectable		 5tzoB-3sajA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		4 / 8 THR A 347
TYR A 346
ARG A 327
GLN A 336
 None
None
NAG  A 800 ( 3.1A)
NAG  A 800 (-3.1A)
 1.22A 5tzoC-3sajA:
undetectable		 5tzoC-3sajA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		5 / 12 PHE A  13
GLY A  69
GLY A  11
ILE A   9
LEU A  31
 None
 1.19A 5ul4A-3sajA:
7.6		 5ul4A-3sajA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		4 / 8 HIS A 209
ASN A 231
HIS A 355
GLU A 352
 NAG  A 700 (-4.2A)
NAG  A 700 (-1.9A)
None
None
 1.15A 6b94A-3sajA:
undetectable		 6b94A-3sajA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3saj GLUTAMATE RECEPTOR 1
(Rattus
norvegicus) 		3 / 3 PHE A 328
ARG A 343
ALA A 273
 None
 0.92A 6ecfB-3sajA:
3.1		 6ecfB-3sajA:
21.04