SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sao'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MX8_A_RTLA135_0 (CELLULAR RETINOL-BINDING PROTEIN I, HOLO)	3sao	EXTRACELLULAR FATTY ACID-BINDING PROTEIN (Gallus gallus)	5 / 12	PHE A 24 ALA A 143 TYR A 114 PHE A 65 ILE A 14	None None NKN A 161 (-4.0A) NKN A 161 (-4.6A) None	1.25A	1mx8A-3saoA: 5.6	1mx8A-3saoA: 22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D7H_A_H4BA902_1 (NITRIC OXIDE SYNTHASE OXYGENASE)	3sao	EXTRACELLULAR FATTY ACID-BINDING PROTEIN (Gallus gallus)	3 / 3	ARG A 112 THR A 63 TRP A 61	NKN A 161 (-3.9A) None None	1.23A	4d7hA-3saoA: undetectable	4d7hA-3saoA: 19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1G_A_LNLA701_2 (PROSTAGLANDIN G/H SYNTHASE 2)	3sao	EXTRACELLULAR FATTY ACID-BINDING PROTEIN (Gallus gallus)	4 / 5	ARG A 116 VAL A 48 LEU A 46 SER A 39	None	1.01A	4e1gA-3saoA: undetectable	4e1gA-3saoA: 13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UG5_A_H4BA902_1 (NITRIC OXIDE SYNTHASE OXYGENASE)	3sao	EXTRACELLULAR FATTY ACID-BINDING PROTEIN (Gallus gallus)	3 / 3	ARG A 112 THR A 63 TRP A 61	NKN A 161 (-3.9A) None None	1.19A	4ug5A-3saoA: undetectable	4ug5A-3saoA: 19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6C_A_H4BA902_1 (NITRIC OXIDE SYNTHASE OXYGENASE)	3sao	EXTRACELLULAR FATTY ACID-BINDING PROTEIN (Gallus gallus)	3 / 3	ARG A 112 THR A 63 TRP A 61	NKN A 161 (-3.9A) None None	1.19A	5g6cA-3saoA: undetectable	5g6cA-3saoA: 21.13

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MX8_A_RTLA135_0","CELLULAR RETINOL-BINDING PROTEIN I, HOLO","3sao","EXTRACELLULAR FATTY ACID-BINDING PROTEIN","Gallus gallus",5,"PHE A  24;ALA A 143;TYR A 114;PHE A  65;ILE A  14","None;None;NKN A 161 (-4.0A);NKN A 161 (-4.6A);None","1.25A","1mx8A-3saoA:5.6","1mx8A-3saoA:22.93"],["4D7H_A_H4BA902_1","NITRIC OXIDE SYNTHASE OXYGENASE","3sao","EXTRACELLULAR FATTY ACID-BINDING PROTEIN","Gallus gallus",3,"ARG A 112;THR A  63;TRP A  61","NKN A 161 (-3.9A);None;None","1.23A","4d7hA-3saoA:undetectable","4d7hA-3saoA:19.72"],["4E1G_A_LNLA701_2","PROSTAGLANDIN G\/H SYNTHASE 2","3sao","EXTRACELLULAR FATTY ACID-BINDING PROTEIN","Gallus gallus",4,"ARG A 116;VAL A  48;LEU A  46;SER A  39","None","1.01A","4e1gA-3saoA:undetectable","4e1gA-3saoA:13.60"],["4UG5_A_H4BA902_1","NITRIC OXIDE SYNTHASE OXYGENASE","3sao","EXTRACELLULAR FATTY ACID-BINDING PROTEIN","Gallus gallus",3,"ARG A 112;THR A  63;TRP A  61","NKN A 161 (-3.9A);None;None","1.19A","4ug5A-3saoA:undetectable","4ug5A-3saoA:19.72"],["5G6C_A_H4BA902_1","NITRIC OXIDE SYNTHASE OXYGENASE","3sao","EXTRACELLULAR FATTY ACID-BINDING PROTEIN","Gallus gallus",3,"ARG A 112;THR A  63;TRP A  61","NKN A 161 (-3.9A);None;None","1.19A","5g6cA-3saoA:undetectable","5g6cA-3saoA:21.13"]]