SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sbg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 12 ILE A2207
PHE A2206
LEU A2226
THR A2276
LEU A2280
 None
 1.07A 1og5B-3sbgA:
undetectable		 1og5B-3sbgA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 PRO A1958
LYS A1833
MET A1835
GLU A1842
 None
 1.48A 1qhyA-3sbgA:
undetectable		 1qhyA-3sbgA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		3 / 3 GLU A2052
TRP A2048
LYS A2279
 None
 1.23A 1qu2A-3sbgA:
undetectable		 1qu2A-3sbgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 LEU A2012
LEU A2011
ILE A2034
SER A2042
 None
 1.13A 2hc4A-3sbgA:
undetectable		 2hc4A-3sbgA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 8 ILE A2293
ILE A2259
ILE A2289
VAL A2224
 None
 0.66A 2nniA-3sbgA:
undetectable		 2nniA-3sbgA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_3
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 12 ILE A1954
GLY A1833
ASN A1839
LEU A1843
VAL A1935
 None
 1.45A 2nyrB-3sbgA:
undetectable		 2nyrB-3sbgA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 8 VAL A2227
PRO A2228
PRO A2352
SER A2353
 None
 0.96A 2v32C-3sbgA:
2.2
2v32D-3sbgA:
undetectable		 2v32C-3sbgA:
17.76
2v32D-3sbgA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 8 LEU A1882
PHE A1965
THR A2009
ALA A1968
 None
 1.02A 3ax9B-3sbgA:
undetectable		 3ax9B-3sbgA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 10 PHE A2005
PHE A1844
THR A1959
ILE A1934
PHE A1851
 None
 1.25A 3t3qB-3sbgA:
undetectable		 3t3qB-3sbgA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 10 PHE A2005
PHE A1844
THR A1959
ILE A1934
PHE A1851
 None
 1.22A 3t3qC-3sbgA:
undetectable		 3t3qC-3sbgA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 10 PHE A2005
PHE A1844
THR A1959
ILE A1934
PHE A1851
 None
 1.25A 3t3qD-3sbgA:
undetectable		 3t3qD-3sbgA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL A2274
TRP A2314
PHE A2329
GLU A2310
 None
 1.26A 3ufrA-3sbgA:
undetectable
3ufrB-3sbgA:
undetectable		 3ufrA-3sbgA:
21.60
3ufrB-3sbgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		3 / 3 ARG A2388
ARG A2153
TRP A2152
 None
 1.14A 4b7nA-3sbgA:
undetectable		 4b7nA-3sbgA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		3 / 3 ARG A2388
ARG A2153
TRP A2152
 None
 1.21A 4cpzC-3sbgA:
undetectable		 4cpzC-3sbgA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		3 / 3 ARG A2388
ARG A2153
TRP A2152
 None
 1.09A 4cpzE-3sbgA:
undetectable		 4cpzE-3sbgA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		3 / 3 ARG A2388
ARG A2153
TRP A2152
 None
 1.14A 4cpzF-3sbgA:
undetectable		 4cpzF-3sbgA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		3 / 3 ARG A2388
ARG A2153
TRP A2152
 None
 1.11A 4cpzG-3sbgA:
undetectable		 4cpzG-3sbgA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		3 / 3 ARG A2388
ARG A2153
TRP A2152
 None
 1.19A 4cpzH-3sbgA:
undetectable		 4cpzH-3sbgA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 PHE A2329
ASN A2318
ALA A2275
LEU A2307
 None
 0.99A 4ejgD-3sbgA:
undetectable		 4ejgD-3sbgA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 ILE A2259
VAL A2184
PHE A2349
ASP A2343
 None
 1.06A 4iarA-3sbgA:
undetectable		 4iarA-3sbgA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 SER A2197
ASN A2159
PHE A2382
TRP A2357
 None
 1.43A 4kcnB-3sbgA:
undetectable		 4kcnB-3sbgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 8 ILE A2207
VAL A2171
LEU A2302
ILE A2169
 None
 0.80A 4r38A-3sbgA:
undetectable		 4r38A-3sbgA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 7 VAL A2274
TRP A2314
PHE A2329
GLU A2310
 None
 1.25A 4v3uC-3sbgA:
undetectable
4v3uD-3sbgA:
undetectable		 4v3uC-3sbgA:
22.26
4v3uD-3sbgA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 6 VAL A2274
TRP A2314
PHE A2329
GLU A2310
 None
 1.30A 4v3wA-3sbgA:
undetectable
4v3wB-3sbgA:
undetectable		 4v3wA-3sbgA:
21.60
4v3wB-3sbgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 12 LEU A2015
LEU A2012
TRP A1995
LEU A1889
LEU A2039
 None
 1.00A 5mwyA-3sbgA:
undetectable		 5mwyA-3sbgA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3sbg PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 12 TRP A2258
THR A2276
VAL A2274
SER A2326
ASN A2323
 None
 1.36A 6h7jA-3sbgA:
undetectable		 6h7jA-3sbgA:
7.10