SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sbq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 HIS A 130
HIS A 178
HIS A 129
HIS A 326
 CUK  A 702 (-3.2A)
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
CUK  A 702 (-3.1A)
 0.98A 1azmA-3sbqA:
undetectable		 1azmA-3sbqA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 HIS A 130
HIS A 178
HIS A 129
HIS A 326
 CUK  A 702 (-3.2A)
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
CUK  A 702 (-3.1A)
 0.99A 1bzmA-3sbqA:
undetectable		 1bzmA-3sbqA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		5 / 6 HIS A 130
HIS A 178
HIS A 326
HIS A 382
HIS A 433
 CUK  A 702 (-3.2A)
CUK  A 702 (-3.1A)
CUK  A 702 (-3.1A)
CUK  A 702 ( 3.3A)
CUK  A 702 (-3.1A)
 1.33A 1fweC-3sbqA:
undetectable		 1fweC-3sbqA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 GLU A 492
HIS A 494
HIS A  78
 None
CUK  A 702 (-3.3A)
None
 0.43A 1oe2A-3sbqA:
8.2		 1oe2A-3sbqA:
20.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IWK_A_CUA1598_0
(NITROUS OXIDE
REDUCTASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 HIS A 583
CYH A 618
CYH A 622
MET A 629
 CUA  A 701 (-4.3A)
CUA  A 701 (-2.2A)
CUA  A 701 (-2.3A)
CUA  A 701 (-2.3A)
 0.44A 2iwkA-3sbqA:
64.2		 2iwkA-3sbqA:
56.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 CYH A 618
CYH A 622
HIS A 626
 CUA  A 701 (-2.2A)
CUA  A 701 (-2.3A)
CUA  A 701 (-3.0A)
 0.11A 2iwkA-3sbqA:
64.2		 2iwkA-3sbqA:
56.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IWK_B_CUB1598_0
(NITROUS OXIDE
REDUCTASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 HIS A 583
CYH A 618
CYH A 622
MET A 629
 CUA  A 701 (-4.3A)
CUA  A 701 (-2.2A)
CUA  A 701 (-2.3A)
CUA  A 701 (-2.3A)
 0.42A 2iwkB-3sbqA:
64.2		 2iwkB-3sbqA:
56.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 CYH A 618
CYH A 622
HIS A 626
 CUA  A 701 (-2.2A)
CUA  A 701 (-2.3A)
CUA  A 701 (-3.0A)
 0.12A 2iwkB-3sbqA:
64.2		 2iwkB-3sbqA:
56.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.73A 2y69N-3sbqA:
undetectable		 2y69N-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 ALA A 251
TYR A 219
ILE A 280
TYR A 190
 None
 0.99A 2zm8A-3sbqA:
undetectable		 2zm8A-3sbqA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 ALA A 251
TYR A 219
ILE A 280
TYR A 190
 None
 0.99A 2zmaA-3sbqA:
undetectable		 2zmaA-3sbqA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.78A 2zxwN-3sbqA:
undetectable		 2zxwN-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.74A 3abmN-3sbqA:
undetectable		 3abmN-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.75A 3ag1N-3sbqA:
undetectable		 3ag1N-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.73A 3ag4N-3sbqA:
undetectable		 3ag4N-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.73A 3asnA-3sbqA:
undetectable		 3asnA-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.76A 3asnN-3sbqA:
undetectable		 3asnN-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.73A 3asoA-3sbqA:
undetectable		 3asoA-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.76A 3asoN-3sbqA:
undetectable		 3asoN-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 ARG A 114
GLY A 108
VAL A 101
LEU A 124
 None
 1.04A 3bgdB-3sbqA:
undetectable		 3bgdB-3sbqA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 5 HIS A 129
HIS A 494
ASP A 127
HIS A  78
 CUK  A 702 (-3.5A)
CUK  A 702 (-3.3A)
None
None
 1.02A 3c0zA-3sbqA:
undetectable		 3c0zA-3sbqA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 6 HIS A 129
HIS A 494
ASP A 127
HIS A  78
 CUK  A 702 (-3.5A)
CUK  A 702 (-3.3A)
None
None
 1.04A 3c0zC-3sbqA:
undetectable		 3c0zC-3sbqA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1004_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 HIS A 583
CYH A 618
CYH A 622
MET A 629
 CUA  A 701 (-4.3A)
CUA  A 701 (-2.2A)
CUA  A 701 (-2.3A)
CUA  A 701 (-2.3A)
 0.68A 3dtuB-3sbqA:
8.0		 3dtuB-3sbqA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 CYH A 618
CYH A 622
HIS A 626
 CUA  A 701 (-2.2A)
CUA  A 701 (-2.3A)
CUA  A 701 (-3.0A)
 0.25A 3dtuB-3sbqA:
8.0		 3dtuB-3sbqA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 CYH A 618
CYH A 622
HIS A 626
 CUA  A 701 (-2.2A)
CUA  A 701 (-2.3A)
CUA  A 701 (-3.0A)
 0.24A 3dtuD-3sbqA:
7.6		 3dtuD-3sbqA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD4_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 HIS A 583
CYH A 618
CYH A 622
MET A 629
 CUA  A 701 (-4.3A)
CUA  A 701 (-2.2A)
CUA  A 701 (-2.3A)
CUA  A 701 (-2.3A)
 0.73A 3dtuD-3sbqA:
7.6		 3dtuD-3sbqA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 ARG A 159
ASP A 511
ASP A 514
PRO A 515
 None
 0.70A 3fgrB-3sbqA:
undetectable		 3fgrB-3sbqA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_1
(REPRESSOR PROTEIN
MPHR(A))		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 5 ASN A 324
ASN A 241
HIS A 382
ALA A 340
 CA  A 703 (-3.0A)
CL  A 704 (-3.7A)
CUK  A 702 ( 3.3A)
None
 1.49A 3frqA-3sbqA:
undetectable		 3frqA-3sbqA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 LEU A 355
ARG A 367
SER A 331
GLY A 372
 None
 1.08A 3hcrB-3sbqA:
undetectable		 3hcrB-3sbqA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 SER A 332
ASN A 390
ILE A 476
GLY A 446
 None
 0.96A 3lslA-3sbqA:
undetectable
3lslD-3sbqA:
undetectable		 3lslA-3sbqA:
19.71
3lslD-3sbqA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 LYS A 164
SER A 602
GLN A 600
 None
 1.14A 3si7A-3sbqA:
undetectable		 3si7A-3sbqA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 HIS A 130
HIS A 178
HIS A 129
HIS A 326
 CUK  A 702 (-3.2A)
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
CUK  A 702 (-3.1A)
 0.94A 3w6hA-3sbqA:
undetectable		 3w6hA-3sbqA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		5 / 12 VAL A 155
ILE A 222
ILE A 497
GLU A 440
HIS A 178
 None
None
None
None
CUK  A 702 (-3.1A)
 1.19A 4a97B-3sbqA:
undetectable
4a97C-3sbqA:
undetectable		 4a97B-3sbqA:
19.40
4a97C-3sbqA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 5 GLU A 373
ARG A 367
PRO A 322
SER A 344
 None
 1.39A 4k17B-3sbqA:
undetectable		 4k17B-3sbqA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		5 / 12 PHE A 490
GLY A  77
ALA A 156
ARG A  95
ILE A 158
 None
 1.04A 4krhB-3sbqA:
undetectable		 4krhB-3sbqA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.87A 4p6sA-3sbqA:
undetectable		 4p6sA-3sbqA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.93A 4p6sB-3sbqA:
undetectable		 4p6sB-3sbqA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 6 ALA A 451
GLN A 472
LEU A 449
LEU A 425
 None
 1.14A 4xoyA-3sbqA:
2.3		 4xoyA-3sbqA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 6 ALA A 451
GLN A 472
LEU A 449
LEU A 425
 None
 1.22A 4xp3A-3sbqA:
undetectable		 4xp3A-3sbqA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 ALA A 193
HIS A 130
ASN A 148
THR A 242
 None
CUK  A 702 (-3.2A)
None
None
 1.20A 5db5A-3sbqA:
undetectable
5db5B-3sbqA:
undetectable		 5db5A-3sbqA:
21.34
5db5B-3sbqA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.88A 5i3aA-3sbqA:
undetectable		 5i3aA-3sbqA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.89A 5i3aB-3sbqA:
undetectable		 5i3aB-3sbqA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.86A 5i3bA-3sbqA:
undetectable		 5i3bA-3sbqA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.93A 5m8rA-3sbqA:
undetectable		 5m8rA-3sbqA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.94A 5m8rB-3sbqA:
undetectable		 5m8rB-3sbqA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.93A 5m8rC-3sbqA:
undetectable		 5m8rC-3sbqA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.92A 5m8rD-3sbqA:
undetectable		 5m8rD-3sbqA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 THR A 217
HIS A 201
ASN A 173
 None
 0.94A 5n4tA-3sbqA:
undetectable		 5n4tA-3sbqA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 ASP A 240
HIS A 178
HIS A 130
HIS A 326
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.2A)
CUK  A 702 (-3.1A)
 1.42A 5ncdD-3sbqA:
undetectable		 5ncdD-3sbqA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
ASP A 127
HIS A 129
 None
None
CUK  A 702 (-3.5A)
 0.69A 5oexA-3sbqA:
25.2		 5oexA-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 178
ASP A 240
HIS A 326
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.78A 5oexA-3sbqA:
25.2		 5oexA-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 326
ASP A 240
HIS A 178
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.76A 5oexA-3sbqA:
25.2		 5oexA-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 LYS A 150
HIS A 178
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
 0.96A 5oexA-3sbqA:
25.2		 5oexA-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA603_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 LYS A 150
HIS A 178
HIS A 130
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.2A)
CUK  A 702 (-3.5A)
 1.25A 5oexA-3sbqA:
25.2		 5oexA-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 433
HIS A 494
HIS A 129
 CUK  A 702 (-3.1A)
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.53A 5oexA-3sbqA:
25.2		 5oexA-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
ASP A 127
HIS A 129
 None
None
CUK  A 702 (-3.5A)
 0.64A 5oexB-3sbqA:
7.3		 5oexB-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 178
ASP A 240
HIS A 326
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.71A 5oexB-3sbqA:
7.3		 5oexB-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 LYS A 150
HIS A 178
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
 1.07A 5oexB-3sbqA:
7.3		 5oexB-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB603_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 LYS A 150
HIS A 178
HIS A 130
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.2A)
CUK  A 702 (-3.5A)
 1.28A 5oexB-3sbqA:
7.3		 5oexB-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
ASP A 127
HIS A 129
 None
None
CUK  A 702 (-3.5A)
 0.67A 5oexC-3sbqA:
8.9		 5oexC-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 178
ASP A 240
HIS A 326
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.67A 5oexC-3sbqA:
8.9		 5oexC-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 326
ASP A 240
HIS A 178
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.75A 5oexC-3sbqA:
8.9		 5oexC-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC602_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 LYS A 150
HIS A 178
HIS A 130
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.2A)
CUK  A 702 (-3.5A)
 1.28A 5oexC-3sbqA:
8.9		 5oexC-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 LYS A 150
HIS A 178
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
 1.04A 5oexC-3sbqA:
8.9		 5oexC-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
ASP A 127
HIS A 129
 None
None
CUK  A 702 (-3.5A)
 0.70A 5oexD-3sbqA:
7.2		 5oexD-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 178
ASP A 240
HIS A 326
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.68A 5oexD-3sbqA:
7.2		 5oexD-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 326
ASP A 240
HIS A 178
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.76A 5oexD-3sbqA:
7.2		 5oexD-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 LYS A 150
HIS A 178
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
 0.97A 5oexD-3sbqA:
7.2		 5oexD-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD604_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 LYS A 150
HIS A 178
HIS A 130
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.2A)
CUK  A 702 (-3.5A)
 1.23A 5oexD-3sbqA:
7.2		 5oexD-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 MET A 523
GLU A 567
ARG A 545
 None
 0.95A 5tjyA-3sbqA:
undetectable		 5tjyA-3sbqA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 MET A 523
GLU A 567
ARG A 545
 None
 0.92A 5tjzA-3sbqA:
undetectable		 5tjzA-3sbqA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.73A 5x1fA-3sbqA:
undetectable		 5x1fA-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.76A 5xdqA-3sbqA:
undetectable		 5xdqA-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.76A 5xdqN-3sbqA:
undetectable		 5xdqN-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 GLY A 631
VAL A 546
MET A 548
 None
 0.60A 5ycpA-3sbqA:
undetectable		 5ycpA-3sbqA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		5 / 11 HIS A 130
HIS A 178
HIS A 326
HIS A 382
HIS A 494
 CUK  A 702 (-3.2A)
CUK  A 702 (-3.1A)
CUK  A 702 (-3.1A)
CUK  A 702 ( 3.3A)
CUK  A 702 (-3.3A)
 1.14A 5z0mA-3sbqA:
undetectable
5z0mB-3sbqA:
undetectable		 5z0mA-3sbqA:
8.46
5z0mB-3sbqA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.73A 5z86A-3sbqA:
undetectable		 5z86A-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.77A 5z86N-3sbqA:
undetectable		 5z86N-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 5 VAL A 319
TRP A 274
PRO A 325
THR A 316
 None
 1.42A 6cduA-3sbqA:
undetectable
6cduB-3sbqA:
undetectable		 6cduA-3sbqA:
17.94
6cduB-3sbqA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 5 VAL A 319
TRP A 274
PRO A 325
THR A 316
 None
 1.50A 6cduI-3sbqA:
undetectable
6cduJ-3sbqA:
undetectable		 6cduI-3sbqA:
17.94
6cduJ-3sbqA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_C_GM4C301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		5 / 11 ALA A 436
TYR A 246
TYR A 140
ASP A 243
ALA A 444
 None
 1.34A 6dk1C-3sbqA:
undetectable		 6dk1C-3sbqA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.72A 6nmpA-3sbqA:
undetectable		 6nmpA-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.72A 6nmpN-3sbqA:
undetectable		 6nmpN-3sbqA:
21.05