SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sbu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		5 / 11 PHE A 152
ILE A 237
ASP A 129
LEU A 132
PHE A  64
 None
None
GOL  A 287 ( 3.9A)
GOL  A 289 ( 4.2A)
None
 1.34A 1ju6A-3sbuA:
undetectable		 1ju6A-3sbuA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		5 / 12 LEU A 116
ILE A  68
VAL A 137
TYR A 114
TYR A 239
 None
None
None
MLY  A 255 ( 4.0A)
GOL  A 289 (-4.8A)
 1.27A 2japA-3sbuA:
undetectable		 2japA-3sbuA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		5 / 12 LEU A 116
ILE A  68
VAL A 137
TYR A 114
TYR A 239
 None
None
None
MLY  A 255 ( 4.0A)
GOL  A 289 (-4.8A)
 1.26A 2japC-3sbuA:
undetectable		 2japC-3sbuA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		5 / 12 LEU A 116
ILE A  68
VAL A 137
TYR A 114
TYR A 239
 None
None
None
MLY  A 255 ( 4.0A)
GOL  A 289 (-4.8A)
 1.24A 2japD-3sbuA:
undetectable		 2japD-3sbuA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 258
GLY A 256
VAL A 137
PHE A 152
ILE A  68
 None
MLY  A 255 ( 2.4A)
None
None
None
 1.00A 3eluA-3sbuA:
undetectable		 3eluA-3sbuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		4 / 8 ASN A 236
THR A 115
LEU A 254
ASN A 243
 None
PEG  A 293 ( 4.4A)
MLY  A 255 ( 4.5A)
GOL  A 285 (-3.2A)
 1.10A 3kp2A-3sbuA:
undetectable
3kp2B-3sbuA:
undetectable		 3kp2A-3sbuA:
19.10
3kp2B-3sbuA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		4 / 8 PHE A 152
PHE A  64
PHE A  71
ALA A  72
 None
 0.85A 3t3sD-3sbuA:
undetectable		 3t3sD-3sbuA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		4 / 8 PHE A 267
PHE A 177
PHE A 184
ALA A 185
 None
 0.70A 3t3sD-3sbuA:
undetectable		 3t3sD-3sbuA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		4 / 7 PHE A 152
PHE A  64
PHE A  71
ALA A  72
 None
 0.79A 4ejgA-3sbuA:
undetectable		 4ejgA-3sbuA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		4 / 7 PHE A 267
PHE A 177
PHE A 184
ALA A 185
 None
 0.70A 4ejgA-3sbuA:
undetectable		 4ejgA-3sbuA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		5 / 8 PHE A 267
PHE A 177
PHE A 184
ALA A 185
LEU A 254
 None
None
None
None
MLY  A 255 ( 4.5A)
 0.79A 4ejgB-3sbuA:
undetectable		 4ejgB-3sbuA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		4 / 7 PHE A 267
PHE A 177
ALA A 185
LEU A 254
 None
None
None
MLY  A 255 ( 4.5A)
 0.79A 4ejgC-3sbuA:
undetectable		 4ejgC-3sbuA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		4 / 6 PHE A 267
PHE A 177
ALA A 185
LEU A 254
 None
None
None
MLY  A 255 ( 4.5A)
 0.76A 4ejgD-3sbuA:
undetectable		 4ejgD-3sbuA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		3 / 3 GLU A 138
LYS A 150
ASN A 238
 GOL  A 285 ( 4.3A)
MLY  A 149 ( 3.3A)
MLY  A 149 ( 4.2A)
 1.10A 4y1dA-3sbuA:
undetectable
4y1dD-3sbuA:
undetectable		 4y1dA-3sbuA:
18.11
4y1dD-3sbuA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		5 / 12 ASP A 176
GLU A 175
LEU A 254
LEU A 229
LEU A 265
 None
GOL  A 288 (-3.2A)
MLY  A 255 ( 4.5A)
None
None
 1.13A 5hnwB-3sbuA:
undetectable		 5hnwB-3sbuA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		5 / 12 ASP A 176
GLU A 175
LEU A 254
LEU A 229
LEU A 265
 None
GOL  A 288 (-3.2A)
MLY  A 255 ( 4.5A)
None
None
 1.11A 5hnyB-3sbuA:
undetectable		 5hnyB-3sbuA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		4 / 5 LEU A 199
PHE A 201
LEU A 276
PHE A 184
 None
None
MLY  A 278 ( 4.9A)
None
 1.25A 5iy5P-3sbuA:
undetectable
5iy5W-3sbuA:
undetectable		 5iy5P-3sbuA:
21.48
5iy5W-3sbuA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		3 / 3 ASP A 119
ASN A 246
PHE A 181
 None
 0.86A 5jglB-3sbuA:
undetectable		 5jglB-3sbuA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN
(Bacteroides
fragilis) 		5 / 12 SER A 112
SER A 283
THR A 282
PHE A 279
LEU A 229
 PEG  A 293 (-2.9A)
None
GOL  A 290 (-3.4A)
None
None
 1.24A 6a93A-3sbuA:
undetectable		 6a93A-3sbuA:
21.79