SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sbx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD4_B_CHDB926_0 (FERROCHELATASE)	3sbx	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium marinum)	5 / 10	LEU A 89 ILE A 72 ARG A 98 VAL A 51 GLY A 55	None None AMP A 188 (-3.1A) None None	1.40A	2qd4B-3sbxA: 3.1	2qd4B-3sbxA: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A25_A_SAMA279_1 (UNCHARACTERIZED PROTEIN PH0793)	3sbx	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium marinum)	3 / 3	MET A 133 GLU A 103 ASP A 120	None None AMP A 188 (-3.5A)	0.95A	3a25A-3sbxA: 3.6	3a25A-3sbxA: 22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L1W_B_STRB402_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	3sbx	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium marinum)	4 / 6	VAL A 174 VAL A 139 ILE A 110 LEU A 29	None	0.98A	4l1wB-3sbxA: undetectable	4l1wB-3sbxA: 22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C06_D_FI8D1404_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	3sbx	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium marinum)	3 / 3	ARG A 98 LYS A 99 ARG A 170	AMP A 188 (-3.1A) AMP A 188 (-2.6A) None	1.21A	6c06D-3sbxA: undetectable	6c06D-3sbxA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QD4_B_CHDB926_0","FERROCHELATASE","3sbx","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium marinum",5,"LEU A  89;ILE A  72;ARG A  98;VAL A  51;GLY A  55","None;None;AMP A 188 (-3.1A);None;None","1.40A","2qd4B-3sbxA:3.1","2qd4B-3sbxA:19.35"],["3A25_A_SAMA279_1","UNCHARACTERIZED PROTEIN PH0793","3sbx","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium marinum",3,"MET A 133;GLU A 103;ASP A 120","None;None;AMP A 188 (-3.5A)","0.95A","3a25A-3sbxA:3.6","3a25A-3sbxA:22.26"],["4L1W_B_STRB402_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","3sbx","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium marinum",4,"VAL A 174;VAL A 139;ILE A 110;LEU A  29","None","0.98A","4l1wB-3sbxA:undetectable","4l1wB-3sbxA:22.43"],["6C06_D_FI8D1404_1","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","3sbx","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium marinum",3,"ARG A  98;LYS A  99;ARG A 170","AMP A 188 (-3.1A);AMP A 188 (-2.6A);None","1.21A","6c06D-3sbxA:undetectable","6c06D-3sbxA:undetectable"]]