SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sci'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_B_CLMB221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3sci	SPIKE GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	5 / 12	PHE E 329 SER E 353 VAL E 369 PHE E 501 PHE E 364	None	1.07A	3u9fB-3sciE: undetectable 3u9fC-3sciE: undetectable	3u9fB-3sciE: 20.95 3u9fC-3sciE: 20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_F_CLMF221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3sci	SPIKE GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	5 / 10	PHE E 364 PHE E 329 SER E 353 VAL E 369 PHE E 501	None	1.17A	3u9fD-3sciE: 0.0 3u9fF-3sciE: 0.0	3u9fD-3sciE: 20.95 3u9fF-3sciE: 20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_O_CLMO221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3sci	SPIKE GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	5 / 11	PHE E 364 PHE E 329 SER E 353 VAL E 369 PHE E 501	None	1.08A	3u9fM-3sciE: undetectable 3u9fO-3sciE: undetectable	3u9fM-3sciE: 20.95 3u9fO-3sciE: 20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X24_A_LSNA502_1 (CYTOCHROME P450 2C9)	3sci	SPIKE GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	5 / 12	VAL E 496 VAL E 394 ASP E 393 GLY E 391 THR E 487	None	1.24A	5x24A-3sciE: undetectable	5x24A-3sciE: 17.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3U9F_B_CLMB221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","3sci","SPIKE GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",5,"PHE E 329;SER E 353;VAL E 369;PHE E 501;PHE E 364","None","1.07A","3u9fB-3sciE:undetectable;3u9fC-3sciE:undetectable","3u9fB-3sciE:20.95;3u9fC-3sciE:20.95"],["3U9F_F_CLMF221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","3sci","SPIKE GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",5,"PHE E 364;PHE E 329;SER E 353;VAL E 369;PHE E 501","None","1.17A","3u9fD-3sciE:0.0;3u9fF-3sciE:0.0","3u9fD-3sciE:20.95;3u9fF-3sciE:20.95"],["3U9F_O_CLMO221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","3sci","SPIKE GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",5,"PHE E 364;PHE E 329;SER E 353;VAL E 369;PHE E 501","None","1.08A","3u9fM-3sciE:undetectable;3u9fO-3sciE:undetectable","3u9fM-3sciE:20.95;3u9fO-3sciE:20.95"],["5X24_A_LSNA502_1","CYTOCHROME P450 2C9","3sci","SPIKE GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",5,"VAL E 496;VAL E 394;ASP E 393;GLY E 391;THR E 487","None","1.24A","5x24A-3sciE:undetectable","5x24A-3sciE:17.86"]]