SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sdo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 4 LEU A 392
PRO A 271
LEU A 394
ARG A  41
 None
 1.39A 1hrkB-3sdoA:
undetectable		 1hrkB-3sdoA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		3 / 3 ASN A  18
PHE A 399
VAL A 287
 None
 0.72A 1kijA-3sdoA:
undetectable		 1kijA-3sdoA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		5 / 11 GLU A 279
GLY A 274
ARG A  41
LEU A 401
HIS A 407
 None
 1.35A 1mjqA-3sdoA:
0.7
1mjqB-3sdoA:
undetectable		 1mjqA-3sdoA:
15.66
1mjqB-3sdoA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		5 / 12 ALA A 225
ILE A 222
SER A 217
ALA A 252
ILE A 212
 None
 1.17A 1ve3A-3sdoA:
undetectable		 1ve3A-3sdoA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		5 / 12 ALA A 225
ILE A 222
SER A 217
ALA A 252
ILE A 212
 None
 1.15A 1ve3B-3sdoA:
undetectable		 1ve3B-3sdoA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 7 ASN A 201
TYR A 103
ASN A 104
VAL A 196
 None
 1.27A 1wu8A-3sdoA:
undetectable
1wu8C-3sdoA:
undetectable		 1wu8A-3sdoA:
20.50
1wu8C-3sdoA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 5 LEU A 300
ILE A 336
LEU A 339
ARG A 343
 None
 0.91A 2byoA-3sdoA:
undetectable		 2byoA-3sdoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 4 LEU A 392
PRO A 271
LEU A 394
ARG A  41
 None
 1.40A 2hrcB-3sdoA:
undetectable		 2hrcB-3sdoA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 7 ARG A  72
ILE A  55
PHE A  54
GLN A  13
 None
 1.06A 2jc9A-3sdoA:
undetectable		 2jc9A-3sdoA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 4 LEU A 392
PRO A 271
LEU A 394
ARG A  41
 None
 1.44A 2pnjB-3sdoA:
undetectable		 2pnjB-3sdoA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 396
ALA A  21
PRO A 271
THR A 363
 None
 1.00A 2q6oA-3sdoA:
undetectable		 2q6oA-3sdoA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 8 ILE A 212
TRP A 161
TRP A 122
PHE A 109
 None
 1.48A 3ccfB-3sdoA:
undetectable		 3ccfB-3sdoA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 7 GLY A 369
GLY A 274
GLU A 365
ALA A 373
 None
 0.79A 3fpjB-3sdoA:
undetectable		 3fpjB-3sdoA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 4 LEU A 392
PRO A 271
LEU A 394
ARG A  44
 None
 1.44A 3hcoA-3sdoA:
undetectable		 3hcoA-3sdoA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		3 / 3 GLY A 268
PRO A 271
LEU A 392
 None
 0.57A 3hcpB-3sdoA:
undetectable		 3hcpB-3sdoA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		5 / 12 ALA A  42
LEU A  79
LEU A  82
GLY A  93
ILE A  12
 None
 1.32A 3lbdA-3sdoA:
undetectable		 3lbdA-3sdoA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 6 LEU A 324
PRO A 319
LEU A 297
LEU A 300
 None
 1.08A 3q1eA-3sdoA:
undetectable
3q1eC-3sdoA:
undetectable		 3q1eA-3sdoA:
13.68
3q1eC-3sdoA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		3 / 3 PHE A 390
TYR A 246
LEU A  11
 None
 0.74A 3sueB-3sdoA:
undetectable		 3sueB-3sdoA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 6 LEU A 427
ALA A  42
THR A  86
LEU A  79
 None
 0.94A 3t3zA-3sdoA:
undetectable		 3t3zA-3sdoA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 6 LEU A 427
ALA A  42
THR A  86
LEU A  79
 None
 0.93A 3t3zB-3sdoA:
undetectable		 3t3zB-3sdoA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 6 LEU A 427
ALA A  42
THR A  86
LEU A  79
 None
 0.91A 3t3zD-3sdoA:
undetectable		 3t3zD-3sdoA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_2
(NEURAMINIDASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 5 LEU A 169
ASP A 166
ARG A 204
ARG A 203
 None
 1.36A 4cpzA-3sdoA:
undetectable		 4cpzA-3sdoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		3 / 3 TYR A 284
THR A 356
GLU A 365
 None
 0.76A 4df3A-3sdoA:
undetectable		 4df3A-3sdoA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		3 / 3 TYR A 284
THR A 356
GLU A 365
 None
 0.78A 4df3B-3sdoA:
undetectable		 4df3B-3sdoA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		6 / 12 VAL A 382
ALA A 386
PHE A 367
SER A 376
LEU A 412
VAL A 411
 None
None
None
None
None
EDO  A 451 ( 4.1A)
 1.48A 4eckA-3sdoA:
undetectable		 4eckA-3sdoA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 5 PHE A  54
PHE A  52
LEU A 394
PRO A 271
 None
 1.37A 4o8zA-3sdoA:
undetectable		 4o8zA-3sdoA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		5 / 9 PRO A 271
LEU A 401
GLY A 400
MET A 378
VAL A 405
 None
 1.44A 4x3mA-3sdoA:
3.8		 4x3mA-3sdoA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 7 GLY A 159
ASP A 165
TRP A 164
TYR A 440
 None
 0.94A 6ag0A-3sdoA:
8.9		 6ag0A-3sdoA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC609_0
(ALPHA-AMYLASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 7 GLY A 159
ASP A 165
TRP A 164
TYR A 440
 None
 0.96A 6ag0C-3sdoA:
8.9		 6ag0C-3sdoA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		5 / 12 VAL A 105
TYR A 440
LEU A 187
VAL A 196
LEU A 200
 None
 1.20A 6ajiA-3sdoA:
undetectable		 6ajiA-3sdoA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		3 / 3 ALA A 151
PHE A 193
GLN A 145
 None
 0.83A 6eceA-3sdoA:
undetectable		 6eceA-3sdoA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		3 / 3 PHE A 367
ARG A 380
ALA A 242
 None
 0.92A 6ecfB-3sdoA:
undetectable		 6ecfB-3sdoA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		5 / 11 ILE A  12
LEU A  11
MET A 391
LEU A  91
PHE A  52
 None
 1.26A 6hupA-3sdoA:
undetectable
6hupB-3sdoA:
undetectable		 6hupA-3sdoA:
10.60
6hupB-3sdoA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 5 GLY A 133
THR A 132
SER A  97
SER A  96
 None
 0.92A 6jmjA-3sdoA:
undetectable		 6jmjA-3sdoA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 7 GLY A 133
THR A 132
SER A  97
SER A  96
 None
 0.95A 6jnhA-3sdoA:
undetectable		 6jnhA-3sdoA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3sdo NITRILOTRIACETATE
MONOOXYGENASE
(Burkholderia
pseudomallei) 		4 / 6 GLY A 133
THR A 132
SER A  97
SER A  96
 None
 0.95A 6jogA-3sdoA:
undetectable		 6jogA-3sdoA:
17.26