SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3se4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 3se4 INTERFERON OMEGA-1
(Homo
sapiens) 		5 / 10 ILE B 150
PHE B  40
MET B  44
VAL B  58
LEU B 122
 None
 1.37A 2w98A-3se4B:
undetectable		 2w98A-3se4B:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3se4 INTERFERON OMEGA-1
(Homo
sapiens) 		4 / 8 ILE B 150
TYR B 125
LEU B 122
PHE B  40
 None
 1.01A 3rqwI-3se4B:
undetectable
3rqwJ-3se4B:
undetectable		 3rqwI-3se4B:
19.69
3rqwJ-3se4B:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3se4 INTERFERON OMEGA-1
(Homo
sapiens) 		3 / 3 SER B 139
GLU B 135
ASP B  34
 None
 0.85A 4xudA-3se4B:
undetectable		 4xudA-3se4B:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3se4 INTERFERON OMEGA-1
(Homo
sapiens) 		3 / 3 VAL B  58
LEU B  20
MET B 151
 None
 0.88A 5ikrA-3se4B:
undetectable		 5ikrA-3se4B:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3se4 INTERFERON OMEGA-1
(Homo
sapiens) 		3 / 3 THR B  72
SER B  75
ASP B  85
 None
 0.86A 5kvaB-3se4B:
undetectable		 5kvaB-3se4B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 3se4 INTERFERON OMEGA-1
(Homo
sapiens) 		5 / 12 SER B 153
TYR B 125
PHE B 126
ILE B 129
LEU B  69
 None
 1.20A 5zwrB-3se4B:
undetectable		 5zwrB-3se4B:
17.40