SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3se5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 3se5 CELL FILAMENTATION
PROTEIN FIC-RELATED
PROTEIN
(Neisseria
meningitidis) 		4 / 7 GLU A  86
GLY A  41
PHE A 109
ILE A  60
 None
 0.91A 2qmzA-3se5A:
undetectable
2qmzB-3se5A:
undetectable		 2qmzA-3se5A:
18.61
2qmzB-3se5A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3se5 CELL FILAMENTATION
PROTEIN FIC-RELATED
PROTEIN
(Neisseria
meningitidis) 		3 / 3 GLY A  58
PRO A 108
LEU A  42
 None
 0.54A 3hcpB-3se5A:
undetectable		 3hcpB-3se5A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 3se5 CELL FILAMENTATION
PROTEIN FIC-RELATED
PROTEIN
(Neisseria
meningitidis) 		3 / 3 TYR A 143
TYR A 100
GLU A 148
 ANP  A 201 (-4.7A)
None
ANP  A 201 (-4.9A)
 0.90A 3pfgA-3se5A:
undetectable		 3pfgA-3se5A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 3se5 CELL FILAMENTATION
PROTEIN FIC-RELATED
PROTEIN
(Neisseria
meningitidis) 		4 / 8 ALA A  40
GLY A  41
THR A  38
GLN A  44
 None
None
None
P6G  A 202 ( 3.5A)
 0.90A 3rglA-3se5A:
undetectable		 3rglA-3se5A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3se5 CELL FILAMENTATION
PROTEIN FIC-RELATED
PROTEIN
(Neisseria
meningitidis) 		3 / 3 LYS A 127
GLU A  90
TRP A 120
 None
 1.09A 3v4tH-3se5A:
undetectable		 3v4tH-3se5A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3se5 CELL FILAMENTATION
PROTEIN FIC-RELATED
PROTEIN
(Neisseria
meningitidis) 		4 / 5 ALA A  75
ILE A  65
LEU A 110
ASN A  64
 None
 1.13A 4g19A-3se5A:
undetectable		 4g19A-3se5A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3se5 CELL FILAMENTATION
PROTEIN FIC-RELATED
PROTEIN
(Neisseria
meningitidis) 		5 / 11 PHE A  26
SER A  28
GLY A  29
ILE A  97
LEU A 157
 None
 1.09A 4kt0A-3se5A:
undetectable
4kt0J-3se5A:
undetectable		 4kt0A-3se5A:
11.33
4kt0J-3se5A:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 3se5 CELL FILAMENTATION
PROTEIN FIC-RELATED
PROTEIN
(Neisseria
meningitidis) 		4 / 6 LEU A  82
LEU A  42
MET A  88
VAL A 124
 None
 1.07A 4okbA-3se5A:
undetectable		 4okbA-3se5A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 3se5 CELL FILAMENTATION
PROTEIN FIC-RELATED
PROTEIN
(Neisseria
meningitidis) 		3 / 3 PHE A  93
THR A 117
LEU A 157
 None
 0.68A 4qztA-3se5A:
undetectable		 4qztA-3se5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3se5 CELL FILAMENTATION
PROTEIN FIC-RELATED
PROTEIN
(Neisseria
meningitidis) 		4 / 4 GLN A 145
THR A 141
LEU A 161
LEU A 160
 None
 1.27A 5m5kB-3se5A:
undetectable		 5m5kB-3se5A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3se5 CELL FILAMENTATION
PROTEIN FIC-RELATED
PROTEIN
(Neisseria
meningitidis) 		4 / 8 ILE A  60
GLN A  43
ARG A  47
SER A 116
 None
 1.12A 6c06C-3se5A:
undetectable		 6c06C-3se5A:
undetectable