SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3see'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 3see HYPOTHETICAL SUGAR
BINDING PROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A  47
ALA A  61
VAL A  32
 None
 0.91A 1c4dC-3seeA:
undetectable
1c4dD-3seeA:
undetectable		 1c4dC-3seeA:
5.05
1c4dD-3seeA:
5.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 3see HYPOTHETICAL SUGAR
BINDING PROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 PHE A 141
LEU A 195
SER A 156
 None
 0.51A 1e7aA-3seeA:
undetectable		 1e7aA-3seeA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 3see HYPOTHETICAL SUGAR
BINDING PROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 ALA A  61
VAL A  32
TRP A  47
 None
 0.92A 1tkqB-3seeA:
undetectable		 1tkqB-3seeA:
4.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 3see HYPOTHETICAL SUGAR
BINDING PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 9 ILE A 214
PHE A  28
ALA A  73
GLU A 224
 None
 0.86A 2vufA-3seeA:
undetectable		 2vufA-3seeA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 3see HYPOTHETICAL SUGAR
BINDING PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 225
VAL A 212
VAL A 122
VAL A 175
VAL A 173
 None
 1.24A 3iw1A-3seeA:
undetectable		 3iw1A-3seeA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3see HYPOTHETICAL SUGAR
BINDING PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 ILE A 214
GLY A 216
ILE A 225
LEU A 215
 None
 0.86A 5dzkl-3seeA:
undetectable
5dzkz-3seeA:
undetectable		 5dzkl-3seeA:
20.43
5dzkz-3seeA:
1.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3see HYPOTHETICAL SUGAR
BINDING PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 107
ILE A 164
LYS A 172
VAL A 173
 None
 1.14A 5jh7C-3seeA:
undetectable		 5jh7C-3seeA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3see HYPOTHETICAL SUGAR
BINDING PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 9 ASP A 209
ASN A 128
SER A  40
PHE A  48
GLY A  45
 None
 1.23A 6awpA-3seeA:
undetectable		 6awpA-3seeA:
16.85