SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sei'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 3sei CASKIN-1
(Homo
sapiens) 		5 / 10 LEU A  21
ASN A  25
VAL A  49
GLY A  48
LEU A  19
 None
 1.12A 1fkoA-3seiA:
undetectable		 1fkoA-3seiA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 3sei CASKIN-1
(Homo
sapiens) 		5 / 11 LEU A  21
ASN A  25
VAL A  49
GLY A  48
LEU A  19
 None
 1.12A 1fkpA-3seiA:
undetectable		 1fkpA-3seiA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 3sei CASKIN-1
(Homo
sapiens) 		4 / 8 PHE A  26
LEU A  14
TRP A  13
TYR A  22
 None
 0.97A 1rmtD-3seiA:
undetectable		 1rmtD-3seiA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 3sei CASKIN-1
(Homo
sapiens) 		3 / 3 LEU A  19
HIS A  54
LYS A  57
 None
 1.13A 1y7iA-3seiA:
undetectable		 1y7iA-3seiA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 3sei CASKIN-1
(Homo
sapiens) 		5 / 12 ILE A  47
VAL A  10
TRP A  13
LEU A  14
PHE A  17
 None
 1.23A 2jj8C-3seiA:
undetectable		 2jj8C-3seiA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3sei CASKIN-1
(Homo
sapiens) 		5 / 10 LEU A  21
ASN A  25
VAL A  49
GLY A  48
LEU A  19
 None
 1.23A 3lp1A-3seiA:
undetectable		 3lp1A-3seiA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 3sei CASKIN-1
(Homo
sapiens) 		5 / 12 LEU A  21
ASN A  25
VAL A  49
GLY A  48
LEU A  19
 None
 1.30A 3medA-3seiA:
undetectable
3medB-3seiA:
undetectable		 3medA-3seiA:
14.37
3medB-3seiA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 3sei CASKIN-1
(Homo
sapiens) 		3 / 3 ASP A  32
LEU A  88
GLY A  87
 None
 0.53A 4xmfA-3seiA:
undetectable		 4xmfA-3seiA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3sei CASKIN-1
(Homo
sapiens) 		5 / 12 LEU A  95
LEU A 114
ILE A  86
LEU A  79
LEU A 135
 None
 0.93A 5og9B-3seiA:
undetectable		 5og9B-3seiA:
15.86