SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sen'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FKP_A_NVPA999_1 (HIV-1 RT, A-CHAIN)	3sen	CASKIN-1 (Homo sapiens)	5 / 11	LEU A 24 ASN A 28 VAL A 52 GLY A 51 LEU A 22	None	1.10A	1fkpA-3senA: undetectable	1fkpA-3senA: 15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LP1_A_NVPA701_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	3sen	CASKIN-1 (Homo sapiens)	5 / 10	LEU A 24 ASN A 28 VAL A 52 GLY A 51 LEU A 22	None	1.22A	3lp1A-3senA: undetectable	3lp1A-3senA: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MED_A_65BA561_0 (P51 REVERSE TRANSCRIPTASE P66 REVERSE TRANSCRIPTASE)	3sen	CASKIN-1 (Homo sapiens)	5 / 12	LEU A 24 ASN A 28 VAL A 52 GLY A 51 LEU A 22	None	1.30A	3medA-3senA: undetectable 3medB-3senA: undetectable	3medA-3senA: 14.52 3medB-3senA: 17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XMF_A_HSMA202_1 (NITROPHORIN-7)	3sen	CASKIN-1 (Homo sapiens)	3 / 3	ASP A 35 LEU A 91 GLY A 90	None	0.54A	4xmfA-3senA: undetectable	4xmfA-3senA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OG9_B_TESB502_1 (-)	3sen	CASKIN-1 (Homo sapiens)	5 / 12	LEU A 98 LEU A 117 ILE A 89 LEU A 82 LEU A 138	None	0.97A	5og9B-3senA: undetectable	5og9B-3senA: 17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_Q_PCFQ202_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 1)	3sen	CASKIN-1 (Homo sapiens)	4 / 6	ILE A 112 ALA A 134 ARG A 136 ASP A 46	None	1.10A	6hu9m-3senA: undetectable 6hu9q-3senA: undetectable	6hu9m-3senA: 13.52 6hu9q-3senA: 20.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FKP_A_NVPA999_1","HIV-1 RT, A-CHAIN","3sen","CASKIN-1","Homo sapiens",5,"LEU A  24;ASN A  28;VAL A  52;GLY A  51;LEU A  22","None","1.10A","1fkpA-3senA:undetectable","1fkpA-3senA:15.02"],["3LP1_A_NVPA701_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","3sen","CASKIN-1","Homo sapiens",5,"LEU A  24;ASN A  28;VAL A  52;GLY A  51;LEU A  22","None","1.22A","3lp1A-3senA:undetectable","3lp1A-3senA:14.06"],["3MED_A_65BA561_0","P51 REVERSE TRANSCRIPTASE;P66 REVERSE TRANSCRIPTASE","3sen","CASKIN-1","Homo sapiens",5,"LEU A  24;ASN A  28;VAL A  52;GLY A  51;LEU A  22","None","1.30A","3medA-3senA:undetectable;3medB-3senA:undetectable","3medA-3senA:14.52;3medB-3senA:17.96"],["4XMF_A_HSMA202_1","NITROPHORIN-7","3sen","CASKIN-1","Homo sapiens",3,"ASP A  35;LEU A  91;GLY A  90","None","0.54A","4xmfA-3senA:undetectable","4xmfA-3senA:21.69"],["5OG9_B_TESB502_1","-","3sen","CASKIN-1","Homo sapiens",5,"LEU A  98;LEU A 117;ILE A  89;LEU A  82;LEU A 138","None","0.97A","5og9B-3senA:undetectable","5og9B-3senA:17.12"],["6HU9_Q_PCFQ202_0","CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL;CYTOCHROME C OXIDASE SUBUNIT 1","3sen","CASKIN-1","Homo sapiens",4,"ILE A 112;ALA A 134;ARG A 136;ASP A  46","None","1.10A","6hu9m-3senA:undetectable;6hu9q-3senA:undetectable","6hu9m-3senA:13.52;6hu9q-3senA:20.57"]]