SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sf5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_A_DESA129_1
(TRANSTHYRETIN)		 3sf5 UREASE ACCESSORY
PROTEIN UREF
(Helicobacter
pylori) 		4 / 4 LYS A 221
LEU A 225
LEU A  87
SER A  88
 None
 1.33A 1tt6A-3sf5A:
undetectable		 1tt6A-3sf5A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3sf5 UREASE ACCESSORY
PROTEIN UREF
(Helicobacter
pylori) 		5 / 12 ILE A 191
PHE A 131
TYR A 150
ALA A 168
LEU A  89
 None
 1.38A 2x2nD-3sf5A:
undetectable		 2x2nD-3sf5A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3sf5 UREASE ACCESSORY
PROTEIN UREF
(Helicobacter
pylori) 		5 / 12 PHE A 146
ILE A 132
LEU A 135
LEU A 170
MET A 143
 None
 1.45A 3vn2A-3sf5A:
undetectable		 3vn2A-3sf5A:
26.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 3sf5 UREASE ACCESSORY
PROTEIN UREF
(Helicobacter
pylori) 		4 / 5 LEU A 170
ILE A 172
ASN A  39
VAL A  38
 None
None
PEG  A 258 (-3.7A)
PEG  A 258 (-4.6A)
 0.92A 4a9kB-3sf5A:
undetectable		 4a9kB-3sf5A:
18.52