SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sft'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		5 / 12 VAL A 214
ILE A 188
VAL A 281
SER A 172
LEU A 206
 None
 1.21A 1fm4A-3sftA:
undetectable		 1fm4A-3sftA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		6 / 12 ILE A 188
VAL A 228
PHE A 184
LEU A 212
VAL A 214
THR A 209
 None
 1.40A 2aw1A-3sftA:
undetectable		 2aw1A-3sftA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		3 / 3 ASP A 251
ASP A 268
ASP A 254
 None
 0.79A 2igtB-3sftA:
3.3		 2igtB-3sftA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		5 / 12 ILE A 279
LEU A 283
ILE A 177
ASN A 179
LEU A 180
 None
 1.01A 2w3bB-3sftA:
undetectable		 2w3bB-3sftA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		5 / 12 ILE A 279
LEU A 283
ILE A 177
ASN A 179
LEU A 180
 None
 1.05A 2w3mA-3sftA:
undetectable		 2w3mA-3sftA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		5 / 12 GLY A 220
GLU A 221
GLY A 238
ASP A 268
PHE A 265
 None
 1.33A 3qowA-3sftA:
undetectable		 3qowA-3sftA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		4 / 4 LEU A 180
PRO A 181
LEU A 212
ILE A 188
 None
 0.93A 4f4dB-3sftA:
3.1		 4f4dB-3sftA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFJ_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		5 / 12 ILE A 279
LEU A 283
ILE A 177
LEU A 180
VAL A 161
 None
 1.05A 4kfjB-3sftA:
undetectable		 4kfjB-3sftA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		4 / 5 LEU A 180
PRO A 181
LEU A 212
ILE A 188
 None
 0.93A 4klrA-3sftA:
2.5		 4klrA-3sftA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_C_PACC601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		5 / 12 SER A 210
PRO A 178
ILE A 176
VAL A 214
VAL A 228
 None
 1.39A 4yfbC-3sftA:
undetectable		 4yfbC-3sftA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_F_PACF601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		5 / 12 SER A 210
PRO A 178
ILE A 176
VAL A 214
VAL A 228
 None
 1.40A 4yfbF-3sftA:
undetectable		 4yfbF-3sftA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_I_PACI601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		5 / 12 SER A 210
PRO A 178
ILE A 176
VAL A 214
VAL A 228
 None
 1.39A 4yfbI-3sftA:
undetectable		 4yfbI-3sftA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_L_PACL601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		5 / 12 SER A 210
PRO A 178
ILE A 176
VAL A 214
VAL A 228
 None
 1.39A 4yfbL-3sftA:
undetectable		 4yfbL-3sftA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_C_ACTC1403_0
(L-THREONINE
3-DEHYDROGENASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		4 / 4 MET A 317
SER A 320
VAL A 321
GLY A 290
 None
 1.18A 5k50C-3sftA:
3.7		 5k50C-3sftA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		5 / 12 GLY A 290
VAL A 321
THR A 303
GLY A 302
GLY A 301
 None
 0.96A 6brdB-3sftA:
undetectable		 6brdB-3sftA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		4 / 4 ASP A 308
ILE A 336
PRO A 337
LEU A 331
 None
 1.36A 6mkeB-3sftA:
undetectable		 6mkeB-3sftA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3sft CHEMOTAXIS RESPONSE
REGULATOR
PROTEIN-GLUTAMATE
METHYLESTERASE
(Thermotoga
maritima) 		4 / 4 ASP A 308
ILE A 336
PRO A 337
LEU A 331
 None
 1.35A 6mkeA-3sftA:
undetectable		 6mkeA-3sftA:
17.51