SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sg1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DG5_A_TOPA201_1
(DIHYDROFOLATE
REDUCTASE)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		5 / 11 ILE A 217
ALA A 197
ILE A 193
LEU A 160
PRO A 163
 None
 1.07A 1dg5A-3sg1A:
undetectable		 1dg5A-3sg1A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		5 / 12 MET A 271
SER A 263
ILE A 264
ILE A 295
MET A 298
 None
 1.45A 1osvB-3sg1A:
undetectable		 1osvB-3sg1A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 7 MET A  92
GLN A  97
ASN A  23
GLU A 169
 None
 1.28A 1t9wA-3sg1A:
undetectable		 1t9wA-3sg1A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 7 TYR A 400
PHE A 403
ALA A 243
LEU A 410
 None
 1.18A 2vcvA-3sg1A:
undetectable		 2vcvA-3sg1A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 7 ILE A  28
ILE A  29
VAL A  72
LEU A  42
 None
 0.61A 3r9vA-3sg1A:
undetectable
3r9vB-3sg1A:
undetectable		 3r9vA-3sg1A:
20.92
3r9vB-3sg1A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		5 / 12 VAL A  72
GLY A 204
ALA A 202
ALA A 197
ASP A 195
 None
 0.98A 3sudD-3sg1A:
undetectable		 3sudD-3sg1A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 7 ASN A 255
PRO A 232
ARG A 234
ALA A 237
 None
 1.04A 3twpA-3sg1A:
undetectable		 3twpA-3sg1A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 7 ASN A 255
PRO A 232
ARG A 234
ALA A 237
 None
 0.96A 3twpB-3sg1A:
undetectable		 3twpB-3sg1A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 7 ASN A 255
PRO A 232
ARG A 234
ALA A 237
 None
 1.11A 3twpC-3sg1A:
undetectable		 3twpC-3sg1A:
22.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 7 ARG A  93
ALA A  94
HIS A 127
GLY A 166
 None
 0.44A 3v4tH-3sg1A:
61.8		 3v4tH-3sg1A:
50.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1507_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		3 / 3 ARG A 372
LYS A  22
ARG A 398
 None
 1.42A 3w1wA-3sg1A:
undetectable
3w1wB-3sg1A:
undetectable		 3w1wA-3sg1A:
21.23
3w1wB-3sg1A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		3 / 3 ARG A 398
ARG A 372
LYS A  22
 None
 1.38A 3w1wA-3sg1A:
undetectable
3w1wB-3sg1A:
undetectable		 3w1wA-3sg1A:
21.23
3w1wB-3sg1A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		5 / 12 PHE A 403
GLY A 381
ILE A   4
VAL A   6
ALA A 313
 None
 1.00A 4a6dA-3sg1A:
undetectable		 4a6dA-3sg1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		5 / 12 PHE A 403
GLY A 381
ILE A   4
VAL A   6
ALA A 313
 None
 1.03A 4a6eA-3sg1A:
undetectable		 4a6eA-3sg1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		5 / 12 SER A 322
ASN A 356
ASP A 345
ILE A 346
VAL A 336
 None
 1.04A 4dx5B-3sg1A:
undetectable		 4dx5B-3sg1A:
18.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E7C_C_ACTC506_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 5 ARG A  93
ILE A 124
HIS A 127
GLY A 166
 None
 1.32A 4e7cC-3sg1A:
55.7		 4e7cC-3sg1A:
50.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 6 ALA A 243
ILE A 235
ILE A 251
VAL A  18
 None
 0.82A 4r21A-3sg1A:
undetectable		 4r21A-3sg1A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		5 / 12 SER A 322
ASN A 356
ASP A 345
ILE A 346
VAL A 336
 None
 1.06A 4u8yB-3sg1A:
undetectable		 4u8yB-3sg1A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		5 / 12 SER A 322
ASN A 356
ASP A 345
ILE A 346
VAL A 336
 None
 1.06A 4u95B-3sg1A:
undetectable		 4u95B-3sg1A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 8 HIS A 335
GLN A 308
LEU A 377
THR A 239
 None
 1.04A 5hs6A-3sg1A:
undetectable		 5hs6A-3sg1A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		5 / 12 ILE A 251
GLY A  14
ASN A  13
ILE A 414
PHE A 403
 None
 1.23A 5igyA-3sg1A:
undetectable		 5igyA-3sg1A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 4 LEU A 196
MET A 203
ILE A 231
LEU A  42
 None
 1.36A 5nfpA-3sg1A:
undetectable		 5nfpA-3sg1A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		5 / 12 VAL A  96
LEU A 160
HIS A 127
PRO A  27
LEU A 196
 None
 1.41A 5syfB-3sg1A:
undetectable		 5syfB-3sg1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 6 ALA A  94
PRO A 114
VAL A  89
ASP A  50
 None
 0.92A 5umd2-3sg1A:
undetectable
5umdF-3sg1A:
undetectable		 5umd2-3sg1A:
10.94
5umdF-3sg1A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		5 / 12 LEU A 379
LEU A  12
ALA A 243
ILE A 414
ALA A 412
 None
 1.17A 5xiwD-3sg1A:
undetectable		 5xiwD-3sg1A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 6 ILE A 354
MET A 355
ASN A 356
ASP A 345
 None
 0.89A 6dhbA-3sg1A:
undetectable		 6dhbA-3sg1A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
anthracis) 		4 / 6 LEU A 396
ALA A 375
LEU A  48
ASN A  23
 None
 0.92A 6f88B-3sg1A:
undetectable		 6f88B-3sg1A:
10.99