SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sgg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A  56
ARG A  65
ILE A  49
 GOL  A 562 ( 4.5A)
None
None
 0.88A 1a4gB-3sggA:
undetectable		 1a4gB-3sggA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ILE A 231
ALA A 292
LEU A 227
LEU A 287
ILE A 335
HIS A  61
 None
 1.38A 1bsxA-3sggA:
undetectable		 1bsxA-3sggA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ILE A 231
ALA A 292
LEU A 227
LEU A 287
ILE A 335
HIS A  61
 None
 1.38A 1bsxB-3sggA:
undetectable		 1bsxB-3sggA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 427
SER A 330
ASN A 334
 None
 0.80A 1bx4A-3sggA:
undetectable		 1bx4A-3sggA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 174
ALA A 163
VAL A 101
ILE A 103
LEU A 130
 None
 1.03A 1fm6U-3sggA:
undetectable		 1fm6U-3sggA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A 374
HIS A 351
MET A 346
 None
 1.13A 1l5qB-3sggA:
2.3		 1l5qB-3sggA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 513
GLU A 474
ASP A 433
 None
 0.69A 1nt2A-3sggA:
undetectable		 1nt2A-3sggA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_A_CHCA202_1
(BILE ACID RECEPTOR)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 MET A  60
SER A 419
ILE A 360
TYR A 384
TYR A 376
 None
 1.47A 1osvA-3sggA:
0.0		 1osvA-3sggA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 427
TYR A 455
GLY A 332
GLY A 388
TYR A 394
 None
None
None
None
GOL  A 558 (-4.4A)
 1.08A 1p91A-3sggA:
undetectable		 1p91A-3sggA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLN A 429
PHE A 396
ASN A 434
GLU A 457
 None
 1.38A 1t9wA-3sggA:
undetectable		 1t9wA-3sggA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 TYR A 137
LEU A 133
LEU A 130
THR A 297
ILE A 173
 None
 1.06A 1tw4B-3sggA:
undetectable		 1tw4B-3sggA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ILE A 426
ILE A 431
ASN A 277
VAL A 276
 None
 0.71A 2nniA-3sggA:
undetectable		 2nniA-3sggA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ILE A 147
GLY A 172
ARG A 171
LEU A  92
 None
 0.74A 2vctA-3sggA:
undetectable		 2vctA-3sggA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ILE A 147
GLY A 172
ARG A 171
LEU A  92
 None
 0.73A 2vctB-3sggA:
undetectable		 2vctB-3sggA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ILE A 147
GLY A 172
ARG A 171
LEU A  92
 None
 0.61A 2vctC-3sggA:
undetectable		 2vctC-3sggA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ILE A 231
ALA A 292
LEU A 227
LEU A 287
ILE A 335
HIS A  61
 None
 1.36A 3gwsX-3sggA:
undetectable		 3gwsX-3sggA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 SER A 159
THR A 150
GLU A 200
ASP A 218
 None
 1.43A 3tm4A-3sggA:
undetectable		 3tm4A-3sggA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 SER A 159
THR A 150
GLU A 200
ASP A 218
 None
 1.42A 3tm4B-3sggA:
undetectable		 3tm4B-3sggA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 534
VAL A 540
PHE A 327
VAL A 530
HIS A 323
 None
 1.38A 3u9fH-3sggA:
undetectable
3u9fI-3sggA:
undetectable		 3u9fH-3sggA:
18.24
3u9fI-3sggA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 534
VAL A 540
PHE A 327
VAL A 530
HIS A 323
 None
 1.35A 3u9fJ-3sggA:
undetectable
3u9fK-3sggA:
undetectable		 3u9fJ-3sggA:
18.24
3u9fK-3sggA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 534
VAL A 540
PHE A 327
VAL A 530
HIS A 323
 None
 1.33A 3u9fN-3sggA:
undetectable
3u9fO-3sggA:
undetectable		 3u9fN-3sggA:
18.24
3u9fO-3sggA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 HIS A 323
LEU A 534
VAL A 540
PHE A 327
VAL A 530
 None
 1.39A 3u9fP-3sggA:
undetectable
3u9fS-3sggA:
undetectable		 3u9fP-3sggA:
18.24
3u9fS-3sggA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 364
ILE A 335
ALA A 336
GLY A 107
ALA A 371
 None
 0.85A 4enhA-3sggA:
undetectable		 4enhA-3sggA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 285
TYR A 408
PRO A 288
 None
 0.90A 4k8cA-3sggA:
undetectable		 4k8cA-3sggA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 285
TYR A 408
PRO A 288
 None
 0.89A 4kahA-3sggA:
undetectable		 4kahA-3sggA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 285
TYR A 408
PRO A 288
 None
 0.89A 4kahB-3sggA:
undetectable		 4kahB-3sggA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 285
TYR A 408
PRO A 288
 None
 0.91A 4kanA-3sggA:
undetectable		 4kanA-3sggA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 285
TYR A 408
PRO A 288
 None
 0.90A 4kanB-3sggA:
undetectable		 4kanB-3sggA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 285
TYR A 408
PRO A 288
 None
 0.89A 4kbeA-3sggA:
undetectable		 4kbeA-3sggA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 285
TYR A 408
PRO A 288
 None
 0.90A 4kbeB-3sggA:
undetectable		 4kbeB-3sggA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLY A 341
TRP A 340
ALA A 336
LEU A 339
ALA A  93
 None
 1.22A 4l6v1-3sggA:
undetectable
4l6v6-3sggA:
undetectable		 4l6v1-3sggA:
19.92
4l6v6-3sggA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 285
TYR A 408
PRO A 288
 None
 0.88A 4lbgA-3sggA:
undetectable		 4lbgA-3sggA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 285
TYR A 408
PRO A 288
 None
 0.90A 4lbgB-3sggA:
undetectable		 4lbgB-3sggA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 502
HIS A 323
SER A 501
 None
 0.83A 4mjwA-3sggA:
undetectable
4mjwB-3sggA:
undetectable		 4mjwA-3sggA:
20.74
4mjwB-3sggA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 501
ARG A 502
HIS A 323
 None
 0.82A 4mjwA-3sggA:
undetectable
4mjwB-3sggA:
undetectable		 4mjwA-3sggA:
20.74
4mjwB-3sggA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 11 ILE A 450
LYS A 440
SER A 393
ILE A 395
ILE A 426
 None
 1.32A 4p68A-3sggA:
undetectable		 4p68A-3sggA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ALA A 236
LEU A  55
ARG A  57
ILE A 231
 None
 0.61A 4ubsA-3sggA:
undetectable		 4ubsA-3sggA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A 179
ALA A 174
VAL A 134
ILE A 143
 None
 0.95A 4xe3A-3sggA:
undetectable		 4xe3A-3sggA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A 179
ALA A 174
VAL A 134
ILE A 143
 None
 0.94A 4xe3B-3sggA:
undetectable		 4xe3B-3sggA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 332
HIS A  61
LEU A 372
LEU A 287
TYR A 263
 None
 1.08A 4xldA-3sggA:
undetectable		 4xldA-3sggA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 388
HIS A  61
LEU A 372
LEU A 287
TYR A 263
 None
 1.37A 4xldA-3sggA:
undetectable		 4xldA-3sggA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 9 VAL A 517
VAL A 515
ILE A 531
PHE A 354
LEU A 356
 None
 1.33A 5e4dA-3sggA:
undetectable		 5e4dA-3sggA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 161
ASP A 290
GLY A 266
 None
 0.58A 5fctB-3sggA:
undetectable		 5fctB-3sggA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A  85
LEU A 130
SER A 178
VAL A 175
ASP A  80
 None
 1.12A 5nnaA-3sggA:
2.2		 5nnaA-3sggA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A  85
LEU A 130
SER A 178
VAL A 175
ASP A  80
 None
 1.13A 5nnaD-3sggA:
2.1		 5nnaD-3sggA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 SER A 390
ARG A 462
ASP A 460
ASP A 428
 None
 0.98A 5zw4A-3sggA:
undetectable		 5zw4A-3sggA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 9 VAL A 530
VAL A 540
GLY A 357
LEU A 356
VAL A 515
 None
 1.29A 6czmA-3sggA:
undetectable
6czmB-3sggA:
undetectable		 6czmA-3sggA:
22.30
6czmB-3sggA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 9 VAL A 530
VAL A 540
GLY A 357
LEU A 356
VAL A 515
 None
 1.28A 6czmB-3sggA:
undetectable
6czmC-3sggA:
undetectable		 6czmB-3sggA:
22.30
6czmC-3sggA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 9 VAL A 530
VAL A 540
GLY A 357
LEU A 356
VAL A 515
 None
 1.32A 6czmD-3sggA:
undetectable
6czmE-3sggA:
undetectable		 6czmD-3sggA:
22.30
6czmE-3sggA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 10 VAL A 530
VAL A 540
GLY A 357
LEU A 356
VAL A 515
 None
 1.27A 6czmE-3sggA:
undetectable
6czmF-3sggA:
undetectable		 6czmE-3sggA:
22.30
6czmF-3sggA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 456
TYR A 394
VAL A 478
GLU A 474
GLY A 459
 None
GOL  A 558 (-4.4A)
None
None
None
 1.34A 6gngA-3sggA:
2.6		 6gngA-3sggA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 535
HIS A 323
VAL A 325
TYR A 324
 None
 1.16A 6huoC-3sggA:
undetectable
6huoD-3sggA:
undetectable		 6huoC-3sggA:
10.82
6huoD-3sggA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3sgg HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASP A 433
TYR A 452
GLU A 474
ASP A 460
 None
 1.47A 6mn5A-3sggA:
undetectable		 6mn5A-3sggA:
9.90