SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sh5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		4 / 7 PHE A 152
VAL A 144
ILE A 138
GLY A 155
 None
 0.76A 11gsA-3sh5A:
undetectable		 11gsA-3sh5A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A  40
GLY A 158
GLY A  67
LEU A  68
GLY A  45
 None
 1.18A 1jhoA-3sh5A:
undetectable		 1jhoA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A 148
GLY A 150
GLY A  67
LEU A  46
GLY A  45
 None
 1.27A 1jhoA-3sh5A:
undetectable		 1jhoA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A  40
GLY A 158
GLY A  67
LEU A  68
GLY A  45
 None
 1.24A 1jhrA-3sh5A:
undetectable		 1jhrA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A 148
GLY A 150
GLY A  67
LEU A  46
GLY A  45
 None
 1.31A 1jhrA-3sh5A:
undetectable		 1jhrA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A  40
GLY A 158
GLY A  67
LEU A  68
GLY A  45
 None
 1.22A 1jhyA-3sh5A:
undetectable		 1jhyA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A  40
GLY A 158
GLY A  67
LEU A  68
GLY A  45
 None
 1.22A 1l4nA-3sh5A:
undetectable		 1l4nA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A 148
GLY A 150
GLY A  67
LEU A  46
GLY A  45
 None
 1.28A 1l4nA-3sh5A:
undetectable		 1l4nA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A  40
GLY A 158
GLY A  67
LEU A  68
GLY A  45
 None
 1.22A 1l5kA-3sh5A:
undetectable		 1l5kA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A 148
GLY A 150
GLY A  67
LEU A  46
GLY A  45
 None
 1.29A 1l5kA-3sh5A:
undetectable		 1l5kA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A  40
GLY A 158
GLY A  67
LEU A  68
GLY A  45
 None
 1.21A 1l5lA-3sh5A:
undetectable		 1l5lA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A 148
GLY A 150
GLY A  67
LEU A  46
GLY A  45
 None
 1.28A 1l5lA-3sh5A:
undetectable		 1l5lA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A  40
GLY A 158
GLY A  67
LEU A  68
GLY A  45
 None
 1.20A 1l5mA-3sh5A:
undetectable		 1l5mA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A 148
GLY A 150
GLY A  67
LEU A  46
GLY A  45
 None
 1.28A 1l5mA-3sh5A:
undetectable		 1l5mA-3sh5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 12 LEU A  46
LEU A  16
ALA A  17
LEU A 163
THR A 148
 None
 1.47A 1ya3A-3sh5A:
undetectable		 1ya3A-3sh5A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		4 / 8 PHE A 152
VAL A 144
ILE A 138
GLY A 155
 None
 0.74A 2gssA-3sh5A:
undetectable		 2gssA-3sh5A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		4 / 8 PHE A 152
VAL A 144
ILE A 138
GLY A 155
 None
 0.74A 2gssB-3sh5A:
undetectable		 2gssB-3sh5A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 10 THR A  40
LEU A  73
LEU A  68
GLY A  67
VAL A 160
 None
 1.13A 3lxiA-3sh5A:
undetectable		 3lxiA-3sh5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 11 THR A  40
LEU A  73
LEU A  68
GLY A  67
VAL A 160
 None
 1.13A 3lxiB-3sh5A:
undetectable		 3lxiB-3sh5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		4 / 6 PHE A  18
ILE A 138
ALA A 188
THR A 190
 None
 1.08A 3mdrB-3sh5A:
undetectable		 3mdrB-3sh5A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		4 / 8 PHE A 152
VAL A 144
ILE A 138
GLY A 155
 None
 0.70A 3n9jA-3sh5A:
undetectable		 3n9jA-3sh5A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 12 LEU A  46
PHE A  75
LEU A  66
GLY A  51
PHE A  23
 None
 1.13A 3tbgC-3sh5A:
undetectable		 3tbgC-3sh5A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A  40
LEU A  73
LEU A  68
GLY A  67
VAL A 160
 None
 1.15A 4c9kA-3sh5A:
undetectable		 4c9kA-3sh5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A  40
LEU A  73
LEU A  68
GLY A  67
VAL A 160
 None
 1.09A 4c9kB-3sh5A:
undetectable		 4c9kB-3sh5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 8 THR A  40
LEU A  73
LEU A  68
GLY A  67
VAL A 160
 None
 1.17A 4c9nA-3sh5A:
undetectable		 4c9nA-3sh5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 10 THR A  40
LEU A  73
LEU A  68
GLY A  67
VAL A 160
 None
 1.16A 4c9nB-3sh5A:
undetectable		 4c9nB-3sh5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 9 THR A  40
LEU A  73
LEU A  68
GLY A  67
VAL A 160
 None
 1.12A 4c9pA-3sh5A:
undetectable		 4c9pA-3sh5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 10 THR A  40
LEU A  73
LEU A  68
GLY A  67
VAL A 160
 None
 1.10A 4c9pB-3sh5A:
undetectable		 4c9pB-3sh5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		3 / 3 GLY A 125
PRO A 124
ALA A  84
 None
 0.46A 4qn9B-3sh5A:
undetectable		 4qn9B-3sh5A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 12 GLY A 155
GLY A  14
PHE A 152
THR A  42
TYR A   9
 None
 1.28A 5yf0A-3sh5A:
undetectable		 5yf0A-3sh5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)		 3sh5 LG3 PEPTIDE
(Homo
sapiens) 		5 / 11 PRO A  31
ARG A 122
PRO A 124
ALA A  84
TYR A  77
 None
 1.23A 6bm5A-3sh5A:
undetectable		 6bm5A-3sh5A:
20.00