SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3shd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		 3shd PHOSPHATASE NUDJ
(Escherichia
coli) 		4 / 4 PHE A  84
TYR A 136
VAL A  20
LEU A  19
 None
 1.17A 3keeD-3shdA:
undetectable		 3keeD-3shdA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3shd PHOSPHATASE NUDJ
(Escherichia
coli) 		3 / 3 SER A 120
GLU A  55
GLU A  39
 None
SO4  A 157 ( 2.4A)
MN  A 155 ( 4.7A)
 0.74A 4ymgB-3shdA:
undetectable		 4ymgB-3shdA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3shd PHOSPHATASE NUDJ
(Escherichia
coli) 		4 / 4 ALA A  73
PRO A   4
LEU A  38
HIS A  37
 None
None
None
SO4  A 156 (-3.9A)
 1.47A 5eskA-3shdA:
undetectable		 5eskA-3shdA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3shd PHOSPHATASE NUDJ
(Escherichia
coli) 		5 / 12 GLU A  55
ASN A  32
LEU A 118
ALA A 115
ASN A 117
 SO4  A 157 ( 2.4A)
SO4  A 158 ( 3.5A)
None
None
None
 1.30A 5kbwA-3shdA:
undetectable		 5kbwA-3shdA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3shd PHOSPHATASE NUDJ
(Escherichia
coli) 		5 / 12 GLU A  55
ASN A  32
LEU A 118
ALA A 115
ASN A 117
 SO4  A 157 ( 2.4A)
SO4  A 158 ( 3.5A)
None
None
None
 1.35A 5kc4E-3shdA:
undetectable		 5kc4E-3shdA:
20.00