SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3shp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 5 SER A  83
THR A 120
GLU A  76
GLY A  78
 None
 0.96A 1icrA-3shpA:
undetectable
1icrB-3shpA:
undetectable		 1icrA-3shpA:
23.53
1icrB-3shpA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 5 GLU A  76
GLY A  78
SER A  83
THR A 120
 None
 0.96A 1icrA-3shpA:
undetectable
1icrB-3shpA:
undetectable		 1icrA-3shpA:
23.53
1icrB-3shpA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 6 SER A  83
THR A 120
GLU A  76
GLY A  78
 None
 0.92A 1icuA-3shpA:
undetectable
1icuB-3shpA:
undetectable		 1icuA-3shpA:
23.53
1icuB-3shpA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 6 GLU A  76
GLY A  78
SER A  83
THR A 120
 None
 0.94A 1icuA-3shpA:
undetectable
1icuB-3shpA:
undetectable		 1icuA-3shpA:
23.53
1icuB-3shpA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 6 SER A  83
THR A 120
GLU A  76
GLY A  78
 None
 0.93A 1icuC-3shpA:
undetectable
1icuD-3shpA:
undetectable		 1icuC-3shpA:
23.53
1icuD-3shpA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 5 SER A  83
THR A 120
GLU A  76
GLY A  78
 None
 0.95A 1icvC-3shpA:
undetectable
1icvD-3shpA:
undetectable		 1icvC-3shpA:
23.53
1icvD-3shpA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 5 GLU A  76
GLY A  78
SER A  83
THR A 120
 None
 0.93A 1icvC-3shpA:
undetectable
1icvD-3shpA:
undetectable		 1icvC-3shpA:
23.53
1icvD-3shpA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 6 SER A  83
THR A 120
GLU A  76
GLY A  78
 None
 0.95A 1kqbA-3shpA:
undetectable
1kqbB-3shpA:
undetectable		 1kqbA-3shpA:
21.43
1kqbB-3shpA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 5 GLU A  76
GLY A  78
SER A  83
THR A 120
 None
 0.92A 1kqbA-3shpA:
undetectable
1kqbB-3shpA:
undetectable		 1kqbA-3shpA:
21.43
1kqbB-3shpA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 6 SER A  83
THR A 120
GLU A  76
GLY A  78
 None
 0.97A 1kqbC-3shpA:
undetectable
1kqbD-3shpA:
undetectable		 1kqbC-3shpA:
21.43
1kqbD-3shpA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 6 GLU A  76
GLY A  78
SER A  83
THR A 120
 None
 0.94A 1kqbC-3shpA:
undetectable
1kqbD-3shpA:
undetectable		 1kqbC-3shpA:
21.43
1kqbD-3shpA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		3 / 3 TRP A 109
HIS A  57
MET A   1
 None
 1.40A 1l5qB-3shpA:
undetectable		 1l5qB-3shpA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 7 PHE A  86
ARG A  85
ARG A  74
ALA A 102
 None
 1.31A 6b89A-3shpA:
undetectable		 6b89A-3shpA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		3 / 3 GLU A  45
ASP A  50
PRO A  51
 None
 0.80A 6berA-3shpA:
undetectable		 6berA-3shpA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3shp PUTATIVE
ACETYLTRANSFERASE
STHE_0691
(Sphaerobacter
thermophilus) 		4 / 8 ASP A  94
ARG A 129
ARG A  99
ARG A  38
 None
 1.26A 6fbvD-3shpA:
undetectable		 6fbvD-3shpA:
8.51