SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3shq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3shq UBLCP1
(Drosophila
melanogaster) 		5 / 12 PHE A 303
ILE A 296
PHE A 172
VAL A 210
ILE A 182
 None
 1.07A 3em0B-3shqA:
undetectable		 3em0B-3shqA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_B_URFB521_1
(RNA DEPENDENT RNA
POLYMERASE)		 3shq UBLCP1
(Drosophila
melanogaster) 		4 / 4 ARG A 258
ASP A 146
ASP A 255
ASP A 148
 None
MG  A 321 (-2.5A)
MG  A 321 (-2.7A)
MG  A 321 (-2.9A)
 1.37A 3naiB-3shqA:
undetectable		 3naiB-3shqA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_C_URFC521_1
(RNA DEPENDENT RNA
POLYMERASE)		 3shq UBLCP1
(Drosophila
melanogaster) 		4 / 5 ASP A 255
ASP A 146
ASP A 254
ARG A 258
 MG  A 321 (-2.7A)
MG  A 321 (-2.5A)
MG  A 321 ( 4.5A)
None
 1.42A 3naiC-3shqA:
undetectable		 3naiC-3shqA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 3shq UBLCP1
(Drosophila
melanogaster) 		5 / 12 LEU A 293
LEU A 143
LEU A 142
MET A 211
VAL A 210
 None
 1.24A 3zqtA-3shqA:
undetectable		 3zqtA-3shqA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3shq UBLCP1
(Drosophila
melanogaster) 		4 / 7 ALA A 297
ILE A 251
LEU A 306
PHE A 303
 None
 1.03A 4uymA-3shqA:
undetectable		 4uymA-3shqA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 3shq UBLCP1
(Drosophila
melanogaster) 		4 / 7 ASP A 255
ILE A 256
THR A 150
LYS A 233
 MG  A 321 (-2.7A)
None
None
None
 1.11A 4zxiA-3shqA:
undetectable		 4zxiA-3shqA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3shq UBLCP1
(Drosophila
melanogaster) 		4 / 6 LEU A 306
SER A 266
PRO A 264
PHE A 260
 None
 1.30A 5b8iA-3shqA:
undetectable		 5b8iA-3shqA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 3shq UBLCP1
(Drosophila
melanogaster) 		4 / 5 LEU A 286
LEU A 145
THR A 174
ARG A 198
 None
 1.11A 6ew0F-3shqA:
undetectable		 6ew0F-3shqA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 3shq UBLCP1
(Drosophila
melanogaster) 		4 / 6 GLU A  33
ARG A  36
VAL A 121
PRO A 234
 None
 1.37A 6fgdA-3shqA:
undetectable		 6fgdA-3shqA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3shq UBLCP1
(Drosophila
melanogaster) 		3 / 3 PHE A  35
ARG A  36
GLN A  39
 None
 1.16A 6g1pB-3shqA:
undetectable		 6g1pB-3shqA:
20.95