SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3shs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGN_A_ACTA1181_0 (WNT INHIBITORY FACTOR 1)	3shs	HOC HEAD OUTER CAPSID PROTEIN (Escherichia virus RB49)	3 / 3	TYR A 206 VAL A 186 THR A 294	None	0.88A	2ygnA-3shsA: undetectable	2ygnA-3shsA: 16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA153_0 (ILEAL BILE ACID-BINDING PROTEIN)	3shs	HOC HEAD OUTER CAPSID PROTEIN (Escherichia virus RB49)	4 / 4	ILE A 283 THR A 223 LYS A 225 TYR A 103	None	1.49A	3elzA-3shsA: 1.1	3elzA-3shsA: 19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ARC_A_LEUA1001_0 (LEUCINE--TRNA LIGASE)	3shs	HOC HEAD OUTER CAPSID PROTEIN (Escherichia virus RB49)	4 / 7	LEU A 92 TYR A 128 SER A 171 HIS A 131	None	1.34A	4arcA-3shsA: undetectable	4arcA-3shsA: 15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P6X_I_HCYI900_2 (GLUCOCORTICOID RECEPTOR)	3shs	HOC HEAD OUTER CAPSID PROTEIN (Escherichia virus RB49)	3 / 3	MET A 184 MET A 180 TYR A 280	None	1.15A	4p6xI-3shsA: undetectable	4p6xI-3shsA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GB9_A_ACTA508_0 (MOLYBDOPTERIN BIOSYNTHESIS PROTEIN CNX1)	3shs	HOC HEAD OUTER CAPSID PROTEIN (Escherichia virus RB49)	3 / 3	VAL A 290 ALA A 182 GLN A 281	None	0.31A	6gb9A-3shsA: undetectable	6gb9A-3shsA: 23.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YGN_A_ACTA1181_0","WNT INHIBITORY FACTOR 1","3shs","HOC HEAD OUTER CAPSID PROTEIN","Escherichia virus RB49",3,"TYR A 206;VAL A 186;THR A 294","None","0.88A","2ygnA-3shsA:undetectable","2ygnA-3shsA:16.78"],["3ELZ_A_CHDA153_0","ILEAL BILE ACID-BINDING PROTEIN","3shs","HOC HEAD OUTER CAPSID PROTEIN","Escherichia virus RB49",4,"ILE A 283;THR A 223;LYS A 225;TYR A 103","None","1.49A","3elzA-3shsA:1.1","3elzA-3shsA:19.28"],["4ARC_A_LEUA1001_0","LEUCINE--TRNA LIGASE","3shs","HOC HEAD OUTER CAPSID PROTEIN","Escherichia virus RB49",4,"LEU A  92;TYR A 128;SER A 171;HIS A 131","None","1.34A","4arcA-3shsA:undetectable","4arcA-3shsA:15.53"],["4P6X_I_HCYI900_2","GLUCOCORTICOID RECEPTOR","3shs","HOC HEAD OUTER CAPSID PROTEIN","Escherichia virus RB49",3,"MET A 184;MET A 180;TYR A 280","None","1.15A","4p6xI-3shsA:undetectable","4p6xI-3shsA:21.43"],["6GB9_A_ACTA508_0","MOLYBDOPTERIN BIOSYNTHESIS PROTEIN CNX1","3shs","HOC HEAD OUTER CAPSID PROTEIN","Escherichia virus RB49",3,"VAL A 290;ALA A 182;GLN A 281","None","0.31A","6gb9A-3shsA:undetectable","6gb9A-3shsA:23.74"]]