SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sjn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		4 / 4 ILE A 100
MET A  86
VAL A  30
GLY A  99
 None
 1.11A 1e06B-3sjnA:
undetectable		 1e06B-3sjnA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		4 / 8 PRO A 227
VAL A 228
SER A 201
ALA A 230
 None
 0.91A 2v32A-3sjnA:
undetectable
2v32B-3sjnA:
undetectable		 2v32A-3sjnA:
21.84
2v32B-3sjnA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		4 / 8 PRO A 227
VAL A 228
SER A 201
ALA A 230
 None
 0.94A 2v32A-3sjnA:
undetectable
2v32B-3sjnA:
undetectable		 2v32A-3sjnA:
21.84
2v32B-3sjnA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 12 ILE A 299
GLN A 272
SER A 312
GLY A 302
ASN A 222
 None
None
None
None
UNL  A 375 ( 2.9A)
 1.07A 2zw9A-3sjnA:
2.1		 2zw9A-3sjnA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 10 ALA A 311
ILE A 360
GLY A 306
ALA A 105
ILE A 108
 None
 0.96A 3ekwA-3sjnA:
undetectable		 3ekwA-3sjnA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 10 ILE A   7
ILE A  55
VAL A  51
GLY A  99
LEU A  70
 None
 1.08A 3elzC-3sjnA:
undetectable		 3elzC-3sjnA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 10 ILE A   7
ILE A  55
VAL A  51
GLY A  99
LEU A  70
 None
 1.19A 3em0A-3sjnA:
undetectable		 3em0A-3sjnA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 12 LEU A 126
GLY A 115
LEU A 362
ILE A 281
ILE A  29
 None
 0.85A 3frqB-3sjnA:
undetectable		 3frqB-3sjnA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		4 / 8 LEU A 316
ALA A 351
GLY A 302
PRO A 300
 None
 0.84A 3ny4A-3sjnA:
undetectable		 3ny4A-3sjnA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 11 ARG A 371
ILE A 108
GLY A  40
VAL A  39
ILE A  29
 None
 1.02A 3oxxD-3sjnA:
undetectable		 3oxxD-3sjnA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		4 / 8 SER A 312
VAL A 313
VAL A  41
GLY A  42
 None
 0.99A 4mk4A-3sjnA:
undetectable		 4mk4A-3sjnA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 9 ASP A 178
VAL A 185
ALA A 184
GLY A 167
PHE A 166
 None
 1.29A 4mmeB-3sjnA:
undetectable		 4mmeB-3sjnA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 9 ASP A 178
VAL A 185
ALA A 184
GLY A 167
PHE A 166
 None
 1.30A 4mmfB-3sjnA:
undetectable		 4mmfB-3sjnA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 9 ALA A  44
ILE A 100
GLY A 279
ILE A  55
VAL A  51
 None
 1.08A 4nptA-3sjnA:
undetectable		 4nptA-3sjnA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		4 / 4 LYS A 165
ASN A 149
ASP A 144
ASP A 198
 MG  A 374 ( 4.2A)
None
None
MG  A 374 (-2.5A)
 1.15A 4o1eB-3sjnA:
3.2		 4o1eB-3sjnA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		4 / 6 LEU A 199
MET A 212
LEU A 221
ILE A 270
 None
 1.10A 4okxA-3sjnA:
undetectable		 4okxA-3sjnA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		4 / 6 LEU A 298
HIS A 301
TYR A 137
GLU A 326
 None
MG  A 374 ( 4.9A)
None
None
 1.09A 4pahA-3sjnA:
undetectable		 4pahA-3sjnA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		3 / 3 GLU A 283
TRP A 111
ASN A  84
 None
 1.00A 5dv4A-3sjnA:
undetectable		 5dv4A-3sjnA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		4 / 7 GLY A 302
PHE A 303
GLU A 326
ASP A  45
 None
 1.05A 5n5dB-3sjnA:
undetectable		 5n5dB-3sjnA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_1
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 12 GLY A 160
PHE A 161
PHE A 335
PHE A 345
THR A 139
 None
 1.35A 5nknA-3sjnA:
undetectable		 5nknA-3sjnA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 12 ILE A 367
VAL A  30
ILE A 307
LEU A 334
THR A 305
 None
 1.25A 5tiwB-3sjnA:
undetectable		 5tiwB-3sjnA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 12 GLY A 302
VAL A 122
LEU A 126
GLY A 280
ILE A 108
 None
 1.14A 5vooA-3sjnA:
7.5		 5vooA-3sjnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 12 GLY A 302
VAL A 122
LEU A 126
GLY A 280
ILE A 108
 None
 1.11A 5vooB-3sjnA:
5.7		 5vooB-3sjnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 12 GLY A 302
VAL A 122
LEU A 126
GLY A 280
ILE A 108
 None
 1.15A 5vooC-3sjnA:
4.5		 5vooC-3sjnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 12 GLY A 302
VAL A 122
LEU A 126
GLY A 280
ILE A 108
 None
 1.15A 5vooD-3sjnA:
7.2		 5vooD-3sjnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 12 GLY A 302
VAL A 122
LEU A 126
GLY A 280
ILE A 108
 None
 1.16A 5vooE-3sjnA:
8.1		 5vooE-3sjnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		5 / 12 GLY A 302
VAL A 122
LEU A 126
GLY A 280
ILE A 108
 None
 1.17A 5vooF-3sjnA:
9.3		 5vooF-3sjnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		3 / 3 LYS A  85
LEU A  82
ARG A  81
 None
 0.92A 5yw0A-3sjnA:
undetectable		 5yw0A-3sjnA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		4 / 8 GLY A  97
ILE A 100
ASP A 274
PRO A 273
 None
 0.78A 6ag0A-3sjnA:
8.8		 6ag0A-3sjnA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		4 / 8 GLY A  97
ILE A 100
ASP A 274
PRO A 273
 None
 0.76A 6ag0C-3sjnA:
5.6		 6ag0C-3sjnA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Shewanella
pealeana) 		4 / 7 SER A 252
ALA A 230
ILE A 247
ALA A 248
 None
 0.92A 6ma7A-3sjnA:
undetectable		 6ma7A-3sjnA:
11.53