SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sk7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3sk7 PROTEIN SEQA
(Vibrio
cholerae) 		4 / 7 GLU A  77
PHE A  78
HIS A  96
VAL A 143
 None
 1.07A 4a97D-3sk7A:
undetectable		 4a97D-3sk7A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 3sk7 PROTEIN SEQA
(Vibrio
cholerae) 		4 / 5 VAL A 115
THR A 123
ASN A 120
ASP A 119
 None
 1.31A 5m0iB-3sk7A:
undetectable		 5m0iB-3sk7A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3sk7 PROTEIN SEQA
(Vibrio
cholerae) 		4 / 6 GLN A 154
PHE A  88
LEU A  92
PHE A 103
 None
 1.12A 5z84P-3sk7A:
undetectable
5z84W-3sk7A:
undetectable		 5z84P-3sk7A:
16.48
5z84W-3sk7A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3sk7 PROTEIN SEQA
(Vibrio
cholerae) 		4 / 6 GLN A 154
PHE A  88
LEU A  92
PHE A 103
 None
 1.12A 5z85P-3sk7A:
undetectable
5z85W-3sk7A:
undetectable		 5z85P-3sk7A:
16.48
5z85W-3sk7A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3sk7 PROTEIN SEQA
(Vibrio
cholerae) 		4 / 6 GLN A 154
PHE A  88
LEU A  92
PHE A 103
 None
 1.08A 5z86C-3sk7A:
undetectable
5z86J-3sk7A:
undetectable		 5z86C-3sk7A:
16.48
5z86J-3sk7A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3sk7 PROTEIN SEQA
(Vibrio
cholerae) 		4 / 6 GLN A 154
PHE A  88
LEU A  92
PHE A 103
 None
 1.09A 5z86P-3sk7A:
undetectable
5z86W-3sk7A:
undetectable		 5z86P-3sk7A:
16.48
5z86W-3sk7A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3sk7 PROTEIN SEQA
(Vibrio
cholerae) 		4 / 6 GLN A 154
PHE A  88
LEU A  92
PHE A 103
 None
 1.07A 5zcpC-3sk7A:
undetectable
5zcpJ-3sk7A:
undetectable		 5zcpC-3sk7A:
16.48
5zcpJ-3sk7A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3sk7 PROTEIN SEQA
(Vibrio
cholerae) 		4 / 6 GLN A 154
PHE A  88
LEU A  92
PHE A 103
 None
 1.12A 5zcpP-3sk7A:
undetectable
5zcpW-3sk7A:
undetectable		 5zcpP-3sk7A:
16.48
5zcpW-3sk7A:
16.81