SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3skp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		4 / 7 ARG A 644
ALA A 409
PRO A 406
ALA A 586
 SO4  A 682 (-3.8A)
None
None
None
 0.94A 2zgwA-3skpA:
undetectable		 2zgwA-3skpA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 GLU A 351
SER A 390
VAL A 587
 None
 0.83A 3eeoA-3skpA:
undetectable		 3eeoA-3skpA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		4 / 6 ASN A 383
MET A 382
ILE A 381
GLU A 385
 None
 1.48A 3kp6A-3skpA:
0.9
3kp6B-3skpA:
undetectable		 3kp6A-3skpA:
17.66
3kp6B-3skpA:
17.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		5 / 7 GLY A 425
PRO A 583
ASN A 584
TYR A 650
GLY A 652
 None
None
None
None
SO4  A 683 (-3.4A)
 0.73A 3tajA-3skpA:
24.5		 3tajA-3skpA:
60.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		4 / 5 GLY A 425
PRO A 583
ASN A 584
TYR A 650
 None
 0.60A 3u8qA-3skpA:
25.8		 3u8qA-3skpA:
59.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		4 / 6 GLY A 425
PRO A 583
GLY A 652
TYR A 655
 None
None
SO4  A 683 (-3.4A)
None
 0.75A 4dxuA-3skpA:
25.6		 4dxuA-3skpA:
59.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		5 / 9 GLY A 425
PRO A 583
TYR A 650
GLY A 652
TYR A 655
 None
None
None
SO4  A 683 (-3.4A)
None
 0.82A 4fimA-3skpA:
25.4		 4fimA-3skpA:
59.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		5 / 6 GLY A 425
PRO A 583
ASN A 584
TYR A 650
GLY A 652
 None
None
None
None
SO4  A 683 (-3.4A)
 0.80A 4fjpA-3skpA:
25.7		 4fjpA-3skpA:
59.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		4 / 7 GLY A 425
PRO A 583
ASN A 584
TYR A 650
 None
 0.48A 4forA-3skpA:
24.5		 4forA-3skpA:
59.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		4 / 7 PRO A 583
ASN A 584
TYR A 650
GLY A 652
 None
None
None
SO4  A 683 (-3.4A)
 0.46A 4forA-3skpA:
24.5		 4forA-3skpA:
59.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 PRO A 583
TYR A 650
GLY A 652
 None
None
SO4  A 683 (-3.4A)
 0.44A 4g2zA-3skpA:
25.7		 4g2zA-3skpA:
59.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		5 / 12 ALA A 428
GLY A 425
GLU A 410
ALA A 409
TYR A 650
 None
 1.10A 4pclA-3skpA:
undetectable		 4pclA-3skpA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		5 / 12 ALA A 428
GLY A 459
ILE A 471
MET A 464
GLY A 465
 None
 1.08A 4r29D-3skpA:
undetectable		 4r29D-3skpA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 ALA A 658
ASN A 661
LEU A 662
 None
 0.41A 5i1oC-3skpA:
undetectable		 5i1oC-3skpA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 ALA A 658
ASN A 661
LEU A 662
 None
 0.49A 5i1oA-3skpA:
undetectable		 5i1oA-3skpA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 ALA A 658
ASN A 661
LEU A 662
 None
 0.38A 5i1pA-3skpA:
undetectable		 5i1pA-3skpA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 ALA A 658
ASN A 661
LEU A 662
 None
 0.46A 5i1pD-3skpA:
undetectable		 5i1pD-3skpA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3skp SEROTRANSFERRIN
(Homo
sapiens) 		5 / 9 MET A 464
ARG A 456
TRP A 460
ALA A 453
ALA A 458
 None
SO4  A   1 (-4.8A)
None
None
None
 1.27A 6hqbB-3skpA:
undetectable		 6hqbB-3skpA:
13.06