SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3skq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3skq MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
38
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 394
PHE A 222
ILE A 395
SER A 354
 None
 0.97A 2a8tB-3skqA:
undetectable		 2a8tB-3skqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3skq MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
38
(Saccharomyces
cerevisiae) 		5 / 7 ILE A 395
PRO A 405
ILE A 204
LEU A 203
ILE A 402
 None
 1.14A 2q83A-3skqA:
undetectable		 2q83A-3skqA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 3skq MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
38
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 332
ASN A 333
SER A 382
 None
 0.92A 3lslA-3skqA:
undetectable
3lslD-3skqA:
undetectable		 3lslA-3skqA:
22.41
3lslD-3skqA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 3skq MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
38
(Saccharomyces
cerevisiae) 		3 / 3 SER A 382
ASP A 332
ASN A 333
 None
 0.84A 3lslA-3skqA:
undetectable
3lslD-3skqA:
undetectable		 3lslA-3skqA:
22.41
3lslD-3skqA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 3skq MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
38
(Saccharomyces
cerevisiae) 		4 / 5 VAL A 398
LEU A 198
ILE A 402
VAL A 253
 None
 0.98A 4a9kB-3skqA:
undetectable		 4a9kB-3skqA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 3skq MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
38
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 346
HIS A 238
ALA A 370
LEU A 340
LEU A 388
 None
 1.27A 4pbhA-3skqA:
undetectable		 4pbhA-3skqA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3skq MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
38
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 232
LYS A 224
SER A 227
 None
 1.45A 5odiA-3skqA:
undetectable		 5odiA-3skqA:
20.48