SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sks'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		3 / 3 GLN A  85
TYR A 224
ARG A 225
 None
 0.94A 1gtbA-3sksA:
undetectable		 1gtbA-3sksA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 HIS A 356
GLU A 357
HIS A 360
GLU A 384
TYR A 490
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
PO4  A 566 (-4.5A)
 0.40A 1j36A-3sksA:
22.9		 1j36A-3sksA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 HIS A 356
GLU A 357
HIS A 360
GLU A 384
TYR A 490
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
PO4  A 566 (-4.5A)
 0.40A 1j36B-3sksA:
23.0		 1j36B-3sksA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_A_X8ZA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		6 / 11 HIS A 356
GLU A 357
HIS A 360
GLU A 384
PHE A 420
TYR A 490
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
None
PO4  A 566 (-4.5A)
 0.48A 1j37A-3sksA:
22.9		 1j37A-3sksA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_B_X8ZB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		6 / 11 HIS A 356
GLU A 357
HIS A 360
GLU A 384
PHE A 420
TYR A 490
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
None
PO4  A 566 (-4.5A)
 0.49A 1j37B-3sksA:
22.9		 1j37B-3sksA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		6 / 12 HIS A 356
GLU A 357
HIS A 360
GLU A 384
PHE A 420
TYR A 490
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
None
PO4  A 566 (-4.5A)
 0.49A 1o86A-3sksA:
6.9		 1o86A-3sksA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S2A_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 LEU A 518
HIS A 386
SER A 387
MET A 388
GLN A 111
 None
None
ZN  A 568 ( 3.7A)
None
None
 1.33A 1s2aA-3sksA:
undetectable		 1s2aA-3sksA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 8 GLU A 384
HIS A 356
HIS A 360
GLU A 357
 ZN  A 568 ( 2.0A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
 0.91A 1v7zA-3sksA:
undetectable		 1v7zA-3sksA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 8 GLU A 384
HIS A 356
HIS A 360
GLU A 357
 ZN  A 568 ( 2.0A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
 0.92A 1v7zB-3sksA:
undetectable		 1v7zB-3sksA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 8 GLU A 384
HIS A 356
HIS A 360
GLU A 357
 ZN  A 568 ( 2.0A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
 0.92A 1v7zC-3sksA:
undetectable		 1v7zC-3sksA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 8 GLU A 384
HIS A 356
HIS A 360
GLU A 357
 ZN  A 568 ( 2.0A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
 0.94A 1v7zD-3sksA:
undetectable		 1v7zD-3sksA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 8 GLU A 384
HIS A 356
HIS A 360
GLU A 357
 ZN  A 568 ( 2.0A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
 0.94A 1v7zE-3sksA:
undetectable		 1v7zE-3sksA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 8 GLU A 384
HIS A 356
HIS A 360
GLU A 357
 ZN  A 568 ( 2.0A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
 0.92A 1v7zF-3sksA:
undetectable		 1v7zF-3sksA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 HIS A 356
GLU A 357
HIS A 360
GLU A 384
TYR A 487
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
None
 0.80A 2c6nA-3sksA:
23.1		 2c6nA-3sksA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 HIS A 356
GLU A 357
HIS A 360
GLU A 384
TYR A 490
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
PO4  A 566 (-4.5A)
 0.38A 2c6nA-3sksA:
23.1		 2c6nA-3sksA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 HIS A 356
GLU A 357
HIS A 360
GLU A 384
TYR A 487
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
None
 0.82A 2c6nB-3sksA:
23.0		 2c6nB-3sksA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 HIS A 356
GLU A 357
HIS A 360
GLU A 384
TYR A 490
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
PO4  A 566 (-4.5A)
 0.52A 2c6nB-3sksA:
23.0		 2c6nB-3sksA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		3 / 3 GLN A 239
LYS A 546
VAL A 548
 None
 0.83A 2jfaB-3sksA:
undetectable		 2jfaB-3sksA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8Z_A_X8ZA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		6 / 11 HIS A 356
GLU A 357
HIS A 360
GLU A 384
PHE A 420
TYR A 490
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
None
PO4  A 566 (-4.5A)
 0.40A 2x8zA-3sksA:
23.5		 2x8zA-3sksA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 HIS A 356
GLU A 357
HIS A 360
GLU A 384
TYR A 490
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
PO4  A 566 (-4.5A)
 0.33A 2x91A-3sksA:
23.6		 2x91A-3sksA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 8 GLU A 384
HIS A 356
HIS A 360
GLU A 357
 ZN  A 568 ( 2.0A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
 0.90A 3a6jA-3sksA:
undetectable		 3a6jA-3sksA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 7 GLU A 384
HIS A 356
HIS A 360
GLU A 357
 ZN  A 568 ( 2.0A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
 0.88A 3a6jB-3sksA:
undetectable		 3a6jB-3sksA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 8 GLU A 384
HIS A 356
HIS A 360
GLU A 357
 ZN  A 568 ( 2.0A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
 0.89A 3a6jC-3sksA:
undetectable		 3a6jC-3sksA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 8 GLU A 384
HIS A 356
HIS A 360
GLU A 357
 ZN  A 568 ( 2.0A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
 0.92A 3a6jE-3sksA:
undetectable		 3a6jE-3sksA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 8 GLU A 384
HIS A 356
HIS A 360
GLU A 357
 ZN  A 568 ( 2.0A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
 0.88A 3a6jF-3sksA:
undetectable		 3a6jF-3sksA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		3 / 3 HIS A 356
GLU A 357
HIS A 360
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
 0.22A 3kecB-3sksA:
2.2		 3kecB-3sksA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 9 VAL A 233
PHE A 540
ILE A 488
ALA A 493
VAL A 425
 None
 1.24A 3me6C-3sksA:
undetectable		 3me6C-3sksA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 8 LEU A 185
TYR A 181
PHE A 184
TYR A 141
 None
 1.18A 3po7A-3sksA:
undetectable		 3po7A-3sksA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 VAL A 548
ILE A 244
TYR A 236
VAL A 425
LEU A 498
 None
 1.23A 4a84A-3sksA:
undetectable		 4a84A-3sksA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 7 ILE A 372
GLU A 374
PHE A 113
TYR A  91
 None
 0.86A 4a97D-3sksA:
2.5		 4a97D-3sksA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		6 / 11 HIS A 356
GLU A 357
HIS A 360
GLU A 384
PHE A 420
TYR A 490
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
None
PO4  A 566 (-4.5A)
 0.49A 4c2pA-3sksA:
23.3		 4c2pA-3sksA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 11 HIS A 356
GLU A 357
HIS A 360
GLU A 384
TYR A 487
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
None
 0.79A 4c2pA-3sksA:
23.3		 4c2pA-3sksA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 6 ILE A 452
ARG A 237
GLY A 424
HIS A 432
 None
 0.93A 4oltA-3sksA:
undetectable		 4oltA-3sksA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 6 LEU A 518
HIS A 360
HIS A 356
GLU A 384
 None
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
 0.80A 4pahA-3sksA:
undetectable		 4pahA-3sksA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 HIS A 356
GLU A 357
HIS A 360
GLU A 384
TYR A 490
 ZN  A 568 ( 3.3A)
PO4  A 566 (-3.2A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
PO4  A 566 (-4.5A)
 0.74A 4r7lA-3sksA:
7.0		 4r7lA-3sksA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 ASP A 428
THR A 379
ALA A 382
ALA A 493
TYR A 228
 None
 1.38A 4u15B-3sksA:
undetectable		 4u15B-3sksA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ACL_A_SASA1111_1
(MCG)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 7 TYR A 331
TYR A 365
GLU A 366
PHE A 370
 None
 1.16A 5aclA-3sksA:
undetectable		 5aclA-3sksA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		3 / 3 TYR A 196
TYR A 487
GLN A 431
 None
 0.99A 5jsdA-3sksA:
undetectable
5jsdB-3sksA:
undetectable		 5jsdA-3sksA:
21.50
5jsdB-3sksA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		3 / 3 TYR A 196
TYR A 487
GLN A 431
 None
 0.99A 5jsdB-3sksA:
undetectable
5jsdC-3sksA:
undetectable		 5jsdB-3sksA:
21.50
5jsdC-3sksA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 PHE A 500
ILE A 385
SER A 524
VAL A 533
PRO A 378
 None
 1.29A 5mlmA-3sksA:
undetectable		 5mlmA-3sksA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 5 TYR A 328
ALA A 324
GLN A  74
THR A  65
 None
 0.80A 5n0wB-3sksA:
undetectable		 5n0wB-3sksA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 5 TYR A 328
ALA A 324
GLN A  74
THR A  65
 None
 0.88A 5n4iA-3sksA:
undetectable		 5n4iA-3sksA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 ILE A 351
LEU A 400
PHE A 402
MET A 294
ASP A 283
 None
 1.17A 5x66A-3sksA:
undetectable
5x66B-3sksA:
undetectable		 5x66A-3sksA:
18.61
5x66B-3sksA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		5 / 12 ASN A 343
ILE A 150
PHE A 184
THR A  66
THR A  65
 None
 0.97A 6bbsA-3sksA:
undetectable		 6bbsA-3sksA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 3sks PUTATIVE
OLIGOENDOPEPTIDASE F
(Bacillus
anthracis) 		4 / 6 LEU A 518
HIS A 360
HIS A 356
GLU A 384
 None
ZN  A 568 ( 3.3A)
ZN  A 568 ( 3.3A)
ZN  A 568 ( 2.0A)
 0.76A 6pahA-3sksA:
undetectable		 6pahA-3sksA:
19.86