SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sku'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OKC_A_SAMA500_1 (TYPE I RESTRICTION ENZYME STYSJI M PROTEIN)	3sku	GLYCOPROTEIN D (Human alphaherpesvirus 1)	4 / 6	THR A 131 ARG A 36 ASN A 171 ASP A 172	None	1.33A	2okcA-3skuA: undetectable	2okcA-3skuA: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E72_A_SAMA400_0 (N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE)	3sku	GLYCOPROTEIN D (Human alphaherpesvirus 1)	5 / 12	PHE A 100 GLY A 162 ALA A 98 PRO A 109 LEU A 44	None	1.06A	5e72A-3skuA: undetectable	5e72A-3skuA: 22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_A_PCFA1801_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3sku	GLYCOPROTEIN D (Human alphaherpesvirus 1)	4 / 6	ILE A 217 ILE A 97 LEU A 167 PHE A 100	None	1.09A	5vkqA-3skuA: undetectable 5vkqB-3skuA: undetectable	5vkqA-3skuA: 9.62 5vkqB-3skuA: 9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_D_PCFD1807_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3sku	GLYCOPROTEIN D (Human alphaherpesvirus 1)	4 / 6	ILE A 217 ILE A 97 LEU A 167 PHE A 100	None	1.07A	5vkqA-3skuA: undetectable 5vkqD-3skuA: undetectable	5vkqA-3skuA: 9.62 5vkqD-3skuA: 9.62

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OKC_A_SAMA500_1","TYPE I RESTRICTION ENZYME STYSJI M PROTEIN","3sku","GLYCOPROTEIN D","Human alphaherpesvirus 1",4,"THR A 131;ARG A  36;ASN A 171;ASP A 172","None","1.33A","2okcA-3skuA:undetectable","2okcA-3skuA:20.35"],["5E72_A_SAMA400_0","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","3sku","GLYCOPROTEIN D","Human alphaherpesvirus 1",5,"PHE A 100;GLY A 162;ALA A  98;PRO A 109;LEU A  44","None","1.06A","5e72A-3skuA:undetectable","5e72A-3skuA:22.06"],["5VKQ_A_PCFA1801_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3sku","GLYCOPROTEIN D","Human alphaherpesvirus 1",4,"ILE A 217;ILE A  97;LEU A 167;PHE A 100","None","1.09A","5vkqA-3skuA:undetectable;5vkqB-3skuA:undetectable","5vkqA-3skuA:9.62;5vkqB-3skuA:9.62"],["5VKQ_D_PCFD1807_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3sku","GLYCOPROTEIN D","Human alphaherpesvirus 1",4,"ILE A 217;ILE A  97;LEU A 167;PHE A 100","None","1.07A","5vkqA-3skuA:undetectable;5vkqD-3skuA:undetectable","5vkqA-3skuA:9.62;5vkqD-3skuA:9.62"]]