SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sl9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LXE_B_TORB262_1 (CARBONIC ANHYDRASE 1)	3sl9	CATENIN BETA-1 (Homo sapiens)	5 / 12	HIS A 223 VAL A 195 LEU A 218 THR A 217 HIS A 219	None	1.39A	3lxeB-3sl9A: undetectable	3lxeB-3sl9A: 19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KHP_A_PARA1606_1 (16S RIBOSOMAL RNA 30S RIBOSOMAL PROTEIN S9 30S RIBOSOMAL PROTEIN S10)	3sl9	CATENIN BETA-1 (Homo sapiens)	3 / 3	TYR A 254 ARG A 212 SER A 250	None	1.11A	4khpI-3sl9A: undetectable 4khpJ-3sl9A: undetectable	4khpI-3sl9A: 21.66 4khpJ-3sl9A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0O_A_SAMA501_0 (PEPTIDE N-METHYLTRANSFERASE)	3sl9	CATENIN BETA-1 (Homo sapiens)	5 / 12	ILE A 231 GLY A 227 HIS A 224 SER A 222 VAL A 199	None	1.12A	5n0oA-3sl9A: undetectable	5n0oA-3sl9A: 18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0O_B_SAMB501_0 (PEPTIDE N-METHYLTRANSFERASE)	3sl9	CATENIN BETA-1 (Homo sapiens)	5 / 12	ILE A 231 GLY A 227 HIS A 224 SER A 222 VAL A 199	None	1.11A	5n0oB-3sl9A: undetectable	5n0oB-3sl9A: 18.46

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LXE_B_TORB262_1","CARBONIC ANHYDRASE 1","3sl9","CATENIN BETA-1","Homo sapiens",5,"HIS A 223;VAL A 195;LEU A 218;THR A 217;HIS A 219","None","1.39A","3lxeB-3sl9A:undetectable","3lxeB-3sl9A:19.77"],["4KHP_A_PARA1606_1","16S RIBOSOMAL RNA;30S RIBOSOMAL PROTEIN S9;30S RIBOSOMAL PROTEIN S10","3sl9","CATENIN BETA-1","Homo sapiens",3,"TYR A 254;ARG A 212;SER A 250","None","1.11A","4khpI-3sl9A:undetectable;4khpJ-3sl9A:undetectable","4khpI-3sl9A:21.66;4khpJ-3sl9A:20.00"],["5N0O_A_SAMA501_0","PEPTIDE N-METHYLTRANSFERASE","3sl9","CATENIN BETA-1","Homo sapiens",5,"ILE A 231;GLY A 227;HIS A 224;SER A 222;VAL A 199","None","1.12A","5n0oA-3sl9A:undetectable","5n0oA-3sl9A:18.46"],["5N0O_B_SAMB501_0","PEPTIDE N-METHYLTRANSFERASE","3sl9","CATENIN BETA-1","Homo sapiens",5,"ILE A 231;GLY A 227;HIS A 224;SER A 222;VAL A 199","None","1.11A","5n0oB-3sl9A:undetectable","5n0oB-3sl9A:18.46"]]