SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3slc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 8 ARG A 178
GLN A 155
HIS A 186
TYR A 317
 None
 1.29A 1nx9A-3slcA:
undetectable		 1nx9A-3slcA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 8 ARG A 178
GLN A 155
HIS A 186
TYR A 317
 None
 1.27A 1nx9B-3slcA:
undetectable		 1nx9B-3slcA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 8 ARG A 178
GLN A 155
HIS A 186
TYR A 317
 None
 1.26A 1nx9C-3slcA:
undetectable		 1nx9C-3slcA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 8 ARG A 178
GLN A 155
HIS A 186
TYR A 317
 None
 1.27A 1nx9D-3slcA:
undetectable		 1nx9D-3slcA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		3 / 3 THR A 385
ASP A 394
SER A 396
 None
 0.79A 2nxeA-3slcA:
undetectable		 2nxeA-3slcA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		3 / 3 THR A 385
ASP A 394
SER A 396
 None
 0.77A 2nxeB-3slcA:
undetectable		 2nxeB-3slcA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 6 SER A 108
VAL A 103
TYR A  99
ASP A 106
 None
 1.45A 2x45A-3slcA:
undetectable		 2x45A-3slcA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_0
(N,N-DIMETHYLTRANSFER
ASE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		5 / 12 GLY A 180
HIS A 182
ARG A 221
SER A 218
TYR A 317
 None
 1.26A 3bxoB-3slcA:
undetectable		 3bxoB-3slcA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		5 / 9 LEU A  30
PHE A  18
ILE A  44
ALA A  66
THR A  73
 None
 1.28A 3mdtA-3slcA:
undetectable		 3mdtA-3slcA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3slc ACETATE KINASE
(Salmonella
enterica) 		5 / 12 MET A  48
LEU A  30
LEU A   5
LEU A   7
ILE A  74
 None
 1.17A 3olsB-3slcA:
undetectable		 3olsB-3slcA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 4 LEU A 277
GLY A 275
GLY A 278
THR A 280
 None
 0.91A 3si7A-3slcA:
undetectable		 3si7A-3slcA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 5 LEU A 211
GLY A 332
THR A 385
VAL A 189
 None
 1.06A 3wrkD-3slcA:
undetectable		 3wrkD-3slcA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 5 PHE A 354
ILE A 314
GLY A 315
THR A 318
 None
 0.65A 4ejjC-3slcA:
undetectable		 4ejjC-3slcA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3slc ACETATE KINASE
(Salmonella
enterica) 		3 / 3 LYS A 312
TYR A 313
ARG A 309
 None
 1.35A 4gc9A-3slcA:
undetectable		 4gc9A-3slcA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		5 / 10 ASN A 386
GLY A 333
ILE A 334
VAL A 329
VAL A 189
 None
 1.01A 4j5jB-3slcA:
undetectable		 4j5jB-3slcA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 6 GLY A 215
ASP A 150
PRO A 234
ARG A 243
 None
 1.25A 4lajA-3slcA:
undetectable
4lajB-3slcA:
undetectable		 4lajA-3slcA:
22.94
4lajB-3slcA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 5 THR A 385
THR A 331
THR A 228
HIS A 154
 None
 1.29A 4pgfB-3slcA:
undetectable		 4pgfB-3slcA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3slc ACETATE KINASE
(Salmonella
enterica) 		5 / 10 THR A 331
ILE A 207
GLN A 191
VAL A 201
LEU A 204
 None
 1.45A 4r3aB-3slcA:
undetectable		 4r3aB-3slcA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 8 ILE A 372
MET A 303
LEU A 211
ILE A 334
 None
 0.92A 5ieoA-3slcA:
undetectable		 5ieoA-3slcA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 6 PRO A 234
GLY A 214
ARG A 243
ARG A  91
 None
 1.45A 5jcnB-3slcA:
undetectable		 5jcnB-3slcA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		5 / 12 TYR A 162
GLY A 231
GLN A 155
ARG A 178
ASP A 227
 None
 1.23A 6bxlB-3slcA:
undetectable		 6bxlB-3slcA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 3slc ACETATE KINASE
(Salmonella
enterica) 		5 / 12 TYR A 162
LEU A 232
GLY A 231
ARG A 178
ASP A 227
 None
 1.11A 6bxlB-3slcA:
undetectable		 6bxlB-3slcA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 5 THR A 331
THR A 228
HIS A 154
GLY A 214
 None
 1.08A 6gbnC-3slcA:
undetectable		 6gbnC-3slcA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 5 LEU A 232
TYR A 179
ILE A 110
GLY A 175
 None
 0.99A 6hd6A-3slcA:
undetectable		 6hd6A-3slcA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3slc ACETATE KINASE
(Salmonella
enterica) 		4 / 5 LEU A 310
TYR A 306
ILE A 251
GLY A 215
 None
 0.89A 6hd6A-3slcA:
undetectable		 6hd6A-3slcA:
11.92