SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3slg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		3 / 3 ASP A  35
ASP A  39
ASP A  56
 None
 0.77A 1ej0A-3slgA:
6.4		 1ej0A-3slgA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		4 / 8 ASP A  56
ILE A  57
THR A  58
LEU A  96
 None
 0.68A 1hmyA-3slgA:
4.6		 1hmyA-3slgA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_A_BEZA1501_0
(RAS-RELATED PROTEIN
RAB-9A)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		4 / 5 ILE A  15
TRP A 180
LEU A  77
PRO A 118
 None
 1.48A 1s8fA-3slgA:
4.5
1s8fB-3slgA:
4.1		 1s8fA-3slgA:
18.87
1s8fB-3slgA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		4 / 8 LEU A 174
TYR A 141
THR A 120
TYR A 124
 None
 1.35A 1uw6P-3slgA:
undetectable
1uw6T-3slgA:
undetectable		 1uw6P-3slgA:
20.33
1uw6T-3slgA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		5 / 6 LEU A 170
ASN A 171
LEU A  75
LEU A 174
ILE A 238
 None
 1.31A 1z95A-3slgA:
undetectable		 1z95A-3slgA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 ILE A 206
ALA A 343
LEU A 185
ILE A 332
LEU A 264
 None
 0.92A 2cd2A-3slgA:
undetectable		 2cd2A-3slgA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		4 / 5 ILE A 237
HIS A 114
TYR A 250
GLY A 247
 None
 1.28A 3b9mA-3slgA:
undetectable		 3b9mA-3slgA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 THR A 313
VAL A 116
SER A 241
VAL A  73
THR A  27
 None
 1.22A 3frqA-3slgA:
undetectable		 3frqA-3slgA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 ALA A 272
LEU A 203
ILE A 181
SER A 196
LEU A 185
 None
 1.15A 3k2hB-3slgA:
undetectable		 3k2hB-3slgA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		3 / 3 LEU A 317
TRP A 319
GLY A 230
 None
 0.79A 3l35A-3slgA:
undetectable
3l35H-3slgA:
undetectable		 3l35A-3slgA:
7.34
3l35H-3slgA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		3 / 3 LEU A 317
TRP A 319
GLY A 230
 None
 0.73A 3l35B-3slgA:
undetectable
3l35K-3slgA:
undetectable		 3l35B-3slgA:
7.34
3l35K-3slgA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 GLY A  10
ILE A  15
ASP A  35
ASP A  56
PRO A 191
 None
 1.09A 3q87B-3slgA:
5.2		 3q87B-3slgA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		4 / 5 PHE A 224
THR A 200
PHE A 202
ILE A 181
 None
 1.14A 4jx1E-3slgA:
undetectable		 4jx1E-3slgA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 GLY A 182
GLY A 184
ALA A 335
ALA A 328
ASP A 228
 None
 0.96A 4kicA-3slgA:
5.2		 4kicA-3slgA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 GLY A 182
GLY A 184
ALA A 335
ALA A 328
ASP A 228
 None
 0.96A 4kicB-3slgA:
5.2		 4kicB-3slgA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		4 / 6 THR A  82
ALA A  84
THR A  85
VAL A  87
 None
None
None
CL  A 352 ( 4.6A)
 0.99A 5ecoA-3slgA:
undetectable		 5ecoA-3slgA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_A_SALA603_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		5 / 11 GLY A 217
ARG A 262
VAL A 261
PHE A 202
GLY A 218
 None
 1.24A 5yjsA-3slgA:
undetectable		 5yjsA-3slgA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_A_SALA603_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)		 3slg PBGP3 PROTEIN
(Burkholderia
pseudomallei) 		5 / 11 GLY A 217
ASN A 266
ARG A 262
PHE A 202
GLY A 218
 None
 1.46A 5yjsA-3slgA:
undetectable		 5yjsA-3slgA:
11.83