SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3slk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CBR_A_REAA200_1 (CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	ALA A 300 ALA A 303 PRO A 306 VAL A 474 ARG A 301	None	1.12A	1cbrA-3slkA: undetectable	1cbrA-3slkA: 10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CBR_B_REAB200_1 (CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	ALA A 300 ALA A 303 PRO A 306 VAL A 474 ARG A 301	None	1.12A	1cbrB-3slkA: undetectable	1cbrB-3slkA: 10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQU_A_EQIA329_0 (PROTEIN (ESTRADIOL 17 BETA-DEHYDROGENASE 1))	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 10	SER A 643 VAL A 644 LEU A 648 GLY A 683 PRO A 684	NDP A 802 (-3.2A) None None NDP A 802 (-4.6A) None	1.07A	1equA-3slkA: 8.0	1equA-3slkA: 20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBM_B_RTLB951_2 (PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN))	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 4	THR A 75 LEU A 79 VAL A 82 LEU A 86	None	0.54A	1fbmD-3slkA: undetectable	1fbmD-3slkA: 4.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FDS_A_ESTA350_1 (17-BETA-HYDROXYSTERO ID-DEHYDROGENASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	SER A 643 VAL A 644 TYR A 656 GLY A 683 PRO A 684	NDP A 802 (-3.2A) None None NDP A 802 (-4.6A) None	0.70A	1fdsA-3slkA: 19.9	1fdsA-3slkA: 20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FDU_A_ESTA351_1 (17-BETA-HYDROXYSTERO ID DEHYDROGENASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	SER A 643 VAL A 644 TYR A 656 GLY A 683 PRO A 684	NDP A 802 (-3.2A) None None NDP A 802 (-4.6A) None	0.87A	1fduA-3slkA: 17.7	1fduA-3slkA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FDU_C_ESTC353_1 (17-BETA-HYDROXYSTERO ID DEHYDROGENASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	SER A 643 VAL A 644 TYR A 656 GLY A 683 PRO A 684	NDP A 802 (-3.2A) None None NDP A 802 (-4.6A) None	0.85A	1fduC-3slkA: 8.1	1fduC-3slkA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_L_TRPL81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 7	GLY A 64 ALA A 118 THR A 75 THR A 74	None	0.86A	1gtfL-3slkA: undetectable 1gtfM-3slkA: undetectable	1gtfL-3slkA: 6.42 1gtfM-3slkA: 6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_N_TRPN81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 8	GLY A 64 ALA A 118 THR A 75 THR A 74	None	0.86A	1gtfN-3slkA: undetectable 1gtfO-3slkA: undetectable	1gtfN-3slkA: 6.42 1gtfO-3slkA: 6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_P_TRPP81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 8	GLY A 64 ALA A 118 THR A 75 THR A 74	None	0.83A	1gtnP-3slkA: undetectable 1gtnQ-3slkA: undetectable	1gtnP-3slkA: 6.42 1gtnQ-3slkA: 6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GWR_A_ESTA600_1 (OESTROGEN RECEPTOR)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 10	LEU A 238 LEU A 235 ALA A 234 LEU A 489 LEU A 203	None	1.33A	1gwrA-3slkA: undetectable	1gwrA-3slkA: 14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWI_C_115C4_1 (HMG-COA REDUCTASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 7	ARG A 95 VAL A 56 ASN A 92 ASP A 133	None	1.09A	1hwiC-3slkA: undetectable	1hwiC-3slkA: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWI_D_115D3_2 (HMG-COA REDUCTASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 7	ARG A 95 VAL A 56 ASN A 92 ASP A 133	None	1.09A	1hwiD-3slkA: undetectable	1hwiD-3slkA: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXD_A_ACRA733_1 (ALPHA AMYLASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 6	SER A 645 ASN A 660 LEU A 663 ASP A 664	None NDP A 802 ( 4.3A) None None	0.94A	1mxdA-3slkA: 2.4	1mxdA-3slkA: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXG_A_ACRA443_1 (ALPHA AMYLASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 8	SER A 645 ASN A 660 LEU A 663 ASP A 664	None NDP A 802 ( 4.3A) None None	0.96A	1mxgA-3slkA: 2.3	1mxgA-3slkA: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N4H_A_REAA500_1 (NUCLEAR RECEPTOR ROR-BETA)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 11	ILE A 342 ALA A 340 VAL A 495 LEU A 371 ALA A 356	None None None None NDP A 801 (-3.1A)	1.12A	1n4hA-3slkA: undetectable	1n4hA-3slkA: 14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OPJ_B_STIB4_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 6	LEU A 675 VAL A 290 ILE A 293 ARG A 221	None	1.11A	1opjB-3slkA: undetectable	1opjB-3slkA: 15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RV7_B_AB1B1001_1 (PROTEASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 11	ALA A 312 VAL A 308 LEU A 328 ALA A 350 VAL A 352	None	1.11A	1rv7A-3slkA: undetectable 1rv7B-3slkA: undetectable	1rv7A-3slkA: 8.78 1rv7B-3slkA: 8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SBR_B_VIBB504_1 (YKOF)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 6	PHE A 279 LEU A 247 ILE A 236 SER A 249	None	1.21A	1sbrA-3slkA: 1.2 1sbrB-3slkA: 1.3	1sbrA-3slkA: 13.39 1sbrB-3slkA: 13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UUJ_B_ACTB1077_0 (PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB ALPHA SUBUNIT)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	3 / 3	ARG A 232 TYR A 241 LYS A 422	None None NDP A 801 ( 4.1A)	1.03A	1uujB-3slkA: undetectable	1uujB-3slkA: 8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_A_CTXA11_1 (CES1 PROTEIN)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 8	TRP A 682 GLY A 599 LYS A 621 LEU A 663	None NDP A 802 (-3.7A) NDP A 802 (-2.5A) None	0.91A	1ya4A-3slkA: 2.5	1ya4A-3slkA: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_A_CTXA1_1 (CES1 PROTEIN)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	6 / 12	ALA A 569 GLY A 516 GLY A 517 LEU A 567 SER A 566 LEU A 554	None NDP A 802 (-3.3A) None None None None	1.45A	1ya4A-3slkA: 2.6	1ya4A-3slkA: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_B_CTXB1283_1 (CES1 PROTEIN)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 7	TRP A 682 GLY A 599 LYS A 621 LEU A 663	None NDP A 802 (-3.7A) NDP A 802 (-2.5A) None	0.92A	1ya4B-3slkA: 2.1	1ya4B-3slkA: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DQY_A_CHDA1_0 (LIVER CARBOXYLESTERASE 1)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 5	TRP A 682 GLY A 599 LYS A 621 LEU A 663	None NDP A 802 (-3.7A) NDP A 802 (-2.5A) None	0.99A	2dqyA-3slkA: 3.1	2dqyA-3slkA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_B_SAMB302_0 (YCGJ)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	GLY A 519 HIS A 688 ALA A 597 THR A 515 ALA A 523	NDP A 802 (-3.0A) None None None None	0.93A	2gluB-3slkA: 7.0	2gluB-3slkA: 16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_ACTA502_0 (CHORISMATE SYNTHASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	3 / 3	GLY A 202 ASP A 201 SER A 199	None	0.68A	2qhfA-3slkA: undetectable	2qhfA-3slkA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2R2V_C_ACTC36_0 (GCN4 LEUCINE ZIPPER)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 10	SER A 298 ALA A 300 ALA A 252 ALA A 303 SER A 304	None	1.41A	2r2vC-3slkA: undetectable 2r2vF-3slkA: undetectable 2r2vG-3slkA: undetectable	2r2vC-3slkA: 3.66 2r2vF-3slkA: 3.66 2r2vG-3slkA: 3.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RK8_A_PPFA3969_1 (PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP])	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 8	LYS A 422 ASP A 444 ARG A 232 ALA A 245	NDP A 801 ( 4.1A) NDP A 801 (-3.6A) None None	1.34A	2rk8A-3slkA: undetectable	2rk8A-3slkA: 20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_K_ASDK1224_1 (GLUTATHIONE S-TRANSFERASE A3)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 6	PHE A 464 LEU A 310 ALA A 340 LEU A 344	None	0.96A	2vcvK-3slkA: 2.5	2vcvK-3slkA: 14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W3B_B_FOLB401_1 (DIHYDROFOLATE REDUCTASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	3 / 3	GLU A 484 GLN A 671 ARG A 678	None	0.99A	2w3bB-3slkA: 2.1	2w3bB-3slkA: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B9L_A_AZZA1009_1 (SERUM ALBUMIN)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 8	GLU A 402 VAL A 431 HIS A 435 ARG A 426	None	1.17A	3b9lA-3slkA: undetectable	3b9lA-3slkA: 22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	3 / 3	SER A 645 GLY A 651 GLY A 654	None	0.45A	3bogA-3slkA: undetectable 3bogC-3slkA: undetectable	3bogA-3slkA: undetectable 3bogC-3slkA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 4	SER A 645 GLY A 646 GLY A 651 GLY A 654	None	0.61A	3bogB-3slkA: undetectable 3bogD-3slkA: undetectable	3bogB-3slkA: undetectable 3bogD-3slkA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3007_1 (TRANSCRIPTIONAL REGULATOR TCAR)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 9	THR A 44 ALA A 45 LEU A 47 ALA A 49 ARG A 90	None	1.27A	3kp6B-3slkA: undetectable	3kp6B-3slkA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MBG_C_ACTC800_0 (FAD-LINKED SULFHYDRYL OXIDASE ALR)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	3 / 3	ASP A 70 ARG A 67 ALA A 69	None	0.79A	3mbgC-3slkA: undetectable	3mbgC-3slkA: 10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NY4_A_SMXA310_1 (BETA-LACTAMASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 8	ARG A 191 ALA A 278 TRP A 190 GLY A 187 PRO A 185	None	0.93A	3ny4A-3slkA: undetectable	3ny4A-3slkA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UA1_A_08YA600_1 (CYTOCHROME P450 3A4)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	ILE A 307 PHE A 279 THR A 501 ALA A 245 ALA A 237	None	1.35A	3ua1A-3slkA: undetectable	3ua1A-3slkA: 21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UCB_B_017B202_1 (PROTEASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 7	PRO A 276 ARG A 191 GLY A 280 PRO A 281	None	1.14A	3ucbB-3slkA: undetectable	3ucbB-3slkA: 8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7X_B_SASB804_1 (SEPIAPTERIN REDUCTASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	SER A 679 LEU A 640 ALA A 118 GLY A 66 LEU A 115	None	1.12A	4j7xB-3slkA: 17.2	4j7xB-3slkA: 18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MGH_A_ACTA1320_0 (PHOSPHORIBOSYLFORMYL GLYCINAMIDINE SYNTHASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 5	VAL A 56 LEU A 154 LEU A 96 ARG A 95	None	0.88A	4mghA-3slkA: 3.1	4mghA-3slkA: 22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_C_IPHC101_0 (INSULIN)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 11	LEU A 13 ALA A 149 LEU A 163 VAL A 136 LEU A 97	None	1.07A	4p65C-3slkA: undetectable 4p65D-3slkA: undetectable 4p65J-3slkA: undetectable 4p65L-3slkA: undetectable	4p65C-3slkA: 2.26 4p65D-3slkA: 3.66 4p65J-3slkA: 3.66 4p65L-3slkA: 3.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVV_H_BO2H301_1 (PROTEASOME SUBUNIT BETA TYPE-2)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 11	THR A 113 GLN A 669 GLY A 64 ALA A 116 THR A 74	None	1.16A	4qvvH-3slkA: undetectable	4qvvH-3slkA: 13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVV_V_BO2V301_1 (PROTEASOME SUBUNIT BETA TYPE-2)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 11	THR A 113 GLN A 669 GLY A 64 ALA A 116 THR A 74	None	1.16A	4qvvV-3slkA: undetectable	4qvvV-3slkA: 13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVY_H_BO2H301_1 (PROTEASOME SUBUNIT BETA TYPE-2)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 11	THR A 113 GLN A 669 GLY A 64 ALA A 116 THR A 74	None	1.15A	4qvyH-3slkA: undetectable	4qvyH-3slkA: 13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RN6_B_15UB301_1 (THROMBIN HEAVY CHAIN)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	LEU A 529 TRP A 682 ALA A 598 GLY A 522 GLY A 516	None None NDP A 802 (-3.8A) None NDP A 802 (-3.3A)	0.93A	4rn6B-3slkA: undetectable	4rn6B-3slkA: 15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUM_B_IMNB501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 11	GLY A 251 ILE A 453 MET A 456 LEU A 457 LEU A 460	None	0.95A	4xumB-3slkA: undetectable	4xumB-3slkA: 16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z91_J_4LEJ401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	6 / 9	LEU A 500 ALA A 482 LEU A 192 LEU A 247 ALA A 237 ALA A 485	None	1.23A	4z91F-3slkA: undetectable 4z91G-3slkA: undetectable 4z91H-3slkA: undetectable 4z91I-3slkA: undetectable 4z91J-3slkA: undetectable	4z91F-3slkA: 17.41 4z91G-3slkA: 17.41 4z91H-3slkA: 17.41 4z91I-3slkA: 17.41 4z91J-3slkA: 17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CDP_H_EVPH2101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 6	SER A 692 GLU A 696 GLY A 516 GLY A 522	None None NDP A 802 (-3.3A) None	0.93A	5cdpA-3slkA: undetectable 5cdpB-3slkA: 3.2	5cdpA-3slkA: 21.18 5cdpB-3slkA: 13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEZ_L_TRPL101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 8	GLY A 64 ALA A 118 THR A 75 THR A 74	None	0.85A	5eezL-3slkA: undetectable 5eezV-3slkA: undetectable	5eezL-3slkA: 6.42 5eezV-3slkA: 6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF1_L_TRPL101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 8	GLY A 64 ALA A 118 THR A 75 THR A 74	None	0.85A	5ef1L-3slkA: undetectable 5ef1V-3slkA: undetectable	5ef1L-3slkA: 6.42 5ef1V-3slkA: 6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF2_L_TRPL101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 8	GLY A 64 ALA A 118 THR A 75 THR A 74	None	0.85A	5ef2L-3slkA: undetectable 5ef2V-3slkA: undetectable	5ef2L-3slkA: 6.42 5ef2V-3slkA: 6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G44_A_YTZA1512_1 (NUCLEAR RECEPTOR ROR-GAMMA)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 9	LEU A 663 LEU A 640 ALA A 118 VAL A 112 ALA A 667	None	1.46A	5g44A-3slkA: undetectable	5g44A-3slkA: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GS4_A_ESTA603_2 (ESTROGEN RECEPTOR)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 6	LEU A 235 LEU A 200 LEU A 486 PHE A 231	None None None NDP A 801 (-4.4A)	0.65A	5gs4A-3slkA: undetectable	5gs4A-3slkA: 14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HWA_A_GCSA303_1 (CHITOSANASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	4 / 5	HIS A 331 VAL A 364 GLY A 335 ALA A 334	None None NDP A 801 (-3.3A) None	1.06A	5hwaA-3slkA: undetectable	5hwaA-3slkA: 14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_B_CELB602_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	LEU A 663 ALA A 658 VAL A 622 GLY A 624 LEU A 629	None	0.92A	5jw1B-3slkA: undetectable	5jw1B-3slkA: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KIR_A_RCXA601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	LEU A 663 ALA A 658 VAL A 622 GLY A 624 LEU A 629	None	0.87A	5kirA-3slkA: undetectable	5kirA-3slkA: 21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V5Z_A_1YNA602_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	3 / 3	GLY A 218 THR A 445 PRO A 450	None NDP A 801 (-3.4A) None	0.58A	5v5zA-3slkA: undetectable	5v5zA-3slkA: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCG_A_08YA602_1 (CYTOCHROME P450 3A4)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	ILE A 307 PHE A 279 THR A 501 ALA A 245 ALA A 237	None	1.26A	5vcgA-3slkA: undetectable	5vcgA-3slkA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VM8_B_SAMB301_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 10	VAL A 495 GLY A 496 GLY A 336 ILE A 342 ALA A 363	None None NDP A 801 (-3.7A) None None	0.91A	5vm8B-3slkA: 2.5	5vm8B-3slkA: 16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIP_A_HFGA1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	LEU A 538 VAL A 530 ARG A 527 THR A 693 GLY A 689	None	1.27A	5xipA-3slkA: undetectable	5xipA-3slkA: 19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIQ_D_HFGD1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	3slk	POLYKETIDE SYNTHASE EXTENDER MODULE 2 (Saccharopolyspor a spinosa)	5 / 12	LEU A 538 VAL A 530 ARG A 527 THR A 693 GLY A 689	None	1.34A	5xiqD-3slkA: undetectable	5xiqD-3slkA: 20.15

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CBR_A_REAA200_1","CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"ALA A 300;ALA A 303;PRO A 306;VAL A 474;ARG A 301","None","1.12A","1cbrA-3slkA:undetectable","1cbrA-3slkA:10.91"],["1CBR_B_REAB200_1","CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"ALA A 300;ALA A 303;PRO A 306;VAL A 474;ARG A 301","None","1.12A","1cbrB-3slkA:undetectable","1cbrB-3slkA:10.91"],["1EQU_A_EQIA329_0","PROTEIN (ESTRADIOL 17 BETA-DEHYDROGENASE 1)","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"SER A 643;VAL A 644;LEU A 648;GLY A 683;PRO A 684","NDP A 802 (-3.2A);None;None;NDP A 802 (-4.6A);None","1.07A","1equA-3slkA:8.0","1equA-3slkA:20.65"],["1FBM_B_RTLB951_2","PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN)","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"THR A  75;LEU A  79;VAL A  82;LEU A  86","None","0.54A","1fbmD-3slkA:undetectable","1fbmD-3slkA:4.43"],["1FDS_A_ESTA350_1","17-BETA-HYDROXYSTEROID-DEHYDROGENASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"SER A 643;VAL A 644;TYR A 656;GLY A 683;PRO A 684","NDP A 802 (-3.2A);None;None;NDP A 802 (-4.6A);None","0.70A","1fdsA-3slkA:19.9","1fdsA-3slkA:20.65"],["1FDU_A_ESTA351_1","17-BETA-HYDROXYSTEROID DEHYDROGENASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"SER A 643;VAL A 644;TYR A 656;GLY A 683;PRO A 684","NDP A 802 (-3.2A);None;None;NDP A 802 (-4.6A);None","0.87A","1fduA-3slkA:17.7","1fduA-3slkA:20.78"],["1FDU_C_ESTC353_1","17-BETA-HYDROXYSTEROID DEHYDROGENASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"SER A 643;VAL A 644;TYR A 656;GLY A 683;PRO A 684","NDP A 802 (-3.2A);None;None;NDP A 802 (-4.6A);None","0.85A","1fduC-3slkA:8.1","1fduC-3slkA:20.78"],["1GTF_L_TRPL81_0","TRP RNA-BINDING ATTENUATION PROTEIN (TRAP)","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"GLY A  64;ALA A 118;THR A  75;THR A  74","None","0.86A","1gtfL-3slkA:undetectable;1gtfM-3slkA:undetectable","1gtfL-3slkA:6.42;1gtfM-3slkA:6.42"],["1GTF_N_TRPN81_0","TRP RNA-BINDING ATTENUATION PROTEIN (TRAP)","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"GLY A  64;ALA A 118;THR A  75;THR A  74","None","0.86A","1gtfN-3slkA:undetectable;1gtfO-3slkA:undetectable","1gtfN-3slkA:6.42;1gtfO-3slkA:6.42"],["1GTN_P_TRPP81_0","TRP RNA-BINDING ATTENUATION PROTEIN","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"GLY A  64;ALA A 118;THR A  75;THR A  74","None","0.83A","1gtnP-3slkA:undetectable;1gtnQ-3slkA:undetectable","1gtnP-3slkA:6.42;1gtnQ-3slkA:6.42"],["1GWR_A_ESTA600_1","OESTROGEN RECEPTOR","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"LEU A 238;LEU A 235;ALA A 234;LEU A 489;LEU A 203","None","1.33A","1gwrA-3slkA:undetectable","1gwrA-3slkA:14.76"],["1HWI_C_115C4_1","HMG-COA REDUCTASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"ARG A  95;VAL A  56;ASN A  92;ASP A 133","None","1.09A","1hwiC-3slkA:undetectable","1hwiC-3slkA:22.92"],["1HWI_D_115D3_2","HMG-COA REDUCTASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"ARG A  95;VAL A  56;ASN A  92;ASP A 133","None","1.09A","1hwiD-3slkA:undetectable","1hwiD-3slkA:22.92"],["1MXD_A_ACRA733_1","ALPHA AMYLASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"SER A 645;ASN A 660;LEU A 663;ASP A 664","None;NDP A 802 ( 4.3A);None;None","0.94A","1mxdA-3slkA:2.4","1mxdA-3slkA:18.66"],["1MXG_A_ACRA443_1","ALPHA AMYLASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"SER A 645;ASN A 660;LEU A 663;ASP A 664","None;NDP A 802 ( 4.3A);None;None","0.96A","1mxgA-3slkA:2.3","1mxgA-3slkA:18.66"],["1N4H_A_REAA500_1","NUCLEAR RECEPTOR ROR-BETA","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"ILE A 342;ALA A 340;VAL A 495;LEU A 371;ALA A 356","None;None;None;None;NDP A 801 (-3.1A)","1.12A","1n4hA-3slkA:undetectable","1n4hA-3slkA:14.23"],["1OPJ_B_STIB4_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"LEU A 675;VAL A 290;ILE A 293;ARG A 221","None","1.11A","1opjB-3slkA:undetectable","1opjB-3slkA:15.06"],["1RV7_B_AB1B1001_1","PROTEASE;PROTEASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"ALA A 312;VAL A 308;LEU A 328;ALA A 350;VAL A 352","None","1.11A","1rv7A-3slkA:undetectable;1rv7B-3slkA:undetectable","1rv7A-3slkA:8.78;1rv7B-3slkA:8.78"],["1SBR_B_VIBB504_1","YKOF;YKOF","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"PHE A 279;LEU A 247;ILE A 236;SER A 249","None","1.21A","1sbrA-3slkA:1.2;1sbrB-3slkA:1.3","1sbrA-3slkA:13.39;1sbrB-3slkA:13.39"],["1UUJ_B_ACTB1077_0","PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB ALPHA SUBUNIT","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",3,"ARG A 232;TYR A 241;LYS A 422","None;None;NDP A 801 ( 4.1A)","1.03A","1uujB-3slkA:undetectable","1uujB-3slkA:8.28"],["1YA4_A_CTXA11_1","CES1 PROTEIN","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"TRP A 682;GLY A 599;LYS A 621;LEU A 663","None;NDP A 802 (-3.7A);NDP A 802 (-2.5A);None","0.91A","1ya4A-3slkA:2.5","1ya4A-3slkA:22.63"],["1YA4_A_CTXA1_1","CES1 PROTEIN","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",6,"ALA A 569;GLY A 516;GLY A 517;LEU A 567;SER A 566;LEU A 554","None;NDP A 802 (-3.3A);None;None;None;None","1.45A","1ya4A-3slkA:2.6","1ya4A-3slkA:22.63"],["1YA4_B_CTXB1283_1","CES1 PROTEIN","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"TRP A 682;GLY A 599;LYS A 621;LEU A 663","None;NDP A 802 (-3.7A);NDP A 802 (-2.5A);None","0.92A","1ya4B-3slkA:2.1","1ya4B-3slkA:22.63"],["2DQY_A_CHDA1_0","LIVER CARBOXYLESTERASE 1","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"TRP A 682;GLY A 599;LYS A 621;LEU A 663","None;NDP A 802 (-3.7A);NDP A 802 (-2.5A);None","0.99A","2dqyA-3slkA:3.1","2dqyA-3slkA:22.70"],["2GLU_B_SAMB302_0","YCGJ","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"GLY A 519;HIS A 688;ALA A 597;THR A 515;ALA A 523","NDP A 802 (-3.0A);None;None;None;None","0.93A","2gluB-3slkA:7.0","2gluB-3slkA:16.08"],["2QHF_A_ACTA502_0","CHORISMATE SYNTHASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",3,"GLY A 202;ASP A 201;SER A 199","None","0.68A","2qhfA-3slkA:undetectable","2qhfA-3slkA:23.44"],["2R2V_C_ACTC36_0","GCN4 LEUCINE ZIPPER","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"SER A 298;ALA A 300;ALA A 252;ALA A 303;SER A 304","None","1.41A","2r2vC-3slkA:undetectable;2r2vF-3slkA:undetectable;2r2vG-3slkA:undetectable","2r2vC-3slkA:3.66;2r2vF-3slkA:3.66;2r2vG-3slkA:3.66"],["2RK8_A_PPFA3969_1","PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP]","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"LYS A 422;ASP A 444;ARG A 232;ALA A 245","NDP A 801 ( 4.1A);NDP A 801 (-3.6A);None;None","1.34A","2rk8A-3slkA:undetectable","2rk8A-3slkA:20.86"],["2VCV_K_ASDK1224_1","GLUTATHIONE S-TRANSFERASE A3","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"PHE A 464;LEU A 310;ALA A 340;LEU A 344","None","0.96A","2vcvK-3slkA:2.5","2vcvK-3slkA:14.05"],["2W3B_B_FOLB401_1","DIHYDROFOLATE REDUCTASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",3,"GLU A 484;GLN A 671;ARG A 678","None","0.99A","2w3bB-3slkA:2.1","2w3bB-3slkA:10.80"],["3B9L_A_AZZA1009_1","SERUM ALBUMIN","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"GLU A 402;VAL A 431;HIS A 435;ARG A 426","None","1.17A","3b9lA-3slkA:undetectable","3b9lA-3slkA:22.37"],["3BOG_C_DHIC8_0","6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",3,"SER A 645;GLY A 651;GLY A 654","None","0.45A","3bogA-3slkA:undetectable;3bogC-3slkA:undetectable","3bogA-3slkA:undetectable;3bogC-3slkA:undetectable"],["3BOG_D_DHID8_0","6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"SER A 645;GLY A 646;GLY A 651;GLY A 654","None","0.61A","3bogB-3slkA:undetectable;3bogD-3slkA:undetectable","3bogB-3slkA:undetectable;3bogD-3slkA:undetectable"],["3KP6_B_SALB3007_1","TRANSCRIPTIONAL REGULATOR TCAR","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"THR A  44;ALA A  45;LEU A  47;ALA A  49;ARG A  90","None","1.27A","3kp6B-3slkA:undetectable","3kp6B-3slkA:10.31"],["3MBG_C_ACTC800_0","FAD-LINKED SULFHYDRYL OXIDASE ALR","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",3,"ASP A  70;ARG A  67;ALA A  69","None","0.79A","3mbgC-3slkA:undetectable","3mbgC-3slkA:10.69"],["3NY4_A_SMXA310_1","BETA-LACTAMASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"ARG A 191;ALA A 278;TRP A 190;GLY A 187;PRO A 185","None","0.93A","3ny4A-3slkA:undetectable","3ny4A-3slkA:19.05"],["3UA1_A_08YA600_1","CYTOCHROME P450 3A4","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"ILE A 307;PHE A 279;THR A 501;ALA A 245;ALA A 237","None","1.35A","3ua1A-3slkA:undetectable","3ua1A-3slkA:21.46"],["3UCB_B_017B202_1","PROTEASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"PRO A 276;ARG A 191;GLY A 280;PRO A 281","None","1.14A","3ucbB-3slkA:undetectable","3ucbB-3slkA:8.64"],["4J7X_B_SASB804_1","SEPIAPTERIN REDUCTASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"SER A 679;LEU A 640;ALA A 118;GLY A  66;LEU A 115","None","1.12A","4j7xB-3slkA:17.2","4j7xB-3slkA:18.62"],["4MGH_A_ACTA1320_0","PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"VAL A  56;LEU A 154;LEU A  96;ARG A  95","None","0.88A","4mghA-3slkA:3.1","4mghA-3slkA:22.84"],["4P65_C_IPHC101_0","INSULIN","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"LEU A  13;ALA A 149;LEU A 163;VAL A 136;LEU A  97","None","1.07A","4p65C-3slkA:undetectable;4p65D-3slkA:undetectable;4p65J-3slkA:undetectable;4p65L-3slkA:undetectable","4p65C-3slkA:2.26;4p65D-3slkA:3.66;4p65J-3slkA:3.66;4p65L-3slkA:3.66"],["4QVV_H_BO2H301_1","PROTEASOME SUBUNIT BETA TYPE-2","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"THR A 113;GLN A 669;GLY A  64;ALA A 116;THR A  74","None","1.16A","4qvvH-3slkA:undetectable","4qvvH-3slkA:13.76"],["4QVV_V_BO2V301_1","PROTEASOME SUBUNIT BETA TYPE-2","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"THR A 113;GLN A 669;GLY A  64;ALA A 116;THR A  74","None","1.16A","4qvvV-3slkA:undetectable","4qvvV-3slkA:13.76"],["4QVY_H_BO2H301_1","PROTEASOME SUBUNIT BETA TYPE-2","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"THR A 113;GLN A 669;GLY A  64;ALA A 116;THR A  74","None","1.15A","4qvyH-3slkA:undetectable","4qvyH-3slkA:13.76"],["4RN6_B_15UB301_1","THROMBIN HEAVY CHAIN","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"LEU A 529;TRP A 682;ALA A 598;GLY A 522;GLY A 516","None;None;NDP A 802 (-3.8A);None;NDP A 802 (-3.3A)","0.93A","4rn6B-3slkA:undetectable","4rn6B-3slkA:15.82"],["4XUM_B_IMNB501_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"GLY A 251;ILE A 453;MET A 456;LEU A 457;LEU A 460","None","0.95A","4xumB-3slkA:undetectable","4xumB-3slkA:16.17"],["4Z91_J_4LEJ401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1;GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1;GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1;GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1;GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",6,"LEU A 500;ALA A 482;LEU A 192;LEU A 247;ALA A 237;ALA A 485","None","1.23A","4z91F-3slkA:undetectable;4z91G-3slkA:undetectable;4z91H-3slkA:undetectable;4z91I-3slkA:undetectable;4z91J-3slkA:undetectable","4z91F-3slkA:17.41;4z91G-3slkA:17.41;4z91H-3slkA:17.41;4z91I-3slkA:17.41;4z91J-3slkA:17.41"],["5CDP_H_EVPH2101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"SER A 692;GLU A 696;GLY A 516;GLY A 522","None;None;NDP A 802 (-3.3A);None","0.93A","5cdpA-3slkA:undetectable;5cdpB-3slkA:3.2","5cdpA-3slkA:21.18;5cdpB-3slkA:13.04"],["5EEZ_L_TRPL101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"GLY A  64;ALA A 118;THR A  75;THR A  74","None","0.85A","5eezL-3slkA:undetectable;5eezV-3slkA:undetectable","5eezL-3slkA:6.42;5eezV-3slkA:6.42"],["5EF1_L_TRPL101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"GLY A  64;ALA A 118;THR A  75;THR A  74","None","0.85A","5ef1L-3slkA:undetectable;5ef1V-3slkA:undetectable","5ef1L-3slkA:6.42;5ef1V-3slkA:6.42"],["5EF2_L_TRPL101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"GLY A  64;ALA A 118;THR A  75;THR A  74","None","0.85A","5ef2L-3slkA:undetectable;5ef2V-3slkA:undetectable","5ef2L-3slkA:6.42;5ef2V-3slkA:6.42"],["5G44_A_YTZA1512_1","NUCLEAR RECEPTOR ROR-GAMMA","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"LEU A 663;LEU A 640;ALA A 118;VAL A 112;ALA A 667","None","1.46A","5g44A-3slkA:undetectable","5g44A-3slkA:18.36"],["5GS4_A_ESTA603_2","ESTROGEN RECEPTOR","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"LEU A 235;LEU A 200;LEU A 486;PHE A 231","None;None;None;NDP A 801 (-4.4A)","0.65A","5gs4A-3slkA:undetectable","5gs4A-3slkA:14.51"],["5HWA_A_GCSA303_1","CHITOSANASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",4,"HIS A 331;VAL A 364;GLY A 335;ALA A 334","None;None;NDP A 801 (-3.3A);None","1.06A","5hwaA-3slkA:undetectable","5hwaA-3slkA:14.71"],["5JW1_B_CELB602_1","PROSTAGLANDIN G\/H SYNTHASE 2","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"LEU A 663;ALA A 658;VAL A 622;GLY A 624;LEU A 629","None","0.92A","5jw1B-3slkA:undetectable","5jw1B-3slkA:21.60"],["5KIR_A_RCXA601_1","PROSTAGLANDIN G\/H SYNTHASE 2","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"LEU A 663;ALA A 658;VAL A 622;GLY A 624;LEU A 629","None","0.87A","5kirA-3slkA:undetectable","5kirA-3slkA:21.23"],["5V5Z_A_1YNA602_2","LANOSTEROL 14-ALPHA DEMETHYLASE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",3,"GLY A 218;THR A 445;PRO A 450","None;NDP A 801 (-3.4A);None","0.58A","5v5zA-3slkA:undetectable","5v5zA-3slkA:20.68"],["5VCG_A_08YA602_1","CYTOCHROME P450 3A4","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"ILE A 307;PHE A 279;THR A 501;ALA A 245;ALA A 237","None","1.26A","5vcgA-3slkA:undetectable","5vcgA-3slkA:21.53"],["5VM8_B_SAMB301_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"VAL A 495;GLY A 496;GLY A 336;ILE A 342;ALA A 363","None;None;NDP A 801 (-3.7A);None;None","0.91A","5vm8B-3slkA:2.5","5vm8B-3slkA:16.58"],["5XIP_A_HFGA1003_0","PROLYL-TRNA SYNTHETASE, PUTATIVE","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"LEU A 538;VAL A 530;ARG A 527;THR A 693;GLY A 689","None","1.27A","5xipA-3slkA:undetectable","5xipA-3slkA:19.60"],["5XIQ_D_HFGD1002_0","PROLYL-TRNA SYNTHETASE (PRORS)","3slk","POLYKETIDE SYNTHASE EXTENDER MODULE 2","Saccharopolyspora spinosa",5,"LEU A 538;VAL A 530;ARG A 527;THR A 693;GLY A 689","None","1.34A","5xiqD-3slkA:undetectable","5xiqD-3slkA:20.15"]]